Zobrazeno 1 - 10
of 251
pro vyhledávání: '"David E Griffith"'
Publikováno v:
Southwest Respiratory and Critical Care Chronicles, Vol 2, Iss 8, Pp 5-16 (2014)
We recently identified four patients with pulmonary embolism (PE) who presented with progressive, but nonspecific, respiratory symptoms and were initially diagnosed with an exacerbation of established or presumed airflow obstruction. No specific expl
Externí odkaz:
https://doaj.org/article/62f599c6faa841d78758ea4571a67901
Autor:
Jiwon Lyu, Drew E. Narum, Susan L. Baldwin, Sasha E. Larsen, Xiyuan Bai, David E. Griffith, Véronique Dartois, Threnesan Naidoo, Adrie J. C. Steyn, Rhea N. Coler, Edward D. Chan
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Granulomas, organized aggregates of immune cells which form in response to Mycobacterium tuberculosis (Mtb), are characteristic but not exclusive of tuberculosis (TB). Despite existing investigations on TB granulomas, the determinants that differenti
Externí odkaz:
https://doaj.org/article/f38a0bf0022744709534be1b190a69be
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 8, Pp 1907-1920 (2024)
Abstract Introduction The incidence and prevalence of nontuberculous mycobacterial pulmonary disease (NTM-PD) are increasing globally. Approximately 80% of NTM-PD cases in Japan and five countries within Europe (Eur5; France, Germany, Italy, Spain, a
Externí odkaz:
https://doaj.org/article/2da9206acc65482789e2d816bf081c48
Autor:
Xiyuan Bai, Junfeng Gao, Xiaoyu Guan, Drew E. Narum, Lorelenn B. Fornis, David E. Griffith, Bifeng Gao, Robert A. Sandhaus, Hua Huang, Edward D. Chan
Publikováno v:
Physiological Reports, Vol 12, Iss 14, Pp n/a-n/a (2024)
Abstract Alpha‐1‐antitrypsin (AAT) plays a homeostatic role in attenuating excessive inflammation and augmenting host defense against microbes. We demonstrated previously that AAT binds to the glucocorticoid receptor (GR) resulting in significant
Externí odkaz:
https://doaj.org/article/cd36fff562424506b50b4589d90ee722
Autor:
Andrew B. Wolf, Kelli M. Money, Arun Chandnani, Charles L. Daley, David E. Griffith, Lakshmi Chauhan, Nathan Coffman, Amanda L. Piquet, Kenneth L. Tyler, Shanta M. Zimmer, Brian T. Montague, Sarah Mann, Daniel M. Pastula
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 8, Pp 1655-1658 (2023)
Mycobacterium abscessus infections have been reported as adverse events related to medical tourism. We report M. abscessus meningitis in a patient who traveled from Colorado, USA, to Mexico to receive intrathecal stem cell injections as treatment for
Externí odkaz:
https://doaj.org/article/b15fdced5e354e61aaa1c836cafb04d7
Autor:
Xiyuan Bai, Deepshikha Verma, Cindy Garcia, Ariel Musheyev, Kevin Kim, Lorelenn Fornis, David E. Griffith, Li Li, Nicholas Whittel, Jacob Gadwa, Tamara Ohanjanyan, Matthew J. Eggleston, Manuel Galvan, Brian M. Freed, Diane Ordway, Edward D. Chan
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionA strong epidemiologic link exists between cigarette smoke (CS) exposure and susceptibility to tuberculosis (TB). Macrophage and murine studies showed that CS and nicotine impair host-protective immune cells against Mycobacterium tubercul
Externí odkaz:
https://doaj.org/article/26d83c75c82943268a6d72ddd2c09bd9
Publikováno v:
European Respiratory Review, Vol 31, Iss 163 (2022)
Nontuberculous mycobacterial pulmonary disease (NTM-PD) remains a challenging condition to diagnose and treat effectively. Treatment of NTM-PD is prolonged, frequently associated with adverse effects and has variable success. In this review, we consi
Externí odkaz:
https://doaj.org/article/122af0c2ad194141bd3fe14bc292097a
Autor:
Xiyuan Bai, An Bai, Michele Tomasicchio, James R. Hagman, Ashley M. Buckle, Arnav Gupta, Vineela Kadiyala, Shaun Bevers, Karina A. Serban, Kevin Kim, Zhihong Feng, Kathrin Spendier, Guy Hagen, Lorelenn Fornis, David E. Griffith, Monika Dzieciatkowska, Robert A. Sandhaus, Anthony N. Gerber, Edward D. Chan
Publikováno v:
The Journal of Immunology. 209:1746-1759
α1-Antitrypsin (AAT), a serine protease inhibitor, is the third most abundant protein in plasma. Although the best-known function of AAT is irreversible inhibition of elastase, AAT is an acute-phase reactant and is increasingly recognized to have a
Autor:
Timothy R. Aksamit, Richard J. Wallace, Dayton W. Yuen, Kozo Morimoto, Wouter Hoefsloot, David E. Griffith, Doreen Addrizzo-Harris, Kevin L. Winthrop, Kevin C. Mange, Monika Ciesielska, Rachel Thomson, Jakko van Ingen, Chris Coulter, Stephen K. Field, Patrick A. Flume, Barbara A. Brown-Elliott
Publikováno v:
Chest. 160:831-842
Background: In the CONVERT study, treatment with amikacin liposome inhalation suspension (ALIS) added to guideline-based therapy (GBT) met the primary end point of increased culture conversion by month 6 in patients with treatment-refractory Mycobact
Autor:
Timothy R. Aksamit, David E. Griffith
Publikováno v:
Chest. 159:1372-1381
Management of Mycobacterium avium complex (MAC) lung disease is complicated, frequently unsuccessful, and frustrating to patients and clinicians. The initial treatment effort may not be directed solely at MAC infection, rather it is often initiating