Zobrazeno 1 - 10
of 637
pro vyhledávání: '"David E Fisher"'
Autor:
Mariah M Johnson, Sancy A Leachman, Lisa G Aspinwall, Lee D Cranmer, Clara Curiel-Lewandrowski, Vernon K Sondak, Clara E Stemwedel, Susan M Swetter, John Vetto, Tawnya Bowles, Robert P Dellavalle, Larisa J Geskin, Douglas Grossman, Kenneth F Grossmann, Jason E Hawkes, Joanne M Jeter, Caroline C Kim, John M Kirkwood, Aaron R Mangold, Frank Meyskens, Michael E Ming, Kelly C Nelson, Michael Piepkorn, Brian P Pollack, June K Robinson, Arthur J Sober, Shannon Trotter, Suraj S Venna, Sanjiv Agarwala, Rhoda Alani, Bruce Averbook, Anna Bar, Mirna Becevic, Neil Box, William E Carson, Pamela B Cassidy, Suephy C Chen, Emily Y Chu, Darrel L Ellis, Laura K Ferris, David E Fisher, Kari Kendra, David H Lawson, Philip D Leming, Kim A Margolin, Svetomir Markovic, Mary C Martini, Debbie Miller, Debjani Sahni, William H Sharfman, Jennifer Stein, Alexander J Stratigos, Ahmad Tarhini, Matthew H Taylor, Oliver J Wisco, Michael K Wong
Publikováno v:
Melanoma Management, Vol 4, Iss 1, Pp 13-37 (2017)
Melanoma is usually apparent on the skin and readily detected by trained medical providers using a routine total body skin examination, yet this malignancy is responsible for the majority of skin cancer-related deaths. Currently, there is no national
Externí odkaz:
https://doaj.org/article/8e14d4bd2ae34bdfbf467c03771d28b3
Autor:
Elisabeth Roider, Alexandra I. T. Lakatos, Alicia M. McConnell, Poguang Wang, Alina Mueller, Akinori Kawakami, Jennifer Tsoi, Botond L. Szabolcs, Anna A. Ascsillán, Yusuke Suita, Vivien Igras, Jennifer A. Lo, Jennifer J. Hsiao, Rebecca Lapides, Dorottya M. P. Pál, Anna S. Lengyel, Alexander Navarini, Arimichi Okazaki, Othon Iliopoulos, István Németh, Thomas G. Graeber, Leonard Zon, Roger W. Giese, Lajos V. Kemeny, David E. Fisher
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Microphthalmia-associated transcription factor (MITF) is a master regulator of melanocyte function, development and plays a significant role in melanoma pathogenesis. MITF genomic amplification promotes melanoma development, and it can facil
Externí odkaz:
https://doaj.org/article/cc94d2d3111647cfb25391c16c6a03e3
Autor:
Mack Y Su, David E Fisher
Publikováno v:
PLoS Medicine, Vol 13, Iss 12, p e1002196 (2016)
In a Perspective, Mack Su and David Fisher discuss the development of immunotherapies for treatment of melanoma and other cancer types.
Externí odkaz:
https://doaj.org/article/6b1cd19c2f8f45a2844e0278d6860040
Autor:
Kanika Kamal, David Xiang, Katherine Young, David E. Fisher, Arash Mostaghimi, Nicholas Theodosakis
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 8, Pp 2109-2117 (2024)
Abstract Introduction Limited epidemiologic data has suggested direct associations between hair pigment, race, and incidence of alopecia areata (AA). Here, we examine the relationship between natural hair color, race, and the lifetime risk alopecia.
Externí odkaz:
https://doaj.org/article/711eef10c46e41d6953e3cb2caf67320
Autor:
Yun Xia, Ying Li, Kenneth D Westover, Jiaming Sun, Hongxiang Chen, Jianming Zhang, David E Fisher
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155217 (2016)
α-Mangostin is a natural product commonly used in Asia for cosmetic and medicinal applications including topical treatment of acne and skin cancer. Towards finding new pharmacological strategies that overcome NRAS mutant melanoma, we performed a cel
Externí odkaz:
https://doaj.org/article/16c7d1a8643e4dc5b9d885310aafc6af
Autor:
Adam A Friedman, Arnaud Amzallag, Iulian Pruteanu-Malinici, Subash Baniya, Zachary A Cooper, Adriano Piris, Leeza Hargreaves, Vivien Igras, Dennie T Frederick, Donald P Lawrence, Daniel A Haber, Keith T Flaherty, Jennifer A Wargo, Sridhar Ramaswamy, Cyril H Benes, David E Fisher
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140310 (2015)
A newer generation of anti-cancer drugs targeting underlying somatic genetic driver events have resulted in high single-agent or single-pathway response rates in selected patients, but few patients achieve complete responses and a sizeable fraction o
Externí odkaz:
https://doaj.org/article/2c65cc61a9ae4bf8a9a2e40f9c38d289
Autor:
Dennie T Frederick, Roberto A Salas Fragomeni, Aislyn Schalck, Isabel Ferreiro-Neira, Taylor Hoff, Zachary A Cooper, Rizwan Haq, David J Panka, Lawrence N Kwong, Michael A Davies, James C Cusack, Keith T Flaherty, David E Fisher, James W Mier, Jennifer A Wargo, Ryan J Sullivan
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101286 (2014)
While response rates to BRAF inhibitiors (BRAFi) are high, disease progression emerges quickly. One strategy to delay the onset of resistance is to target anti-apoptotic proteins such as BCL-2, known to be associated with a poor prognosis. We analyze
Externí odkaz:
https://doaj.org/article/8814805ec5d04e5395a5f296e5e3124d
Autor:
Matija Dreze, Anne S Calkins, Judit Gálicza, Daniel J Echelman, Mathew R Schnorenberg, Gillian L Fell, Shigenori Iwai, David E Fisher, David Szüts, J Dirk Iglehart, Jean-Bernard Lazaro
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85896 (2014)
Because cells are constantly subjected to DNA damaging insults, DNA repair pathways are critical for genome integrity [1]. DNA damage recognition protein complexes (DRCs) recognize DNA damage and initiate DNA repair. The DNA-Damage Binding protein 2
Externí odkaz:
https://doaj.org/article/75b1ffd2a6a74e609d2a41653e46bd91
Autor:
Juying Li, Jun S Song, Robert J A Bell, Thanh-Nga T Tran, Rizwan Haq, Huifei Liu, Kevin T Love, Robert Langer, Daniel G Anderson, Lionel Larue, David E Fisher
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002688 (2012)
Studies of coat color mutants have greatly contributed to the discovery of genes that regulate melanocyte development and function. Here, we generated Yy1 conditional knockout mice in the melanocyte-lineage and observed profound melanocyte deficiency
Externí odkaz:
https://doaj.org/article/c260fac85a7143449238c14fcb8aa29a
Autor:
Maja M Janas, Mehdi Khaled, Steffen Schubert, Jacob G Bernstein, David Golan, Rosa A Veguilla, David E Fisher, Noam Shomron, Carmit Levy, Carl D Novina
Publikováno v:
PLoS Genetics, Vol 7, Iss 10, p e1002330 (2011)
The majority of mammalian microRNA (miRNA) genes reside within introns of protein-encoding and non-coding genes, yet the mechanisms coordinating primary transcript processing into both mature miRNA and spliced mRNA are poorly understood. Analysis of
Externí odkaz:
https://doaj.org/article/4f3eba0b377444649e173cfb613834ef