Zobrazeno 1 - 10
of 12
pro vyhledávání: '"David Eric Symer"'
Autor:
William H. Westra, Wayne M. Koch, Anna L. Trivett, David Eric Symer, Weihong Xiao, Maura L. Gillison, Yuri Agrawal
Publikováno v:
Clinical Cancer Research. 14:7143-7150
Purpose: Oral human papillomavirus (HPV) infection is a risk factor for head and neck squamous cell carcinoma (HNSCC), and is a concern for patients with HPV-positive HNSCC and their partners. The prevalence of oral HPV infection before and after can
Autor:
Giovanni Parmigiani, Emerita Caputo, Carla Connelly, Suzanne Szak, Gregory J. Cost, Jef D. Boeke, David Eric Symer
Publikováno v:
Cell. 110:327-338
Retrotransposons have shaped eukaryotic genomes for millions of years. To analyze the consequences of human L1 retrotransposition, we developed a genetic system to recover many new L1 insertions in somatic cells. Forty-two de novo integrants were rec
Evidence for a Causal Association Between Human Papillomavirus and a Subset of Head and Neck Cancers
Autor:
Michael Spafford, David Eric Symer, Michael P. Viglione, Maura L. Gillison, Marianna Zahurak, Wayne M. Koch, Richard W. Daniel, William H. Westra, Keerti V. Shah, Li Wu, David Sidransky, Randolph B. Capone
Publikováno v:
Journal of the National Cancer Institute. 92:709-720
Background: High-risk human papillomaviruses (HPVs) are etiologic agents for anogenital tract cancers and have been detected in head and neck squamous cell carcinomas (HNSCCs). We investigated, retrospectively, an etiologic role for HPVs in a large s
Publikováno v:
The Journal of Experimental Medicine
Platelets are potent antibody- and complement-dependent cytotoxic effector cells. We showed previously that a single platelet can lyse a target cell sensitized with immunoglobulin G (IgG) and complement components up to C3 (C integral of 3b denotes t
Autor:
Judith Bender, David Eric Symer
Publikováno v:
Nature. 411:147-149
'Jumping genes' can wreak havoc by hopping about a genome. Some plants can keep them under control by modifying them with certain chemical groups.
Publikováno v:
The Journal of Experimental Medicine
We present evidence that direct T cell receptor (TCR) occupancy by antigen can either activate or inhibit T cells, depending upon whether or not a threshold number of local TCRs are crosslinked by multivalent arrays of the antigen. Variants of Jurkat
Autor:
Renee Z. Dintzis, Hyun S. Shin, Robert F. Siliciano, Phyllis Hao, Ellis L. Reinherz, Don J. Diamond, Howard M. Dintzis, Peter Szalay, David Eric Symer
Publikováno v:
The Journal of Experimental Medicine
We have isolated T cell receptor (TCR) cDNAs from fluorescein (FL)-specific human T cell clones (alpha FL beta FL), and transferred them to TCR beta- Jurkat cells in order to study direct FL-binding to the TCR. Using either FL-conjugated polymers (FL
Publikováno v:
Proteins. 16(3)
The immunogenicity of a folded, all D-amino acid protein- rubredoxin, has been compared with that for the corresponding L-protein enantiomer. Following multiple administrations with alum adjuvant, the L-protein induced a strong, specific lgG antibody
Autor:
David Eric Symer
Publikováno v:
JNCI Journal of the National Cancer Institute. 89:966-967
Publikováno v:
The Journal of Cell Biology
Immunofluorescence analysis of mammalian lymphocytes using antiserum directed against chicken erythrocyte alpha-spectrin revealed a lymphocyte population in which spectrin antigen was arranged in the form of a discrete cap (hereafter referred to as c