Zobrazeno 1 - 10
of 82
pro vyhledávání: '"David Engelberg"'
Autor:
Sonja C. J. H. Chua, Jianzhou Cui, Karishma Sachaphibulkij, Isabelle Siang Ling Tan, Hui Qing Tan, Hong Meng Lim, David Engelberg, Lina H. K. Lim
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Influenza A virus is a respiratory virus that can cause complications such as acute bronchitis and secondary bacterial pneumonia. Drug therapies and vaccines are available against influenza, albeit limited by drug resistance and the non-univ
Externí odkaz:
https://doaj.org/article/da3b4fb358054634ad3e30135eb6c9a3
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Annually, the influenza virus causes 500,000 deaths worldwide. Influenza-associated mortality and morbidity is especially high among the elderly, children, and patients with chronic diseases. While there are antivirals available against influenza, su
Externí odkaz:
https://doaj.org/article/706a1d2e368549d6a680df0eea047193
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237540 (2020)
The yeast MAP kinase Hog1 pathway activates transcription of several hundreds genes. Large-scale gene expression and DNA binding assays suggest that most Hog1-induced genes are regulated by the transcriptional activators Msn2/4, Hot1 and Sko1. These
Externí odkaz:
https://doaj.org/article/1e78678b231a4586b4cae7e8556d14a7
Publikováno v:
Cells, Vol 9, Iss 1, p 129 (2020)
Unique characteristics distinguish extracellular signal-regulated kinases (Erks) from other eukaryotic protein kinases (ePKs). Unlike most ePKs, Erks do not autoactivate and they manifest no basal activity; they become catalysts only when dually phos
Externí odkaz:
https://doaj.org/article/b7f394d8f9834918b2d8f6d7b362418c
Publikováno v:
Pharmaceuticals, Vol 12, Iss 4, p 147 (2019)
Ninety years after the discovery of the virus causing the influenza disease, this malady remains one of the biggest public health threats to mankind. Currently available drugs and vaccines only partially reduce deaths and hospitalizations. Some of th
Externí odkaz:
https://doaj.org/article/27ff15a57c884f92a9bde5f1fb2b2d19
Publikováno v:
BioTechniques, Vol 36, Iss 6, Pp 933-936 (2004)
Externí odkaz:
https://doaj.org/article/13fe2eb8402b44e1a6adc7dfd9607735
Publikováno v:
BioTechniques, Vol 28, Iss 3, Pp 552-560 (2000)
The expression of foreign proteins in Saccharomyces cerevisiae is a powerful tool for basic research and the biotechnological industry. In spite of the potential of S. cerevisiae, only a few useful expression vectors have been developed for this yeas
Externí odkaz:
https://doaj.org/article/a5f1de5afa5d418c84380ca9df40efcc
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44749 (2012)
Many protein kinases require phosphorylation at their activation loop for induction of catalysis. Mitogen-activated protein kinases (MAPKs) are activated by a unique mode of phosphorylation, on neighboring Tyrosine and Threonine residues. Whereas man
Externí odkaz:
https://doaj.org/article/2d1b40418d6346c7b1766b1b9ab3ea63
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6c1c4f6c67067502023b73a47611de0
https://doi.org/10.1096/fasebj.2022.36.s1.r3513
https://doi.org/10.1096/fasebj.2022.36.s1.r3513
Autor:
Rotem Lange, Allan Bar-Sinai, Adi Salzberg, Ze'ev Paroush, Shaked Bar-Cohen, Tatyana Kushnir, David Engelberg, Navit Mooshayef, Helit Rozen
Publikováno v:
Genetics. 214:109-120
Excessive RTK signaling, often caused by activating mutations in Ras, Raf and/or MEK, occurs in most human tumors. Intriguingly, confirmed cancer-driver mutations in the downstream effector kinase, ERK, have not been reported. To test if... Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c16c338521ea040fb0d3440080c2f9
https://doi.org/10.1534/genetics.119.302794
https://doi.org/10.1534/genetics.119.302794