Zobrazeno 1 - 5
of 5
pro vyhledávání: '"David E. Selk"'
Publikováno v:
Neuropharmacology. 38:1299-1306
NADPH-d (nicotinamide-adenine dinucleotide phosphate-diaphorase) neurons are thought to migrate improperly during development in the brains of schizophrenic patients. This enzyme is a nitric oxide synthase (NOS). Nitric oxide (NO) is known to affect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297b6aef0149a3209fcb6138c37ecb7a
https://doi.org/10.1016/s0028-3908(99)00041-6
https://doi.org/10.1016/s0028-3908(99)00041-6
Autor:
Fernando Camacho, Fink David M, Olsen Gordon Edward, Lawrence L. Martin, Wayne W. Petko, Richard C. Effland, Hugo M. Vargas, Craig P. Smith, David E. Selk, Douglas K. Rush, Klein Joseph Thomas, Peter Allen Nemoto, Larry Davis, Gina M. Bores, James T. Winslow
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:157-162
A series of carbamate analogs of besipirdine (HP 749) was synthesized as potential agents with enhanced cholinomimetic properties for the treatment of Alzheimer's disease. Compound 5a (P10358, 1-[3-fluoro-4-pyridinyl)amino]-3-methyl-1H-indol-5-yl met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a6f4a2e14f8942baf3115f4bd52456a
https://doi.org/10.1016/s0960-894x(96)00592-6
https://doi.org/10.1016/s0960-894x(96)00592-6
Autor:
Richard C. Effland, Kurys Barbara E, Fink David M, Francis P. Huger, Douglas K. Rush, Gina M. Bores, David E. Selk
Publikováno v:
ChemInform. 26
A series of 5-amino-5,6,7,8-tetrahydroquinolinones was designed and synthesized as acetylcholinesterase inhibitors. The compounds are related to hyperzine A, a naturally occurring cholinesterase inhibitor. They inhibit acetylcholinesterase in vitro,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3d08385cb69344524b489df43813432
https://doi.org/10.1002/chin.199552146
https://doi.org/10.1002/chin.199552146
Autor:
Klein Joseph Thomas, Craig P. Smith, Fink David M, Wayne W. Petko, Richard C. Effland, Douglas K. Rush, Peter Allen Nemoto, Fernando Camacho, Olsen Gordon Edward, Larry Davis, Gina M. Bores, James T. Winslow, David E. Selk, Hugo M. Vargas, Lawrence L. Martin
Publikováno v:
ChemInform. 28
A series of carbamate analogs of besipirdine (HP 749) was synthesized as potential agents with enhanced cholinomimetic properties for the treatment of Alzheimer's disease. Compound 5a (P10358, 1-[3-fluoro-4-pyridinyl)amino]-3-methyl-1H-indol-5-yl met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41000ba1c31656f9c84fb42e02ee999a
https://doi.org/10.1002/chin.199720130
https://doi.org/10.1002/chin.199720130
Autor:
Claude Oberlander, Fink David M, D. Cunningham, David E. Selk, Gina M. Bores, Eva Marie DiLeo, Karen M. Brooks, Anne Dekeyne, Hugo M. Vargas, James T. Winslow, Fernando Camacho, Larry Davis, Andrew Giovanni, Craig P. Smith, Lily Zhou, Mary Li, Douglas J. Turk, Douglas K. Rush
Publikováno v:
Alzheimer Disease ISBN: 9781461286608
Alzheimer’s disease (AD) is a complex and multifaceted neurodegenerative disease characterized by cognitive and behavioral abnormalities. The primary cognitive deficit has been correlated with extensive cholinergic dysfunction and the efficacy of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78da4f39c0cda4f567db083accd61316
https://doi.org/10.1007/978-1-4612-4116-4_37
https://doi.org/10.1007/978-1-4612-4116-4_37
