Zobrazeno 1 - 10
of 97
pro vyhledávání: '"David E Ott"'
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0195246 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0023703.].
Externí odkaz:
https://doaj.org/article/ec85ebf849f645bf9d7781d3f78c1f65
Autor:
Christine M Fennessey, Mykola Pinkevych, Taina T Immonen, Arnold Reynaldi, Vanessa Venturi, Priyanka Nadella, Carolyn Reid, Laura Newman, Leslie Lipkey, Kelli Oswald, William J Bosche, Matthew T Trivett, Claes Ohlen, David E Ott, Jacob D Estes, Gregory Q Del Prete, Jeffrey D Lifson, Miles P Davenport, Brandon F Keele
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006359 (2017)
HIV and SIV infection dynamics are commonly investigated by measuring plasma viral loads. However, this total viral load value represents the sum of many individual infection events, which are difficult to independently track using conventional seque
Externí odkaz:
https://doaj.org/article/12624c7f2b5640c181fb68da867a31e1
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23703 (2011)
The SIV/rhesus macaque model for HIV/AIDS is a powerful system for examining the contribution of T cells in the control of AIDS viruses. To better our understanding of CD8(+) T-cell control of SIV replication in CD4(+) T cells, we asked whether TCRs
Externí odkaz:
https://doaj.org/article/4a1cc3fc6c7d41ebb2e59eaaa0004694
Autor:
Karine Gousset, Sherimay D Ablan, Lori V Coren, Akira Ono, Ferri Soheilian, Kunio Nagashima, David E Ott, Eric O Freed
Publikováno v:
PLoS Pathogens, Vol 4, Iss 3, p e1000015 (2008)
HIV-1 particle production is driven by the Gag precursor protein Pr55(Gag). Despite significant progress in defining both the viral and cellular determinants of HIV-1 assembly and release, the trafficking pathway used by Gag to reach its site of asse
Externí odkaz:
https://doaj.org/article/510bb4203f7841c1ac00215eae83cfd5
Publikováno v:
BioTechniques, Vol 58, Iss 3, Pp 135-139 (2015)
Here we present an improved strategy for producing T-cell receptor (TCR)-expressing retroviral vectors using a Golden Gate cloning strategy. This method takes advantage of the modular nature of TCR genes by directly amplifying TCR α and β variable
Externí odkaz:
https://doaj.org/article/bc0005e9fbe34f0d842482bead6daed8
Autor:
Daniel H. Appella, Hans F. Luecke, Lisa M. Miller Jenkins, John M. Louis, David E. Ott, Elliott L. Paine, Kara M. George Rosenker, Robert J. Gorelick, Lalit Deshmukh, Herman Nikolayevskiy, Elena Chertova, Gaelyn C. Lyons, G. Marius Clore, Michael T. Scerba
Publikováno v:
J Am Chem Soc
For HIV to become infectious, any new virion produced from an infected cell must undergo a maturation process that involves the assembly of viral polyproteins Gag and Gag–Pol at the membrane surface. The self-assembly of these viral proteins drives
Autor:
Lori V. Coren, Sumiti Jain, David E. Ott, Matthew W. Breed, Gregory Q. Del Prete, Matthew T. Trivett, Adrienne E. Swanstrom, Eugene V. Barsov, Jeffrey D. Lifson, Claire Deleage, Brenna J. Hill, Joshua A. Kramer, James D. Burke
Publikováno v:
Journal of Virology. 93
Adoptive cell transfer (ACT) is a powerful experimental approach to directly study T-cell-mediated immunity in vivo. In the rhesus macaque AIDS virus model, infusing simian immunodeficiency virus (SIV)-infected animals with CD8 T cells engineered to
Autor:
Matthew T, Trivett, James D, Burke, Claire, Deleage, Lori V, Coren, Brenna J, Hill, Sumiti, Jain, Eugene V, Barsov, Matthew W, Breed, Joshua A, Kramer, Gregory Q, Del Prete, Jeffrey D, Lifson, Adrienne E, Swanstrom, David E, Ott
Publikováno v:
Journal of virology. 93(21)
Adoptive cell transfer (ACT) is a powerful experimental approach to directly study T-cell-mediated immunity in vivo. In the rhesus macaque AIDS virus model, infusing simian immunodeficiency virus (SIV)-infected animals with CD8 T cells engineered to
A PLPPV sequence in the p8 region of Gag provides late domain function for mouse mammary tumor virus
Publikováno v:
Virology
The late (L) domain sequence used by mouse mammary tumor virus (MMTV) remains undefined. Similar to other L domain-containing proteins, MMTV p8 and p14 NC proteins are monoubiquitinated, suggesting L domain function. Site-directed mutagenesis of p8,
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0195246 (2018)
PLoS ONE, Vol 13, Iss 3, p e0195246 (2018)
The SIV/rhesus macaque model for HIV/AIDS is a powerful system for examining the contribution of T cells in the control of AIDS viruses. To better our understanding of CD8(+) T-cell control of SIV replication in CD4(+) T cells, we asked whether TCRs