Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David E. Condon"'
Autor:
Praveen F. Cherukuri, Melissa M. Soe, David E. Condon, Shubhi Bartaria, Kaitlynn Meis, Shaopeng Gu, Frederick G. Frost, Lindsay M. Fricke, Krzysztof P. Lubieniecki, Joanna M. Lubieniecka, Robert E. Pyatt, Catherine Hajek, Cornelius F. Boerkoel, Lynn Carmichael
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-17 (2022)
Abstract Background Clinical use of genotype data requires high positive predictive value (PPV) and thorough understanding of the genotyping platform characteristics. BeadChip arrays, such as the Global Screening Array (GSA), potentially offer a high
Externí odkaz:
https://doaj.org/article/bd22b094b3d44ee8b4105e369acbce00
Autor:
David E. Condon, Phu V. Tran, Yu-Chin Lien, Jonathan Schug, Michael K. Georgieff, Rebecca A. Simmons, Kyoung-Jae Won
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Identification of differentially methylated regions (DMRs) is the initial step towards the study of DNA methylation-mediated gene regulation. Previous approaches to call DMRs suffer from false prediction, use extreme resources, an
Externí odkaz:
https://doaj.org/article/844f63a9e4c34a6f8da4fceb6e44810e
Autor:
Apoorva Joshi, David E. Condon, Paul Zhipang Wang, Cetewayo S. Rashid, So Won Min, Sara E. Pinney, Victoria Yin
Publikováno v:
J Clin Endocrinol Metab
Context Gestational diabetes (GDM) has profound effects on the intrauterine metabolic milieu and is linked to obesity and diabetes in offspring, but the mechanisms driving these effects remain largely unknown. Alterations in DNA methylation and gene
Publikováno v:
Diabetes. 68
Background: Gestational diabetes (GDM) has profound effects on the intrauterine metabolic milieu, induces marked abnormalities in fetal glucose and insulin secretion and is linked to obesity and diabetes in the offspring, but the mechanisms remain la
Autor:
Sara E. Pinney, Amita Bansal, Apoorva Joshi, Paul Zhiping Wang, David E. Condon, Nicole Robles-Matos
Publikováno v:
J Clin Endocrinol Metab
Context Prenatal exposure to bisphenol A (BPA) is linked to obesity and diabetes but the molecular mechanisms driving these phenomena are not known. Alterations in deoxyribonucleic acid (DNA) methylation in amniocytes exposed to BPA in utero represen
Publikováno v:
Nutrients
Nutrients, Vol 11, Iss 5, p 1191 (2019)
Volume 11
Issue 5
Nutrients, Vol 11, Iss 5, p 1191 (2019)
Volume 11
Issue 5
Early-life iron deficiency results in long-term abnormalities in cognitive function and affective behavior in adulthood. In preclinical models, these effects have been associated with long-term dysregulation of key neuronal genes. While limited evide
Autor:
Yu Chin Lien, Michael K. Georgieff, Phu V. Tran, Kyoung-Jae Won, Jonathan Schug, David E. Condon, Rebecca A. Simmons
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-12 (2018)
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-12 (2018)
Background Identification of differentially methylated regions (DMRs) is the initial step towards the study of DNA methylation-mediated gene regulation. Previous approaches to call DMRs suffer from false prediction, use extreme resources, and/or requ
Autor:
Jianbo Zhao, Frank Noé, Fabian Paul, Douglas H. Turner, Giovanni Bussi, Giovanni Pinamonti, David E. Condon
Nowadays different experimental techniques, such as single molecule or relaxation experiments, can provide dynamic properties of biomolecular systems, but the amount of detail obtainable with these methods is often limited in terms of time or spatial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd73ffe22d11c806f57f3c59d7cacff9
http://hdl.handle.net/20.500.11767/17423
http://hdl.handle.net/20.500.11767/17423
Autor:
Jason D. Tubbs, Melanie Hauser, Douglas H. Turner, Philip C. Bevilacqua, Scott D. Kennedy, David E. Condon
Publikováno v:
Biochemistry
The sequence dependence of RNA energetics is important for predicting RNA structure. Hairpins with C(n) loops are consistently less stable than hairpins with other loops, which suggests the structure of C(n) regions could be unusual in the "unfolded"
Autor:
Brendan C. Mort, Ilyas Yildirim, Ryszard Kierzek, Scott D. Kennedy, Douglas H. Turner, David E. Condon
Publikováno v:
Journal of Chemical Theory and Computation
Molecular dynamics (MD) simulations for RNA tetramers r(AAAA), r(CAAU), r(GACC), and r(UUUU) are benchmarked against 1H–1H NOESY distances and 3J scalar couplings to test effects of RNA torsion parametrizations. Four different starting structures w