Zobrazeno 1 - 10
of 41
pro vyhledávání: '"David E. Place"'
Autor:
David E. Place, R. K. Subbarao Malireddi, Jieun Kim, Peter Vogel, Masahiro Yamamoto, Thirumala-Devi Kanneganti
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The innate immune system and inflammation modulate bone homeostasis through complex regulation of bone remodelling cells including osteoblasts and osteoclasts. Here, the authors show that the type I interferon pathway and guanylate binding proteins f
Externí odkaz:
https://doaj.org/article/fea52b57d5b54778a319077014717dd0
Autor:
Rachel L. Markley, Katherine H. Restori, Bhuvana Katkere, Sarah E. Sumner, McKayla J. Nicol, Anastasia Tyryshkina, Shaneice K. Nettleford, David R. Williamson, David E. Place, Kalyan K. Dewan, Ashley E. Shay, Bradley A. Carlson, Santhosh Girirajan, K. Sandeep Prabhu, Girish S. Kirimanjeswara
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The essential micronutrient Selenium (Se) is co-translationally incorporated as selenocysteine into proteins. Selenoproteins contain one or more selenocysteines and are vital for optimum immunity. Interestingly, many pathogenic bacteria utilize Se fo
Externí odkaz:
https://doaj.org/article/99bbee9a907a441aa3a38efdca6ca9f1
Autor:
David E. Place, Shelbi Christgen, Shraddha Tuladhar, Peter Vogel, R. K. Subbarao Malireddi, Thirumala-Devi Kanneganti
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
BurkholderiaBurkholderia thailandensisB. thailandensis
Externí odkaz:
https://doaj.org/article/181c90460015411da2df0e7ca0072d4d
Autor:
Shelbi Christgen, Min Zheng, Sannula Kesavardhana, Rajendra Karki, R. K. Subbarao Malireddi, Balaji Banoth, David E. Place, Benoit Briard, Bhesh Raj Sharma, Shraddha Tuladhar, Parimal Samir, Amanda Burton, Thirumala-Devi Kanneganti
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Programmed cell death plays crucial roles in organismal development and host defense. Recent studies have highlighted mechanistic overlaps and extensive, multifaceted crosstalk between pyroptosis, apoptosis, and necroptosis, three programmed cell dea
Externí odkaz:
https://doaj.org/article/d7c42e6461044efd914472bb054228b9
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/0f54699dc954472ca0c8f19f023014b8
Publikováno v:
Microorganisms, Vol 9, Iss 5, p 973 (2021)
Francisella tularensis (Ft) is a Gram-negative, facultative intracellular coccobacillus that is the etiological agent of tularemia. Interestingly, the disease tularemia has variable clinical presentations that are dependent upon the route of infectio
Externí odkaz:
https://doaj.org/article/fabaf6de62a14343873545fb11de1836
Publikováno v:
The Journal of Immunology. 207:115-124
Cellular stress can induce cytoplasmic ribonucleoprotein complexes called stress granules that allow the cells to survive. Stress granules are also central to cellular responses to infections, in which they can act as platforms for viral sensing or m
Publikováno v:
Current Opinion in Microbiology
Highlights • Cells exposed to TLR ligands and cytokines during infection activate PANoptosis. • RIPK1-dependent PANoptosome is formed when cell survival signaling is inhibited. • Influenza A virus Z-RNAs bind and activate ZBP1, promoting PANopt
Publikováno v:
Current Opinion in Immunology. 67:95-105
The innate immune system, the first line of defense against pathogens and host tissue damage, initiates pro-inflammatory responses which, when dysregulated, promote inflammation to drive a broad range of autoimmune diseases. Immunomodulatory therapie
Autor:
Min Zheng, Shelbi Christgen, Masahiro Yamamoto, Thirumala-Devi Kanneganti, David E. Place, Benoit Briard
Publikováno v:
Eur J Immunol
The upregulation of interferon (IFN)-inducible GTPases in response to pathogenic insults is vital to host defense against many bacterial, fungal, and viral pathogens. Several IFN-inducible GTPases play key roles in mediating inflammasome activation a