Výsledky vyhledávání - "David E Green"

Akademický článek

PPARγ Ligands Attenuate Hypoxia-Induced Proliferation in Human Pulmonary Artery Smooth Muscle Cells through Modulation of MicroRNA-21.

Autor: David E Green, Tamara C Murphy, Bum-Yong Kang, Charles D Searles, C Michael Hart

Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0133391 (2015)

Pulmonary hypertension (PH) is a progressive and often fatal disorder whose pathogenesis involves pulmonary artery smooth muscle cell (PASMC) proliferation. Although modern PH therapies have significantly improved survival, continued progress rests o

Externí odkaz: https://doaj.org/article/86c98e132dec4a52a4f13ca995b6d5c6

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Akademický článek

Hypoxia mediates mutual repression between microRNA-27a and PPARγ in the pulmonary vasculature.

Autor: Bum-Yong Kang, Kathy K Park, David E Green, Kaiser M Bijli, Charles D Searles, Roy L Sutliff, C Michael Hart

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e79503 (2013)

Pulmonary hypertension (PH) is a serious disorder that causes significant morbidity and mortality. The pathogenesis of PH involves complex derangements in multiple pathways including reductions in peroxisome proliferator-activated receptor gamma (PPA

Externí odkaz: https://doaj.org/article/78c7a7bd51d44a6e8558eaebd10efbd1

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