Zobrazeno 1 - 10
of 26
pro vyhledávání: '"David E J Waddington"'
Autor:
Sheng Shen, Neha Koonjoo, Thomas Boele, Jiaqi Lu, David E. J. Waddington, Marie Zhang, Matthew S. Rosen
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Superparamagnetic iron oxide nanoparticles (SPIONs) are characterized by their exceptional susceptibility and relaxivity at ultra-low field (ULF) regimes, make them a promising contrast agent (CA) for ULF MRI. Despite their distinct advantag
Externí odkaz:
https://doaj.org/article/7294161dd5ae47b190c2f094b9599dbd
Autor:
James Grover, Paul Liu, Bin Dong, Shanshan Shan, Brendan Whelan, Paul Keall, David E. J. Waddington
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-12 (2024)
Abstract Background Magnetic resonance imaging (MRI) offers superb non-invasive, soft tissue imaging of the human body. However, extensive data sampling requirements severely restrict the spatiotemporal resolution achievable with MRI. This limits the
Externí odkaz:
https://doaj.org/article/3ae5da85b637451d8ce8e9afefe31e93
Autor:
Caterina Brighi, David E. J. Waddington, Paul J. Keall, Jeremy Booth, Kieran O’Brien, Shona Silvester, Jonathon Parkinson, Marco Mueller, Jackie Yim, Dale L. Bailey, Michael Back, James Drummond
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundGlioblastoma (GBM) is the most aggressive type of brain cancer, with a 5-year survival rate of ~5% and most tumours recurring locally within months of first-line treatment. Hypoxia is associated with worse clinical outcomes in GBM, as it le
Externí odkaz:
https://doaj.org/article/5edcdad8f4af4d379976474a7c4ef04a
Autor:
Caterina Brighi, Simon Puttick, Amanda Woods, Paul Keall, Paul A. Tooney, David E. J. Waddington, Vicki Sproule, Stephen Rose, Michael Fay
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16208 (2023)
The aim of this prospective clinical study was to evaluate the potential of the prostate specific membrane antigen (PSMA) targeting ligand, [68Ga]-PSMA–Glu–NH–CO–NH–Lys-2-naphthyl-L-Ala-cyclohexane-DOTA ([68Ga]Ga-PSMA-617) as a positron emi
Externí odkaz:
https://doaj.org/article/2591de13571e43b8b787a17e369f0162
Autor:
David E. J. Waddington, Mathieu Sarracanie, Huiliang Zhang, Najat Salameh, David R. Glenn, Ewa Rej, Torsten Gaebel, Thomas Boele, Ronald L. Walsworth, David J. Reilly, Matthew S. Rosen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Hyperpolarized magnetic resonance imaging can enhance imaging contrast by orders of magnitude, but applications are limited by the thermal relaxation of hyperpolarized states. Here, Waddingtonet al. demonstrate the on-demand hyperpolarization of hydr
Externí odkaz:
https://doaj.org/article/b51b984e0c19410db97859d79257ccb7
Autor:
Shanshan Shan, Yang Gao, Paul Z. Y. Liu, Brendan Whelan, Hongfu Sun, Bin Dong, Feng Liu, David E. J. Waddington
Publikováno v:
Magnetic Resonance in Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eea5b1d70024c52449544e7062c2cfc
https://doi.org/10.1002/mrm.29684
https://doi.org/10.1002/mrm.29684
Autor:
Rosie J. Goodburn, Marielle E. P. Philippens, Thierry L. Lefebvre, Aly Khalifa, Tom Bruijnen, Joshua N. Freedman, David E. J. Waddington, Eyesha Younus, Eric Aliotta, Gabriele Meliadò, Teo Stanescu, Wajiha Bano, Ali Fatemi‐Ardekani, Andreas Wetscherek, Uwe Oelfke, Nico van den Berg, Ralph P. Mason, Petra J. van Houdt, James M. Balter, Oliver J. Gurney‐Champion
Publikováno v:
Magnetic resonance in medicine, 88(6), 2592-2608. John Wiley and Sons Inc.
