Zobrazeno 1 - 10
of 26
pro vyhledávání: '"David E. A. Bush"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 6 (2012)
The lateral nucleus of the amygdala (LA) is a key element in the neural circuit subserving Pavlovian fear conditioning, an animal model of fear and anxiety. Most studies have focused on the role of the LA in fear acquisition and extinction, i.e. how
Externí odkaz:
https://doaj.org/article/fad0f054930844fb9fb9b6e9867aa01a
Autor:
Jo Anna E. Klein, Mian Hou, Robert M. Sears, Joshua P. Johansen, David E. A. Bush, Joseph E. LeDoux, Hillary C. Schiff, Emily K. Smith
Publikováno v:
Neuropsychopharmacology. 42:895-903
Memory formation requires the temporal coordination of molecular events and cellular processes following a learned event. During Pavlovian threat (fear) conditioning (PTC), sensory and neuromodulatory inputs converge on post-synaptic neurons within t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c92a6177b0fe73d8d7f33bec9c26b9
https://doi.org/10.1038/npp.2016.238
https://doi.org/10.1038/npp.2016.238
Publikováno v:
Biological Psychiatry. 73:353-359
Background The lateral nucleus of the amygdala (LA) is a crucial part of the neural circuitry underlying the formation and storage of memories established through fear conditioning. To investigate corticotropin-releasing factor (CRF) contributions to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9da878dcb88b0ebd0921f677d2a71b3e
https://doi.org/10.1016/j.biopsych.2012.08.021
https://doi.org/10.1016/j.biopsych.2012.08.021
Publikováno v:
Depression and Anxiety. 28:186-193
Background: Posttraumatic stress disorder (PTSD) is associated with enhanced noradrenergic activity. Animal and human studies demonstrate that noradrenergic stimulation augments consolidation of fear learning. Retrieval of well-established memories b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7036161c1aa8d11a219816659675e1fd
https://doi.org/10.1002/da.20803
https://doi.org/10.1002/da.20803
Publikováno v:
Biological Psychiatry. 62:1111-1118
Background Selective serotonin reuptake inhibitors (SSRIs) effectively treat various anxiety disorders, although symptoms of anxiety are often exacerbated during early stages of treatment. We previously reported that acute treatment with the SSRI cit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d78bb3bef31771d85aa994874a99ef5
https://doi.org/10.1016/j.biopsych.2006.11.023
https://doi.org/10.1016/j.biopsych.2006.11.023
Publikováno v:
Journal of Traumatic Stress. 20:413-422
Although different people respond differently to threatening events, animal research on the neural basis of fear tends to focus on typical responses. Yet there are substantial individual differences between animals exposed to identical behavioral pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::770eb3cfaf4bea2c273e1e7f4c2e5ed2
https://doi.org/10.1002/jts.20261
https://doi.org/10.1002/jts.20261
Publikováno v:
Neuropsychopharmacology. 32:1929-1940
N-methyl-D-aspartate receptors (NMDARs) contribute to synaptic plasticity underlying learning in a variety of brain systems. Fear extinction, which involves learning to suppress the expression of previously learned fear, appears to require NMDAR acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b7d07f5e46513a90c781793a85edcf
https://doi.org/10.1038/sj.npp.1301316
https://doi.org/10.1038/sj.npp.1301316
Publikováno v:
Learning & Memory. 11:525-535
Fear extinction refers to the ability to adapt as situations change by learning to suppress a previously learned fear. This process involves a gradual reduction in the capacity of a fear-conditioned stimulus to elicit fear by presenting the condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98b6df7727389843fc767b00dcc67ec
https://doi.org/10.1101/lm.79504
https://doi.org/10.1101/lm.79504
Autor:
David E. A. Bush, Luke R. Johnson, Mian Hou, Joseph E. LeDoux, Gregory M. Sullivan, John Apergis
Publikováno v:
Neuroscience. 128:7-14
The bed nucleus of the stria terminalis (BNST) is believed to be a critical relay between the central nucleus of the amygdala (CE) and the paraventricular nucleus of the hypothalamus in the control of hypothalamic-pituitary-adrenal (HPA) responses el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5993d2f2c90aca870ca6b135df5c015
https://doi.org/10.1016/j.neuroscience.2004.06.015
https://doi.org/10.1016/j.neuroscience.2004.06.015
Publikováno v:
Pharmacology & Toxicology. 91:404-413
This article reviews evidence and presents a hypothesis regarding the effects of stress on motivated behaviour, and in particular the observation that stress can have both motivationally inhibitory and motivationally facilitatory effects. This issue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4122b0134a0f6de75881fb1a8559394
https://doi.org/10.1034/j.1600-0773.2002.910620.x
https://doi.org/10.1034/j.1600-0773.2002.910620.x