Zobrazeno 1 - 10
of 270
pro vyhledávání: '"David F, Jarrard"'
Autor:
Tamara S. Rodems, Erika Heninger, Charlotte N. Stahlfeld, Cole S. Gilsdorf, Kristin N. Carlson, Madison R. Kircher, Anupama Singh, Timothy E. G. Krueger, David J. Beebe, David F. Jarrard, Douglas G. McNeel, Michael C. Haffner, Joshua M. Lang
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Loss of HLA-I gene expression in prostate cancer is associated with repressive chromatin states, which can be reversed by pharmacological DNMT and HDAC inhibition leading to increased activation of co-cultured tumor-specific CD8+ T-cells.
Externí odkaz:
https://doaj.org/article/1153e9cc0b6a481e85909d4a3f28af7d
Autor:
Jonathan H. Wang, Pablo Sierra, Kyle A. Richards, E. Jason Abel, Glen O. Allen, Tracy M. Downs, David F. Jarrard
Publikováno v:
BMC Urology, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background To assess factors that can predict active surveillance (AS) failure on serial transrectal ultrasound guided biopsies in patients with low-risk prostate cancer. Methods We evaluated the records of 144 consecutive patients enrolled
Externí odkaz:
https://doaj.org/article/85707b218bca44779c2ac3ed99b25dbb
Autor:
Tyler Etheridge, Shivashankar Damodaran, Adam Schultz, Kyle A. Richards, Joseph Gawdzik, Bing Yang, Vincent Cryns, David F. Jarrard
Publikováno v:
Asian Journal of Urology, Vol 6, Iss 1, Pp 57-64 (2019)
Androgen deprivation therapy (ADT) has been the standard of care for the last 75 years in metastatic hormone sensitive prostate cancer (PCa). However, this approach is rarely curative. Recent clinical trials have demonstrated that ADT combined with o
Externí odkaz:
https://doaj.org/article/e0c83ab6063445e6bd152cd6075daf92
Autor:
William Lowrance, Robert Dreicer, David F. Jarrard, Kristen R. Scarpato, Sennett K. Kim, Erin Kirkby, David I. Buckley, Jessica C. Griffin, Michael S. Cookson
Publikováno v:
Journal of Urology. 209:1082-1090
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae4e3cc2053e092ad20e3406dc77fc0e
https://doi.org/10.1097/ju.0000000000003452
https://doi.org/10.1097/ju.0000000000003452
Autor:
Anthony J. Cesnik, Bing Yang, Andrew Truong, Tyler Etheridge, Michele Spiniello, Maisie I. Steinbrink, Michael R. Shortreed, Brian L. Frey, David F. Jarrard, Lloyd M. Smith
Publikováno v:
Translational Oncology, Vol 11, Iss 3, Pp 808-814 (2018)
INTRODUCTION: The molecular mechanisms underlying aggressive versus indolent disease are not fully understood. Recent research has implicated a class of molecules known as long noncoding RNAs (lncRNAs) in tumorigenesis and progression of cancer. Our
Externí odkaz:
https://doaj.org/article/946ec19bd6de47cfb548eee57a882295
Autor:
Brian P. Johnson, Ross A. Vitek, Peter G. Geiger, Wei Huang, David F. Jarrard, Joshua M. Lang, David J. Beebe
Publikováno v:
BioTechniques, Vol 64, Iss 1, Pp 13-19 (2018)
Cellular heterogeneity within the tissue microenvironment may underlie chemotherapeutic resistance and response, enabling tumor evolution; however, this heterogeneity it is difficult to characterize. Here, we present a new approach—pathology-guided
Externí odkaz:
https://doaj.org/article/381f3c1fdb2449d1af2a4c733b9224c9
Autor:
David F. Jarrard, Vincent L. Cryns, Kyle A. Richards, Dmitry Malin, Tyler Etheridge, Joseph Gawdzik, Adam Schultz, Mikolaj J. Filon, Tariq A. Khemees, Shivashankar Damodaran, Bing Yang
The initiation of androgen-deprivation therapy (ADT) induces susceptibilities in prostate cancer cells that make them vulnerable to synergistic treatment and enhanced cell death. Senescence results in cell-cycle arrest, but cells remain viable. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a68edb553efee842491ff4568a7673
https://doi.org/10.1158/1535-7163.c.6542298
https://doi.org/10.1158/1535-7163.c.6542298
Autor:
David F. Jarrard, Vincent L. Cryns, Kyle A. Richards, Dmitry Malin, Tyler Etheridge, Joseph Gawdzik, Adam Schultz, Mikolaj J. Filon, Tariq A. Khemees, Shivashankar Damodaran, Bing Yang
All supplementary table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273a894f38ad61b04579a09f61ce5d28
https://doi.org/10.1158/1535-7163.22519107
https://doi.org/10.1158/1535-7163.22519107
Autor:
Alicia K, Morgans, Yu-Hui, Chen, David F, Jarrard, Michael, Carducci, Glenn, Liu, Mario, Eisenberger, Elizabeth R, Plimack, Alan, Bryce, Jorge A, Garcia, Robert, Dreicer, Nicholas J, Vogelzang, Joel, Picus, Daniel, Shevrin, Maha, Hussain, Robert S, DiPaola, David, Cella, Christopher J, Sweeney
Publikováno v:
The Prostate. 82:1176-1185
E3805 (CHAARTED) is a phase 3 trial demonstrating improved survival for men with metastatic hormone-sensitive prostate cancer (mHSPC) randomized to treatment with docetaxel (D) and androgen-deprivation therapy (ADT) versus ADT alone. We assessed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6888e81ae01f259e2d26d59b01bed4b9
https://doi.org/10.1002/pros.24369
https://doi.org/10.1002/pros.24369
Autor:
Austin V. Carr, Brian L. Frey, Mark Scalf, Anthony J. Cesnik, Zach Rolfs, Kyndal A. Pike, Bing Yang, Mark P. Keller, David F. Jarrard, Michael R. Shortreed, Lloyd M. Smith
Publikováno v:
J Proteome Res
Interpreting proteomics data remains challenging due to the large number of proteins that are quantified by modern mass spectrometry methods. Weighted gene correlation network analysis (WGCNA) can identify groups of biologically related proteins usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5e64e8362d6e726bf3ef10f2422dd4
https://doi.org/10.1021/acs.jproteome.1c00756
https://doi.org/10.1021/acs.jproteome.1c00756