Zobrazeno 1 - 10
of 39
pro vyhledávání: '"David E Cook"'
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011525 (2023)
Through the association of protein complexes to DNA, the eukaryotic nuclear genome is broadly organized into open euchromatin that is accessible for enzymes acting on DNA and condensed heterochromatin that is inaccessible. Chemical and physical alter
Externí odkaz:
https://doaj.org/article/4e7e75b414564b9d9443333c72041e0f
Publikováno v:
PLoS Genetics, Vol 17, Iss 2, p e1009376 (2021)
Transcriptional dynamic in response to environmental and developmental cues are fundamental to biology, yet many mechanistic aspects are poorly understood. One such example is fungal plant pathogens, which use secreted proteins and small molecules, t
Externí odkaz:
https://doaj.org/article/436f1eacb3b64531b33a7c80257d23e3
Publikováno v:
eLife, Vol 9 (2020)
Genomes store information at scales beyond the linear nucleotide sequence, which impacts genome function at the level of an individual, while influences on populations and long-term genome function remains unclear. Here, we addressed how physical and
Externí odkaz:
https://doaj.org/article/ba24bc4cb3e34b60bbdb76846a0513d0
Autor:
Wei Zhang, Jason A Corwin, Daniel Harrison Copeland, Julie Feusier, Robert Eshbaugh, David E Cook, Suzi Atwell, Daniel J Kliebenstein
Publikováno v:
eLife, Vol 8 (2019)
A central goal of studying host-pathogen interaction is to understand how host and pathogen manipulate each other to promote their own fitness in a pathosystem. Co-transcriptomic approaches can simultaneously analyze dual transcriptomes during infect
Externí odkaz:
https://doaj.org/article/a3d98676b685499a8e066dd60743c790
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1005920 (2016)
Externí odkaz:
https://doaj.org/article/8ed4a83411274703bf0acd8c2c6a48a7
Autor:
David E. Torres, H. Martin Kramer, Vittorio Tracanna, Gabriel L. Fiorin, David E. Cook, Michael F. Seidl, Bart P.H.J. Thomma
The spatial organization of eukaryotic genomes is linked to their biological functions, although it is not clear how this impacts the overall evolution of a genome. Here, we uncover the three-dimensional (3D) genome organization of the phytopathogenV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dcb8a4fc3c607c2154af913987c677e
https://doi.org/10.1101/2023.04.04.535574
https://doi.org/10.1101/2023.04.04.535574
Autor:
Jun Huang, David Rowe, Pratima Subedi, Wei Zhang, Tyler Suelter, Barbara Valent, David E. Cook
Publikováno v:
Nature Communications. 13
CRISPR-Cas mediated genome engineering has revolutionized functional genomics. However, understanding of DNA repair following Cas-mediated DNA cleavage remains incomplete. Using Cas12a ribonucleoprotein genome editing in the fungal pathogen, Magnapor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70439af96d5259822969339101c93977
https://doi.org/10.1038/s41467-022-34736-1
https://doi.org/10.1038/s41467-022-34736-1
Publikováno v:
Physiological and Molecular Plant Pathology. 125:102006
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6fc93155dc881434ac916aac0ce0b9c
https://doi.org/10.1016/j.pmpp.2023.102006
https://doi.org/10.1016/j.pmpp.2023.102006
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d463f53800e86ec805481806a320756
https://doi.org/10.2139/ssrn.4190391
https://doi.org/10.2139/ssrn.4190391
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2170
Application of the CRISPR-Cas prokaryotic immune system for single-stranded RNA targeting will have significant impacts on RNA analysis and engineering. The class 2 Type VI CRISPR-Cas13 system is an RNA-guided RNA-nuclease system capable of binding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d82a50759249eaff48f424e893463149
https://pubmed.ncbi.nlm.nih.gov/32797447
https://pubmed.ncbi.nlm.nih.gov/32797447