Zobrazeno 1 - 10
of 87
pro vyhledávání: '"David E. Yocum"'
Autor:
Jeffrey R. Lisse, Donald Gates, David E. Yocum, Timothy G. Lohman, Scott B. Going, Ellen Cussler, Terri Guido, H G. Flint-Wagner
Publikováno v:
JCR: Journal of Clinical Rheumatology. 15:165-171
To assess the effects of a 16-week progressive, individualized, high-intensity strength training program on muscle strength, pain, and function in patients with rheumatoid arthritis (RA).Twenty-four RA patients (men, n = 5; women, n = 19) receiving i
Autor:
Jeffrey R. Lisse, W. David Craig, Lesley Castro, Lisa Hymson, John L Harshbarger, Joseph E Huffstutter, Keith Gilmer, Newman Yeilding, David E. Yocum, Gregory Schimizzi, Shelley Kasle, Peter Callegari, Ronald Hegedus
Publikováno v:
Current Medical Research and Opinion. 23:1967-1979
To examine the impact of an electronic data capture system on patient satisfaction and patient-physician interactions in a rheumatology clinical setting.In this multicenter study, 1079 patients with rheumatoid arthritis completed questionnaires quart
Autor:
Daniel Baker, David E. Yocum, Rene Westhovens, Carrie Wagner, Piet Geusens, Mahboob Rahman, Alberto Berman, J. Han, Ingrid Strusberg
Publikováno v:
Annals of the Rheumatic Diseases. 66:1233-1238
Objective: To determine the efficacy, safety and pharmacokinetics of infliximab dose escalation in patients with rheumatoid arthritis (RA) who had an inadequate response to 3 mg/kg infliximab treatment or whose disease flared after initially respondi
Autor:
Steven A. Mazzuca, Kathleen A. Lane, Leena Sharma, John D. Bradley, Steven T. Hugenberg, Louis W. Heck, Kenneth A. Buckwalter, Chester V. Oddis, Thomas J. Schnitzer, Kenneth D. Brandt, Larry W. Moreland, Frederick Wolfe, David E. Yocum, Barry P. Katz, Susan Manzi
Publikováno v:
Arthritis & Rheumatism. 52:2015-2025
Objective To confirm preclinical data suggesting that doxycycline can slow the progression of osteoarthritis (OA). The primary outcome measure was joint space narrowing (JSN) in the medial tibiofemoral compartment. Methods In this placebo-controlled
Autor:
Steven A. Mazzuca, Chester V. Oddis, Steven T. Hugenberg, John D. Bradley, Kathleen A. Lane, Frederick Wolfe, Kenneth D. Brandt, Barry P. Katz, Susan Manzi, Larry W. Moreland, David E. Yocum, Leena Sharma, Thomas J. Schnitzer, Louis W. Heck
Publikováno v:
Arthritis Care & Research. 51:933-940
Objective To describe the methods by which remarkable levels of subject retention and adherence were achieved in a 30-month multicenter randomized placebo-controlled trial (RCT) of a disease-modifying osteoarthritis drug (DMOAD). Methods Subjects wer
Autor:
John Richard, Xiaolei Tang, Kathryn Nordensson, Douglas F. Lake, David Dejonghe, David E. Yocum
Publikováno v:
Immunology. 112:496-505
Recently, we have described a soluble survival signal for activated lymphocytes from CD14 + cells. As a result of the importance of T lymphocytes in the pathogenesis of rheumatoid arthritis (RA), we speculate a possible role for CD14 + cells in suppo
Autor:
L J Mengle-Gaw, W Wisememandle, F X Burch, Daniel E. Furst, B D Schwartz, David E. Yocum, William G. Bensen, M A Borton, Q A Mekki
Publikováno v:
Rheumatology. 43:992-999
To evaluate the long-term safety of tacrolimus 3 mg/day in patients with rheumatoid arthritis (RA).Patients with active RA who had discontinued all DMARDs for at least 2 weeks and had at least five tender/painful joints and three swollen joints, and
Autor:
Robert G. Lahita, Barri J. Fessler, Michelle Petri, Arthur Kavanaugh, Leonard H. Calabrese, Nancy J. Olsen, Kenneth E. Schwartz, Naomi F. Rothfield, Jacques Caldwell, Jill P. Buyon, Oscar Gluck, Robert T. Spencer, Robert S. Katz, Allan L. Goldman, Kenneth C. Kalunian, E. William St. Clair, Stanley Cohen, David E. Yocum, Kevin G. Moder, Ronald F van Vollenhoven, Philip J. Mease, Betty J. Quarles, Gurwith Marc J, Rita M. Egan, Michael Schiff, Maria Greenwald, Kathryn Hobbs, Vibeke Strand, Rosalind Ramsey-Goldman, Richard P. Polisson, Susan Manzi, Ellen M. Ginzler, Mark C. Genovese, Joan T. Merrill, Larry W. Moreland, Mark J. Iannini
Publikováno v:
Arthritis & Rheumatism. 50:2858-2868
Objective To determine whether prasterone administration results in improvement or stabilization of systemic lupus erythematosus (SLE) disease activity and its symptoms. Methods Women with active SLE were treated with prasterone 200 mg/day plus stand
Autor:
Jeffrey L. Kaine, Mary Ann Borton, Jon T Stevenson, Daniel E. Furst, Benjamin D Schwartz, Wayne Wisemandle, David E. Yocum, Laurel J Mengle-Gaw, Andrew R. Baldassare, Qais A Mekki
Publikováno v:
Arthritis & Rheumatism. 48:3328-3337
Objective To evaluate the efficacy and safety of tacrolimus as monotherapy in controlling the signs and symptoms of patients with rheumatoid arthritis (RA). Methods This was a 6-month, phase III, double-blind, multicenter study. Patients with active
Publikováno v:
Immunology. 107:56-68
T-cell activation requires at least two signals: antigen and a costimulatory signal. As antigen-presenting cells play an important role in this area, the role of CD14+ cells in T-cell activation, proliferation and activation-induced cell death (AICD)