Zobrazeno 1 - 7
of 7
pro vyhledávání: '"David Engers"'
Publikováno v:
Journal of Pharmaceutical Sciences. 99:3815-3825
The effect of water vapor sorption on the local structure of poly(vinylpyrrolidone) (PVP), was investigated using high-quality X-ray powder diffraction (XRPD). To examine the effects on molecular scale structure due to polymer chain length and water
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5395e2dd7d3cddb1b6f6af2c3f4f24
https://doi.org/10.1002/jps.22204
https://doi.org/10.1002/jps.22204
Autor:
Igor Ivanisevic, Stephen R. Byrn, David Engers, Jonathan Jimenez-Novoa, Ann Newman, Cheryl Campbell, Philip Gent, John Thomson, Jing Teng, Alison Templeton, Stuart Hossack
Publikováno v:
Journal of Pharmaceutical Sciences. 99:3901-3922
A solid-state approach to enable compounds in preclinical development is used by identifying an amorphous solid dispersion in a simple formulation to increase bioavailability. Itraconazole (ITZ) was chosen as a model crystalline compound displaying p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f331610905bf23b9e4af3173d085fd5f
https://doi.org/10.1002/jps.22233
https://doi.org/10.1002/jps.22233
Publikováno v:
Journal of Pharmaceutical Sciences. 97:4840-4856
Recognizing limitations with the standard method of determining whether an amorphous API–polymer mixture is miscible based on the number of glass transition temperatures (Tg) using differential scanning calorimetry (DSC) measurements, we have devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5106013ba9fcfa19ec73d276ba39b5a
https://doi.org/10.1002/jps.21352
https://doi.org/10.1002/jps.21352
Publikováno v:
Journal of Electrostatics. 65:571-581
Binary mixtures of pharmaceutically relevant powders were investigated using dielectric spectroscopy over a frequency range of 10 −3 to 300 kHz. Two different binary mixtures were studied as a function of concentration; pseudoephedrine hydrochlorid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a9356082fdcf75d60d95db13edd501b
https://doi.org/10.1016/j.elstat.2006.12.002
https://doi.org/10.1016/j.elstat.2006.12.002
Publikováno v:
Journal of Electrostatics. 64:826-835
A test apparatus and methods used to study the influence of physical properties of pharmaceutically relevant powders and powder mixtures on triboelectric behavior during low-shear blending is described. Samples were mixed using a stainless steel blen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcac11ace33d9bb4ac4734e1384ecdf9
https://doi.org/10.1016/j.elstat.2006.02.003
https://doi.org/10.1016/j.elstat.2006.02.003
Autor:
Michael J. Pikal, Yonglai Yang, Igor Ivanisevic, Adora M. Padilla, Robin H. Bogner, David Engers
Publikováno v:
Journal of pharmaceutical sciences. 100(1)
Phase separation in amorphous freeze-dried mixtures is likely in many systems. However, suitable detection methodology has been lacking, as the classical technique, differential scanning calorimetry (DSC), relies upon detection of multiple glass tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d2e485dfdcf78d409c8e8610418ddb
https://pubmed.ncbi.nlm.nih.gov/20602453
https://pubmed.ncbi.nlm.nih.gov/20602453
Publikováno v:
Pharmaceutical Research; Oct2006, Vol. 23 Issue 10, p2333-2349, 17p