Zobrazeno 1 - 10
of 23
pro vyhledávání: '"David E. Scherrer"'
Autor:
Xuntian Jiang, Rohini Sidhu, Forbes D. Porter, Nicole M. Yanjanin, Anneliese O. Speak, Danielle Taylor te Vruchte, Frances M. Platt, Hideji Fujiwara, David E. Scherrer, Jessie Zhang, Dennis J. Dietzen, Jean E. Schaffer, Daniel S. Ory
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 7, Pp 1435-1445 (2011)
Niemann-Pick type C1 (NPC1) disease is a rare, progressively fatal neurodegenerative disease for which there are no FDA-approved therapies. A major barrier to developing new therapies for this disorder has been the lack of a sensitive and noninvasive
Externí odkaz:
https://doaj.org/article/fd2be7e10ce9455887cd6cba09bdf241
Autor:
Delphine L Chen, Howard J Huang, Derek E Byers, Adrian Shifren, Bryan Belikoff, Jacquelyn T Engle, Elizabeth Arentson, Debra Kemp, Sharon Phillips, David E Scherrer, Hideji Fujiwara, Katherine J Spayd, Frank J Brooks, Richard A Pierce, Mario Castro, Warren Isakow
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191783 (2018)
BACKGROUND:Anti-inflammatory drug development efforts for lung disease have been hampered in part by the lack of noninvasive inflammation biomarkers and the limited ability of animal models to predict efficacy in humans. We used 18F-fluorodeoxyglucos
Externí odkaz:
https://doaj.org/article/eab584034270471c847af99e2a775ed8
Autor:
Daniel S. Ory, Maria S. Remedi, Alexis N. Harris, Jean E. Schaffer, Jana Mahadevan, Zeno Lavagnino, Christopher L. Holley, Fumihiko Urano, Hideji Fujiwara, Kelly D. Pyles, David E. Scherrer, Rohini Sidhu, David W. Piston, Stanley Ching-Cheng Huang, Jiyeon Lee, Jessie Zhang
Publikováno v:
Journal of Clinical Investigation. 126:4616-4625
Small nucleolar RNAs (snoRNAs) are non-coding RNAs that form ribonucleoproteins to guide covalent modifications of ribosomal and small nuclear RNAs in the nucleus. Recent studies have also uncovered additional non-canonical roles for snoRNAs. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a500813cb940ae16ace2e2b742db5887
https://doi.org/10.1172/jci88069
https://doi.org/10.1172/jci88069
Autor:
Howard J. Huang, David E. Scherrer, Derek E. Byers, Adrian Shifren, Sharon Phillips, Delphine L. Chen, Elizabeth Arentson, Katherine J. Spayd, Debra Kemp, Jacquelyn T. Engle, Richard A. Pierce, Mario Castro, Bryan G Belikoff, Frank J. Brooks, Warren Isakow, Hideji Fujiwara
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 2, p e0191783 (2018)
PLoS ONE, Vol 13, Iss 2, p e0191783 (2018)
BACKGROUND:Anti-inflammatory drug development efforts for lung disease have been hampered in part by the lack of noninvasive inflammation biomarkers and the limited ability of animal models to predict efficacy in humans. We used 18F-fluorodeoxyglucos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f86eb91f9c8600551d6badffba7a44
http://europepmc.org/articles/PMC5802889
http://europepmc.org/articles/PMC5802889
Autor:
Douglas F. Covey, Sarah E. Gale, Howard L. Brockman, Emily J. Westover, Nicole Dudley, Daniel S. Ory, Rhoderick E. Brown, Sean Merlin, David E. Scherrer, Kathiresan Krishnan, Xiuhong Zhai, Jean E. Schaffer, Xianlin Han, Paul H. Schlesinger
Publikováno v:
Journal of Biological Chemistry. 284:1755-1764
Side chain oxysterols exert cholesterol homeostatic effects by suppression of sterol regulatory element-binding protein maturation and promoting degradation of hydroxymethylglutaryl-CoA reductase. To examine whether oxysterol-membrane interactions co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7179b027b242415105a7685185586196
