Zobrazeno 1 - 10
of 372
pro vyhledávání: '"David E. Housman"'
Autor:
Jill R. Crittenden, Shenyu Zhai, Magdalena Sauvage, Takashi Kitsukawa, Eric Burguière, Morgane Thomsen, Hui Zhang, Cinzia Costa, Giuseppina Martella, Veronica Ghiglieri, Barbara Picconi, Karen A. Pescatore, Ellen M. Unterwald, Walker S. Jackson, David E. Housman, S. Barak Caine, David Sulzer, Paolo Calabresi, Anne C. Smith, D. James Surmeier, Ann M. Graybiel
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105473- (2021)
CalDAG-GEFI (CDGI) is a protein highly enriched in the striatum, particularly in the principal spiny projection neurons (SPNs). CDGI is strongly down-regulated in two hyperkinetic conditions related to striatal dysfunction: Huntington's disease and l
Externí odkaz:
https://doaj.org/article/dcb665d27eb248cbbbad7e35d7e418a7
Autor:
Ryan J. McGinty, Franco Puleo, Anna Y. Aksenova, Julia A. Hisey, Alexander A. Shishkin, Erika L. Pearson, Eric T. Wang, David E. Housman, Claire Moore, Sergei M. Mirkin
Publikováno v:
Cell Reports, Vol 20, Iss 10, Pp 2490-2500 (2017)
Expansions of microsatellite repeats are responsible for numerous hereditary diseases in humans, including myotonic dystrophy and Friedreich’s ataxia. Whereas the length of an expandable repeat is the main factor determining disease inheritance, re
Externí odkaz:
https://doaj.org/article/0dfcf17ded7242c7a59c4d6e7f1ea13e
Autor:
Ryan G. Lim, Chris Quan, Andrea M. Reyes-Ortiz, Sarah E. Lutz, Amanda J. Kedaigle, Theresa A. Gipson, Jie Wu, Gad D. Vatine, Jennifer Stocksdale, Malcolm S. Casale, Clive N. Svendsen, Ernest Fraenkel, David E. Housman, Dritan Agalliu, Leslie M. Thompson
Publikováno v:
Cell Reports, Vol 19, Iss 7, Pp 1365-1377 (2017)
Brain microvascular endothelial cells (BMECs) are an essential component of the blood-brain barrier (BBB) that shields the brain against toxins and immune cells. While BBB dysfunction exists in neurological disorders, including Huntington’s disease
Externí odkaz:
https://doaj.org/article/a4c8006ac0ea461986232304206450ef
Autor:
Qiong Yang, Chao-Qiang Lai, Laurence Parnell, L. Adrienne Cupples, Xian Adiconis, Yueping Zhu, Peter W.F. Wilson, David E. Housman, Amanda M. Shearman, Ralph B. D'Agostino, Jose M. Ordovas
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 7, Pp 1416-1425 (2005)
High density lipoprotein cholesterol (HDL-C) is inversely associated with coronary heart disease and has a genetic component; however, linkage to HDL-C is not conclusive. Subfractions of HDL, such as HDL3-C, may be better phenotypes for linkage studi
Externí odkaz:
https://doaj.org/article/4e2476db3d7a4acb8280136da1eb4468
Publikováno v:
PLoS ONE, Vol 8, Iss 5 (2013)
Externí odkaz:
https://doaj.org/article/a8004542136d42838954625608eac118
Autor:
Al Charest, David E. Housman, Charles A. Whittaker, Rolf Pfannl, Roderick T. Bronson, Ami Raval, Abraham Boskovitz, Steve Woolfenden, Melissa Donovan, Haihao Zhu, Rolando Ruiz, Julie Lessard, Hyun Jung Jun, Jaime Acquaviva
Glioblastoma multiforme (GBM) is characterized by overexpression of epidermal growth factor receptor (EGFR) and loss of the tumor suppressors Ink4a/Arf. Efforts at modeling GBM using wild-type EGFR in mice have proven unsuccessful. Here, we present a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4682cdfba73f2ed12d5be97e13537506
https://doi.org/10.1158/0008-5472.c.6502758.v1
https://doi.org/10.1158/0008-5472.c.6502758.v1
Autor:
Al Charest, David E. Housman, Charles A. Whittaker, Rolf Pfannl, Roderick T. Bronson, Ami Raval, Abraham Boskovitz, Steve Woolfenden, Melissa Donovan, Haihao Zhu, Rolando Ruiz, Julie Lessard, Hyun Jung Jun, Jaime Acquaviva
PDF file - 96K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50b02dbbf0e057f5593c2e1efb74697
https://doi.org/10.1158/0008-5472.22389921.v1
https://doi.org/10.1158/0008-5472.22389921.v1
Autor:
Al Charest, David E. Housman, Charles A. Whittaker, Rolf Pfannl, Roderick T. Bronson, Ami Raval, Abraham Boskovitz, Steve Woolfenden, Melissa Donovan, Haihao Zhu, Rolando Ruiz, Julie Lessard, Hyun Jung Jun, Jaime Acquaviva
PDF file - 112K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815d9bca103d92c5500f66881b19ae33
https://doi.org/10.1158/0008-5472.22389903
https://doi.org/10.1158/0008-5472.22389903
Autor:
Al Charest, David E. Housman, Charles A. Whittaker, Rolf Pfannl, Roderick T. Bronson, Ami Raval, Abraham Boskovitz, Steve Woolfenden, Melissa Donovan, Haihao Zhu, Rolando Ruiz, Julie Lessard, Hyun Jung Jun, Jaime Acquaviva
PDF file - 172K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587299d8c490d2da7e28e799371570ec
https://doi.org/10.1158/0008-5472.22389915.v1
https://doi.org/10.1158/0008-5472.22389915.v1
Autor:
Al Charest, David E. Housman, Charles A. Whittaker, Rolf Pfannl, Roderick T. Bronson, Ami Raval, Abraham Boskovitz, Steve Woolfenden, Melissa Donovan, Haihao Zhu, Rolando Ruiz, Julie Lessard, Hyun Jung Jun, Jaime Acquaviva
PDF file - 278K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb13cfd6f39fc71f2a56d38fcff68c6
https://doi.org/10.1158/0008-5472.22389909.v1
https://doi.org/10.1158/0008-5472.22389909.v1