Zobrazeno 1 - 2
of 2
pro vyhledávání: '"David E. Shubert"'
Autor:
Moheswar Sharma, Barbara P. McGarrigle, Jennifer Lewis, James R. Olson, Minoti Sharma, Diane P. Bofinger, David E. Shubert
Publikováno v:
Chemico-Biological Interactions. 146:237-249
Although long-term tamoxifen therapy is associated with increased risk of endometrial cancer, little is known about the ability of endometrial tissue to biotransform tamoxifen to potentially reactive intermediates, capable of forming DNA adducts. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be7b37ea9e07d251c79323559510e66
https://doi.org/10.1016/j.cbi.2003.06.002
https://doi.org/10.1016/j.cbi.2003.06.002
Autor:
Minoti Sharma, Chad M. Vezina, James R. Olson, David E. Shubert, Moheswar Sharma, Diane P. Bofinger, Kerry J. Rodabaugh, Barbara P. McGarrigle
Publikováno v:
Biochemical and Biophysical Research Communications. 307:157-164
Fresh human endometrial explants were incubated for 24h at 37 degrees C with either tamoxifen (10-100 micro M) or the vehicle (0.1% ethanol). Three metabolites namely, alpha-hydroxytamoxifen, 4-hydroxytamoxifen, and N-desmethyltamoxifen were identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e210558d64c9df061b62d3d08bb42986
https://doi.org/10.1016/s0006-291x(03)01134-3
https://doi.org/10.1016/s0006-291x(03)01134-3