Výsledky vyhledávání - "David E. Zakur"

A novel endpoint for the assessment of chemotherapy-induced peripheral neuropathy in rodents: biomechanical properties of peripheral nerve

Autor: Chedo M. Bagi, David E. Zakur, Chris J. Somps, Chang-Ning Liu, Ahmed M. Shoieb, Edwin Berryman, Ingrid D. Pardo, Jon C. Cook, Magalie Boucher

Publikováno v: Journal of Applied Toxicology. 38:193-200

Chemotherapy-induced peripheral neuropathy (CiPN) is a frequent adverse effect in patients and a leading safety consideration in oncology drug development. Although behavioral assessment and microscopic examination of the nerves and dorsal root gangl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9129a49515d8e77c803ddd2e8cb907
https://doi.org/10.1002/jat.3513

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Antiresorptive and Anabolic Bone Therapy Does not Improve Weight Bearing Capacity and Bone Strength in OA Rats

Autor: Edwin Berryman, Isabela B Bagi, Cedo M. Bagi, David E. Zakur, Catharine J. Andresen, Chang-Ning Liu

Publikováno v: Open Journal of Orthopedics and Rheumatology. 1:004-011

Objective: This manuscript reports the outcomes of medial meniscectomy (MM) surgery on cartilage and cortical bone strength and the reaction of cartilage and bone to intensive treatment with antiresorptive (zoledronate) and anabolic bone (PTH) therap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8717b2d3f976f57323209030f3d1435b
https://doi.org/10.17352/ojor.000002

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Effect of antiresorptive and anabolic bone therapy on development of osteoarthritis in a posttraumatic rat model of OA

Autor: Edwin Berryman, David E. Zakur, Catharine J. Andresen, Cedo M. Bagi, Dean Wilkie

Publikováno v: Arthritis Research & Therapy

Introduction Osteoarthritis (OA) is a leading cause of disability, but despite the high unmet clinical need and extensive research seeking dependable therapeutic interventions, no proven disease-modifying treatment for OA is currently available. Due

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2895c02e6d6e50bae31a25281ab24e0
http://europepmc.org/articles/PMC4635572

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Correlation between μCT imaging, histology and functional capacity of the osteoarthritic knee in the rat model of osteoarthritis

Autor: Dean Wilkie, Catharine J. Andresen, David E. Zakur, Edwin Berryman, Cedo M. Bagi

Publikováno v: Journal of Translational Medicine

Background To acquire the most meaningful understanding of human arthritis, it is essential to select the disease model and methodology translatable to human conditions. The primary objective of this study was to evaluate a number of analytic techniq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6151332b4baa4d7f6fd875e5b824c2c5
https://doi.org/10.1186/s12967-015-0641-7

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