https://doi.org/10.1074/jbc.m807210200
https://doi.org/10.1074/jbc.m807210200
Autor:
Sara M. Peyrot, Laurel Mydock-McGrane, Rajat Rohatgi, Andrew P. Jallouk, Sigrid Nachtergaele, Daniel S. Ory, Hideji Fujiwara, David E. Scherrer, Paul H. Schlesinger, Douglas F. Covey, Giovanni Luchetti
Publikováno v:
The Journal of biological chemistry. 289(16)
Oxysterols, oxidized metabolites of cholesterol, are endogenous small molecules that regulate lipid metabolism, immune function, and developmental signaling. Although the cell biology of cholesterol has been intensively studied, fundamental questions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32ec1fedbe57e1a2c3d226f315f1e00
https://pubmed.ncbi.nlm.nih.gov/24596093
https://pubmed.ncbi.nlm.nih.gov/24596093
Autor:
Dana R. Abendschein, Michael J. Scott, David E. Scherrer, Jon N. Marsh, Christopher S. Hall, Samuel A. Wickline, Gregory M. Lanza
Publikováno v:
Investigative Radiology. 35:227-234
RATIONALE AND OBJECTIVES Molecular imaging with targeted contrast agents enables tissues to be distinguished by detecting specific cell-surface receptors. In the present study, a ligand-targeted acoustic nanoparticle system is used to identify angiop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483e2d987fa311c0da26b80e7fe5a34b
https://doi.org/10.1097/00004424-200004000-00003
https://doi.org/10.1097/00004424-200004000-00003
Autor:
Pamela De Ciechi, Paul R. Eisenberg, Eser Tolunay, James St. Pierre, Kamala Tamirisa, David E. Scherrer, Lu-ying Yang, Dana R. Abendschein
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 19:2263-2268
Abstract —Intravenous infusion of recombinant tissue factor pathway inhibitor (rTFPI) for 24 hours decreases neointimal thickening and luminal stenosis 1 month after balloon-induced injury to the carotid arteries in minipigs. This study was designe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769aaaac6c78d394ad90828484522c79
https://doi.org/10.1161/01.atv.19.9.2263
https://doi.org/10.1161/01.atv.19.9.2263
Autor:
David E. Scherrer, Dana R. Abendschein, R. G. Walsh, J. St Pierre, Lu-ying Yang, J. M. Lasala
Publikováno v:
Coronary Artery Disease. 10:327-334
BACKGROUND Prolonged intravenous infusions of recombinant tissue factor pathway inhibitor (rTFPI) have been shown to attenuate markedly neointimal formation and stenosis after balloon-induced injury to the carotid arteries in minipigs. DESIGN Because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23dddf23897748751f0390cb99b732df
https://doi.org/10.1097/00019501-199907000-00009
https://doi.org/10.1097/00019501-199907000-00009
Autor:
Jessie Zhang, Hideji Fujiwara, Frances M. Platt, Jean E. Schaffer, Danielle Taylor te Vruchte, Daniel S. Ory, Anneliese O. Speak, Dennis J. Dietzen, Rohini Sidhu, Forbes D. Porter, David E. Scherrer, Nicole M. Yanjanin, Xuntian Jiang
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 7, Pp 1435-1445 (2011)
Niemann-Pick type C1 (NPC1) disease is a rare, progressively fatal neurodegenerative disease for which there are no FDA-approved therapies. A major barrier to developing new therapies for this disorder has been the lack of a sensitive and noninvasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454616287882ac678ff7bc77fd62eede
http://ora.ox.ac.uk/objects/uuid:f9c53a0f-e7e4-43f7-9646-1f6730f881da
http://ora.ox.ac.uk/objects/uuid:f9c53a0f-e7e4-43f7-9646-1f6730f881da