Zobrazeno 1 - 3
of 3
pro vyhledávání: '"David E. Einstein"'
Autor:
Henri Leinonen, Jianye Zhang, Laurence M. Occelli, Umair Seemab, Elliot H. Choi, Luis Felipe L.P. Marinho, Janice Querubin, Alexander V. Kolesnikov, Anna Galinska, Katarzyna Kordecka, Thanh Hoang, Dominik Lewandowski, Timothy T. Lee, Elliott E. Einstein, David E. Einstein, Zhiqian Dong, Philip D. Kiser, Seth Blackshaw, Vladimir J. Kefalov, Marcin Tabaka, Andrzej Foik, Simon M. Petersen-Jones, Krzysztof Palczewski
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Inherited retinopathies are devastating diseases that in most cases lack treatment options. Disease-modifying therapies that mitigate pathophysiology regardless of the underlying genetic lesion are desirable due to the diversity of mutations
Externí odkaz:
https://doaj.org/article/b5b9cf370c114fd1b6b378a34d01cbf7
Autor:
Marco Bassetto, Alexander V. Kolesnikov, Dominik Lewandowski, Jianying Z. Kiser, Maximilian Halabi, David E. Einstein, Elliot H. Choi, Krzysztof Palczewski, Vladimir J. Kefalov, Philip D. Kiser
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114143- (2024)
Summary: Cellular retinaldehyde-binding protein (CRALBP) supports production of 11-cis-retinaldehyde and its delivery to photoreceptors. It is found in the retinal pigment epithelium (RPE) and Müller glia (MG), but the relative functional importance
Externí odkaz:
https://doaj.org/article/536a6d5ec23043fcb00d03661c34c961
Autor:
Elliot H. Choi, Susie Suh, David E. Einstein, Henri Leinonen, Zhiqian Dong, Sriganesh Ramachandra Rao, Steven J. Fliesler, Seth Blackshaw, Minzhong Yu, Neal S. Peachey, Krzysztof Palczewski, Philip D. Kiser
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
The retinal pigment epithelium (RPE) provides vital metabolic support for retinal photoreceptor cells and is an important player in numerous retinal diseases. Gene manipulation in mice using the Cre-LoxP system is an invaluable tool for studying the
Externí odkaz:
https://doaj.org/article/9bd5b7f2aed546ab8d29ac38a52ecb52