Zobrazeno 1 - 10
of 44
pro vyhledávání: '"David E Symer"'
Autor:
Alix Warburton, Catherine J Redmond, Katharine E Dooley, Haiqing Fu, Maura L Gillison, Keiko Akagi, David E Symer, Mirit I Aladjem, Alison A McBride
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007179 (2018)
Integration of human papillomavirus (HPV) genomes into cellular chromatin is common in HPV-associated cancers. Integration is random, and each site is unique depending on how and where the virus integrates. We recently showed that tandemly integrated
Externí odkaz:
https://doaj.org/article/2c5f67a370b1458995c9eda5e1cf579d
Autor:
Huiling He, Wei Li, Dayong Wu, Rebecca Nagy, Sandya Liyanarachchi, Keiko Akagi, Jaroslaw Jendrzejewski, Hong Jiao, Kevin Hoag, Bernard Wen, Mukund Srinivas, Gavisha Waidyaratne, Rui Wang, Anna Wojcicka, Ilene R Lattimer, Elzbieta Stachlewska, Malgorzata Czetwertynska, Joanna Dlugosinska, Wojciech Gierlikowski, Rafal Ploski, Marek Krawczyk, Krystian Jazdzewski, Juha Kere, David E Symer, Victor Jin, Qianben Wang, Albert de la Chapelle
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e61920 (2013)
Thyroid cancer shows high heritability but causative genes remain largely unknown. According to a common hypothesis the genetic predisposition to thyroid cancer is highly heterogeneous; being in part due to many different rare alleles. Here we used l
Externí odkaz:
https://doaj.org/article/651e24fe49534fd19638923f21c5f333
Autor:
Erin Hertlein, Kyle A Beckwith, Gerard Lozanski, Timothy L Chen, William H Towns, Amy J Johnson, Amy Lehman, Amy S Ruppert, Brad Bolon, Leslie Andritsos, Arletta Lozanski, Laura Rassenti, Weiqiang Zhao, Tiina M Jarvinen, Leigha Senter, Carlo M Croce, David E Symer, Albert de la Chapelle, Nyla A Heerema, John C Byrd
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76607 (2013)
Studies of chronic lymphocytic leukemia (CLL) have yielded substantial progress, however a lack of immortalized cell lines representative of the primary disease has hampered a full understanding of disease pathogenesis and development of new treatmen
Externí odkaz:
https://doaj.org/article/6701b5761778490aa7e468949244dd8d
Autor:
Sonia M. Setayesh, Libere J. Ndacayisaba, Kate E. Rappard, Valerie Hennes, Luz Yurany Moreno Rueda, Guilin Tang, Pei Lin, Robert Z. Orlowski, David E. Symer, Elisabet E. Manasanch, Stephanie N. Shishido, Peter Kuhn
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-10 (2023)
Abstract Multiple myeloma (MM) is accompanied by alterations to the normal plasma cell (PC) proteome, leading to changes to the tumor microenvironment and disease progression. There is a great need for understanding the consequences that lead to MM p
Externí odkaz:
https://doaj.org/article/a0b8d1a07e1b4a459e80c405e29213aa
Autor:
Keiko Akagi, David E. Symer, Medhat Mahmoud, Bo Jiang, Sara Goodwin, Darawalee Wangsa, Zhengke Li, Weihong Xiao, Joe Dan Dunn, Thomas Ried, Kevin R. Coombes, Fritz J. Sedlazeck, Maura L. Gillison
Publikováno v:
Cancer Discovery. 13:910-927
The human papillomavirus (HPV) genome is integrated into host DNA in most HPV-positive cancers, but the consequences for chromosomal integrity are unknown. Continuous long-read sequencing of oropharyngeal cancers and cancer cell lines identified a pr
Autor:
Maura L. Gillison, Fritz J. Sedlazeck, Kevin R. Coombes, Thomas Ried, Joe Dan Dunn, Weihong Xiao, Zhengke Li, Darawalee Wangsa, Sara Goodwin, Bo Jiang, Medhat Mahmoud, David E. Symer, Keiko Akagi
The human papillomavirus (HPV) genome is integrated into host DNA in most HPV-positive cancers, but the consequences for chromosomal integrity are unknown. Continuous long-read sequencing of oropharyngeal cancers and cancer cell lines identified a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdefae27ab96f07bb07c9bbf25f0e7f
https://doi.org/10.1158/2159-8290.c.6534676.v3
https://doi.org/10.1158/2159-8290.c.6534676.v3
Autor:
Manoj Kannan, Jingfeng Li, Sarah E. Fritz, Kathryn E. Husarek, Jonathan C. Sanford, Teresa L. Sullivan, Pawan Kumar Tiwary, Wenfeng An, Jef D. Boeke, David E. Symer
Publikováno v:
Mobile DNA, Vol 8, Iss 1, Pp 1-19 (2017)
Abstract Background The ongoing mobilization of mammalian transposable elements (TEs) contributes to natural genetic variation. To survey the epigenetic control and expression of reporter genes inserted by L1 retrotransposition in diverse cellular an
Externí odkaz:
https://doaj.org/article/dd69d43bc0c047fbb3b89686c598e427
Autor:
Minghao Dang, Li Qin, Wei Tan, Liping Dong, Hans C. Lee, Krina Patel, Luz Yurany Moreno Rueda, Pei Lin, Hima Bansal, David Berrios, Sheeba K Thomas, Donna M. Weber, David E. Symer, Linghua Wang, Elisabet E. Manasanch, Robert Z. Orlowski
Publikováno v:
Blood. 140:7122-7124
Autor:
Maura L. Gillison, Fritz J. Sedlazeck, Kevin R. Coombes, Thomas Ried, Joe Dan Dunn, Weihong Xiao, Zhengke Li, Darawalee Wangsa, Sara Goodwin, Bo Jiang, Medhat Mahmoud, David E. Symer, Keiko Akagi
Figure S1.1. Circos plots of human genomes. Figure S1.2. Circos plots of HPV genomes. Figure S1.3. PacBio HiFi read length distributions. Figure S1.4. Oxford Nanopore (ONT) read length distributions. Figure S2.1. Detection of circularized mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268283e949af29b02688e33f29c20f97
https://doi.org/10.1158/2159-8290.22546957.v1
https://doi.org/10.1158/2159-8290.22546957.v1
Autor:
Maura L. Gillison, David E. Symer, Anna L. Trivett, William H. Westra, Weihong Xiao, Wayne M. Koch, Yuri Agrawal
Purpose: Oral human papillomavirus (HPV) infection is a risk factor for head and neck squamous cell carcinoma (HNSCC), and is a concern for patients with HPV-positive HNSCC and their partners. The prevalence of oral HPV infection before and after can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ded7c95f94aee904a30eab41b38adde
https://doi.org/10.1158/1078-0432.c.6517192.v1
https://doi.org/10.1158/1078-0432.c.6517192.v1