Zobrazeno 1 - 10
of 49
pro vyhledávání: '"David E. Seitz"'
Publikováno v:
Tetrahedron Letters. 36:1413-1416
A series of doxorubicin enaminomalonyl-β-alanine derivatives1a-e has been synthesized as potential drug-linker domains of an antibody drug conjugate. The release of doxorubicin from these enamide derivatives under acidic and neutral conditions has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e2df61be4aa0d950637acec476fccd3
https://doi.org/10.1016/0040-4039(95)00019-9
https://doi.org/10.1016/0040-4039(95)00019-9
Autor:
Issa S. Moody, Patrick C. Sims, Gregory A. Weiss, Brad L. Corso, David E. Seitz, Steven R. Hunt, Larry C. Blaszczak, Philip G. Collins, Yongki Choi
The dynamic processivity of individual T4 lysozyme molecules was monitored in the presence of either linear or cross-linked peptidoglycan substrates. Single-molecule monitoring was accomplished using a novel electronic technique in which lysozyme mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde13b1b8c271fbd2d216804e2c308b6
https://europepmc.org/articles/PMC3271187/
https://europepmc.org/articles/PMC3271187/
Publikováno v:
ChemInform. 23
This article presents the position-specific introduction of substituents onto substituted phenolic rings via electrophilic destannylation of trialkylstannyl derivatives of β-[N,N-dialkylamino]ethoxybenzenes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4115fb0314334ef62d0b947b7633ad62
https://doi.org/10.1002/chin.199227227
https://doi.org/10.1002/chin.199227227
Publikováno v:
ChemInform. 26
A series of doxorubicin enaminomalonyl-β-alanine derivatives1a-e has been synthesized as potential drug-linker domains of an antibody drug conjugate. The release of doxorubicin from these enamide derivatives under acidic and neutral conditions has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22732eb101cec459ed5b798b145ad821
https://doi.org/10.1002/chin.199527292
https://doi.org/10.1002/chin.199527292
Autor:
Yei Mei Peng, Gerald B. Grindey, Marta Hamilton, Thomas M. McCloskey, Charles W. Taylor, Denise J. Roe, David S. Alberts, David E. Seitz, Patricia M. Plezia, Monika Matzner
Publikováno v:
JNCI Journal of the National Cancer Institute. 84:1798-1802
BACKGROUND Sulofenur is a diarylsulfonylurea with demonstrated antitumor activity in patients with advanced epithelial ovarian cancer refractory to standard chemotherapy. The dose-limiting toxic effects observed in phase I clinical trials have been a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b87fad6282ec167686fc205eb1db0f4
https://doi.org/10.1093/jnci/84.23.1798
https://doi.org/10.1093/jnci/84.23.1798
Publikováno v:
Heteroatom Chemistry. 2:583-586
This article presents the position-specific introduction of substituents onto substituted phenolic rings via electrophilic destannylation of trialkylstannyl derivatives of β-[N,N-dialkylamino]ethoxybenzenes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::627afe7ec71f22e3aa6ba956737192c1
https://doi.org/10.1002/hc.520020513
https://doi.org/10.1002/hc.520020513
Autor:
David E. Seitz, Joel Picus, C. Calley, Kristen N. Ganjoo, Patrick J. Loehrer, Bryan P. Schneider, Cindy Stoner, Farid Fata
Publikováno v:
Oncology. 65(3)
Objective: To determine the response rate, duration of response and survival with weekly gemcitabine plus docetaxel in metastatic or unresectable pancreatic cancer. Methods: Forty patients were enrolled, and 38 patients were evaluable for survival an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2639b228a0131d82780596e8c107be6
https://pubmed.ncbi.nlm.nih.gov/14657595
https://pubmed.ncbi.nlm.nih.gov/14657595
Autor:
Sonal P, Sanghani, Sara K, Quinney, Tyler B, Fredenburg, Zejin, Sun, Wilhelmina I, Davis, Daryl J, Murry, Oscar W, Cummings, David E, Seitz, William F, Bosron
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 9(13)
The purpose is to develop new analytical methods to study the expression profile of CPT-11 carboxylesterases and topoisomerase I in colon tumor samples and understand the impact of their expression on CPT-11 metabolism in chemotherapy.We investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8243e939fb18876a74b77c67af466f8c
https://pubmed.ncbi.nlm.nih.gov/14581373
https://pubmed.ncbi.nlm.nih.gov/14581373
Autor:
Clet, Niyikiza, Sharyn D, Baker, David E, Seitz, Jackie M, Walling, Katrina, Nelson, James J, Rusthoven, Sally P, Stabler, Paolo, Paoletti, A Hilary, Calvert, Robert H, Allen
Publikováno v:
Molecular cancer therapeutics. 1(7)
The purpose of this study was to identify predictive factors for severe toxicity caused by antifolate-chemotherapy using pemetrexed (ALIMTA, LY231514), as a model. Data on potential predictive factors for severe toxicity from pemetrexed were collecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d48d4865cd35cec7c13b58e9f86f3b82
https://pubmed.ncbi.nlm.nih.gov/12479273
https://pubmed.ncbi.nlm.nih.gov/12479273
Publikováno v:
Investigational New Drugs. 11:203-205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966473b38b1af277b19381b5b88db978
https://doi.org/10.1007/bf00874156
https://doi.org/10.1007/bf00874156