Radiation therapy is a major component of cancer treatment pathways worldwide. The main aim of this treatment is to achieve tumor control through the delivery of ionizing radiation while preserving healthy tissues for minimal radiation toxicity. Beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0d6820d3c90e026afff3706ae29203
https://pure.amc.nl/en/publications/the-future-of-mri-in-radiation-therapy(37c766b5-8987-4487-aee4-96a8a4a383b4).html
https://pure.amc.nl/en/publications/the-future-of-mri-in-radiation-therapy(37c766b5-8987-4487-aee4-96a8a4a383b4).html
Autor:
Paul J. Keall, Caterina Brighi, Carri Glide-Hurst, Gary Liney, Paul Z. Y. Liu, Suzanne Lydiard, Chiara Paganelli, Trang Pham, Shanshan Shan, Alison C. Tree, Uulke A. van der Heide, David E. J. Waddington, Brendan Whelan
Publikováno v:
Nature Reviews Clinical Oncology, 19(7), 458-470. NATURE PORTFOLIO
MRI can help to categorize tissues as malignant or non-malignant both anatomically and functionally, with a high level of spatial and temporal resolution. This non-invasive imaging modality has been integrated with radiotherapy in devices that can di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e5ff44d7bce82a837ea109f9e6e04c
https://doi.org/10.1038/s41571-022-00631-3
https://doi.org/10.1038/s41571-022-00631-3
Autor:
Caterina Brighi, Paul J Keall, Lois C Holloway, Amy Walker, Brendan Whelan, Philip C de Witt Hamer, Niels Verburg, Farhannah Aly, Cathy Chen, Eng-Siew Koh, David E J Waddington
Publikováno v:
Neuro-oncology advances, 4(1):vdac134. Oxford University Press
Brighi, C, Keall, P J, Holloway, L C, Walker, A, Whelan, B, de Witt Hamer, P C, Verburg, N, Aly, F, Chen, C, Koh, E-S & Waddington, D E J 2022, ' An investigation of the conformity, feasibility, and expected clinical benefits of multiparametric MRI-guided dose painting radiotherapy in glioblastoma ', Neuro-oncology advances, vol. 4, no. 1, vdac134 . https://doi.org/10.1093/noajnl/vdac134
Brighi, C, Keall, P J, Holloway, L C, Walker, A, Whelan, B, de Witt Hamer, P C, Verburg, N, Aly, F, Chen, C, Koh, E-S & Waddington, D E J 2022, ' An investigation of the conformity, feasibility, and expected clinical benefits of multiparametric MRI-guided dose painting radiotherapy in glioblastoma ', Neuro-oncology advances, vol. 4, no. 1, vdac134 . https://doi.org/10.1093/noajnl/vdac134
Background New technologies developed to improve survival outcomes for glioblastoma (GBM) continue to have limited success. Recently, image-guided dose painting (DP) radiotherapy has emerged as a promising strategy to increase local control rates. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc70d4b393decaed081af6703e8b836e
https://doi.org/10.1093/noajnl/vdac134
https://doi.org/10.1093/noajnl/vdac134
Autor:
David E J, Waddington, Mathieu, Sarracanie, Najat, Salameh, Fanny, Herisson, Cenk, Ayata, Matthew S, Rosen
Publikováno v:
NMR in biomedicine. 31(5)
Overhauser-enhanced MRI (OMRI) is an electron-proton double-resonance imaging technique of interest for its ability to non-invasively measure the concentration and distribution of free radicals. In vivo OMRI experiments are typically undertaken at ul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b8f64c9c4bfe8f0fd477e2e3e294570
https://pubmed.ncbi.nlm.nih.gov/29493032
https://pubmed.ncbi.nlm.nih.gov/29493032