Zobrazeno 1 - 10
of 21
pro vyhledávání: '"David E. Joyce"'
Autor:
Rashmi Sood, Hartmut Weiler, Jean-François Dhainaut, David E. Joyce, S. Betty Yan, John T. Brandt, Bryce A. Kerlin, Bruce R. Basson, Berend Isermann
Publikováno v:
Blood. 102:3085-3092
Sepsis is associated with systemic inflammation, coagulopathy, and disrupted protein C (PC) pathway function. The effect of prothrombotic polymorphism, factor V Leiden (Arg506Gln; FV Leiden), was examined in a large clinical trial (PROWESS) of severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160c70f5f3127f47c47c7f5d89424a1e
https://doi.org/10.1182/blood-2003-06-1789
https://doi.org/10.1182/blood-2003-06-1789
Autor:
David E. Joyce
Publikováno v:
Seminars in Cerebrovascular Diseases and Stroke. 2:151-158
Risk factors for cancer-related ischemic stroke are difficult to discern from the traditional risk factors for atheroembolic disorders. Certain hematologic and oncologic malignancies predispose to ischemic stroke. However, contributing pathophysiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d41478d540f5cc69bb322e53e939524
https://doi.org/10.1053/scds.2002.123670
https://doi.org/10.1053/scds.2002.123670
Publikováno v:
Journal of Biological Chemistry. 276:11199-11203
Human protein C is a natural anticoagulant factor, and a recombinant activated form of the molecule (rhAPC) is completing clinical evaluation for treatment of severe sepsis. Because of the pathophysiologic role of endothelial dysfunction in severe in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731f21cad3095cd1784011a9d005560a
https://doi.org/10.1074/jbc.c100017200
https://doi.org/10.1074/jbc.c100017200
Publikováno v:
Blood. 90:1893-1901
The proteolytically activated thrombin receptor (TR) is expressed by T lymphocytes, which suggests that thrombin may modulate T-cell activation at sites of hemostatic stress. We examined the relationship between TR function and T-cell activation in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8db87b48977df35f9db38488c0012d6
https://doi.org/10.1182/blood.v90.5.1893
https://doi.org/10.1182/blood.v90.5.1893
Autor:
David E. Joyce
Publikováno v:
Current drug targets. 8(4)
The host inflammatory response is activated in both cancer and infection. This includes enhanced production of acute phase reactants, involvement of coagulation and inflammation and the potential for systemic effects. This overview will identify the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c941112c68c04c7c4879e61e8a5c9ebc
https://pubmed.ncbi.nlm.nih.gov/17430125
https://pubmed.ncbi.nlm.nih.gov/17430125
Autor:
David E, Joyce
Publikováno v:
Current drug targets. 8(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f0a349f0dc87d986641be7e577354c8
https://pubmed.ncbi.nlm.nih.gov/17430118
https://pubmed.ncbi.nlm.nih.gov/17430118
Publikováno v:
AIP Conference Proceedings.
All metrology tools must make a trade‐off between data quality and wafer throughput. Moreover, most X‐ray metrology may be performed on regions inside the scribe lines. This paper discusses the appropriate choices of trade‐offs for throughput,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0729214cb79d5a2cd6e9a66da1acab70
https://doi.org/10.1063/1.2063026
https://doi.org/10.1063/1.2063026
Publikováno v:
Critical care medicine. 32
Objective: To give an overview of leukocyte and endothelial cell interactions in sepsis and to explore the role of the protein C pathway in modulating the innate immune response via its anti-inflammatory properties. Data Source: Novel in vitro data a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a98427250b24f48533d4fc221c6b0a
https://pubmed.ncbi.nlm.nih.gov/15118531
https://pubmed.ncbi.nlm.nih.gov/15118531
Publikováno v:
AIP Conference Proceedings.
The timely identification of defects can lead to increased yields and significant cost savings in wafer production. X‐ray topography (XRT) is recognized as being a powerful tool for directly imaging defects in single crystals, such as semiconductor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebd220d18953d0ff9aa3e3bd9ea4b1d3
https://doi.org/10.1063/1.1622483
https://doi.org/10.1063/1.1622483
Autor:
Brian W. Grinnell, David E. Joyce
Publikováno v:
Critical care medicine. 30
Objective: To review the anti-inflammatory and anti-apoptotic properties of drotrecogin alfa (activated) (recombinant human activated protein C), emphasizing its modulatory effects on endothelial nuclear factor-KB. We propose a broad anti-inflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182595a358f426948ff223d5cdb33669
https://pubmed.ncbi.nlm.nih.gov/12004250
https://pubmed.ncbi.nlm.nih.gov/12004250