Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote.

Autor: Jonathan A Eisen, Robert S Coyne, Martin Wu, Dongying Wu, Mathangi Thiagarajan, Jennifer R Wortman, Jonathan H Badger, Qinghu Ren, Paolo Amedeo, Kristie M Jones, Luke J Tallon, Arthur L Delcher, Steven L Salzberg, Joana C Silva, Brian J Haas, William H Majoros, Maryam Farzad, Jane M Carlton, Roger K Smith, Jyoti Garg, Ronald E Pearlman, Kathleen M Karrer, Lei Sun, Gerard Manning, Nels C Elde, Aaron P Turkewitz, David J Asai, David E Wilkes, Yufeng Wang, Hong Cai, Kathleen Collins, B Andrew Stewart, Suzanne R Lee, Katarzyna Wilamowska, Zasha Weinberg, Walter L Ruzzo, Dorota Wloga, Jacek Gaertig, Joseph Frankel, Che-Chia Tsao, Martin A Gorovsky, Patrick J Keeling, Ross F Waller, Nicola J Patron, J Michael Cherry, Nicholas A Stover, Cynthia J Krieger, Christina del Toro, Hilary F Ryder, Sondra C Williamson, Rebecca A Barbeau, Eileen P Hamilton, Eduardo Orias

Publikováno v: PLoS Biology, Vol 4, Iss 9, p e286 (2006)

The ciliate Tetrahymena thermophila is a model organism for molecular and cellular biology. Like other ciliates, this species has separate germline and soma functions that are embodied by distinct nuclei within a single cell. The germline-like micron

Externí odkaz: https://doaj.org/article/05012f5a3b544655a50cce2f034ce46a

Cytoplasmic dynein-2: from molecules to human diseases

Autor: Jonathan P. D’Amico, Vidyalakshmi Rajagopalan, David E. Wilkes

Publikováno v: Frontiers in Biology. 8:119-126

The dynein motor protein family is involved in a wide variety of functions in eukaryotic cells. The axonemal dynein class and cytoplasmic dynein-1 subclass have been well characterized. However, the cytoplasmic dynein-2 subclass of the family has onl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8bb41114f9f2f9b7c160c1148df7666
https://doi.org/10.1007/s11515-012-1242-y

Dynein light chain family inTetrahymena thermophila

Autor: Ekaterina Kniazeva, David E. Wilkes, Alice E. Wiedeman, Vidyalakshmi Rajagopalan, Clarence W. C. Chan, David J. Asai

Publikováno v: Cell Motility and the Cytoskeleton. 64:82-96

Dyneins are large protein complexes that produce directed movement on microtubules. In situ, dyneins comprise combinations of heavy, intermediate, light-intermediate, and light chains. The light chains regulate the locations and activities of dyneins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d52f282b84af171cf9afc72eb83b32
https://doi.org/10.1002/cm.20165

Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control

Autor: Michael W. Mather, Donna Cassidy-Hanley, Ujjwal Kumar, Hong Cai, Harry W. Dickerson, Chad G. Pearson, Justin Johnson, Jessica B. Hostetler, Jianying Gu, Dhanasekaran Shanmugam, Yufeng Wang, Yves Van de Peer, Irtisha Singh, David S. Roos, Martin Wu, Vidyalakshmi Rajagopalan, Linda Hannick, Vinita Joardar, Robert S. Coyne, Theodore G. Clark, Diana Radune, R. C. Findly, David E. Wilkes, Jonathan H. Badger, David J. Asai, Daniel Brami, Milton H. Saier, Akhil B. Vaidya, Cindy Martens

Publikováno v: Genome Biology
Coyne, Robert S; Hannick, Linda; Shanmugam, Dhanasekaran; Hostetler, Jessica B; Brami, Daniel; Joardar, Vinita S; et al.(2011). Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control. Genome Biology, 12(10), R100. doi: http://dx.doi.org/10.1186/gb-2011-12-10-r100. Retrieved from: http://www.escholarship.org/uc/item/94n9s295
GENOME BIOLOGY

Background Ichthyophthirius multifiliis, commonly known as Ich, is a highly pathogenic ciliate responsible for 'white spot', a disease causing significant economic losses to the global aquaculture industry. Options for disease control are extremely l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2b34d7f4182bccb2f43c64ec9737a6
https://pubmed.ncbi.nlm.nih.gov/22004680

Analysis of properties of cilia using Tetrahymena thermophila

Autor: Vidyalakshmi, Rajagopalan, Elizabeth O, Corpuz, Mark J, Hubenschmidt, Caroline R, Townsend, David J, Asai, David E, Wilkes

Publikováno v: Methods in molecular biology (Clifton, N.J.). 586

Cilia and eukaryotic flagella are important structures required for the motility of cells, the movement of medium across the surfaces of cells, and the connections between the receptor and synthetic portions of sensory cells. The axoneme forms the cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5665c923584bfb572fca067b6530eee4
https://pubmed.ncbi.nlm.nih.gov/19768437