Zobrazeno 1 - 10
of 947
pro vyhledávání: '"David E, Nichols"'
Autor:
David E. Nichols
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
At first glance, it appears there is little difference between the molecular structures of methylenedioxymethamphetamine (MDMA), which has an N-methyl attached to its amino group, and methylenedioxyamphetamine (MDA), a primary amine that is recognize
Externí odkaz:
https://doaj.org/article/520a5a368967478185365e18159889d4
Autor:
Jianming Han, Jingying Zhang, Antonina L. Nazarova, Sarah M. Bernhard, Brian E. Krumm, Lei Zhao, Jordy Homing Lam, Vipin A. Rangari, Susruta Majumdar, David E. Nichols, Vsevolod Katritch, Peng Yuan, Jonathan F. Fay, Tao Che
Publikováno v:
Nature. 617:417-425
The κ-opioid receptor (KOR) represents a highly desirable therapeutic target for treating not only pain but also addiction and affective disorders1. However, the development of KOR analgesics has been hindered by the associated hallucinogenic side e
Publikováno v:
Frontiers in Physics, Vol 6 (2018)
The vibrational theory of olfaction is an attempt to describe a possible mechanism for olfaction which is explanatory and provides researchers with a set of principles which permit predictions allowing for structure-odor relations. Similar theories h
Externí odkaz:
https://doaj.org/article/9faa45a462ef4278a953341360ed9f2c
Publikováno v:
Psychedelic Medicine. 1:12-13
Publikováno v:
BMJ. :p981
Autor:
David E, Nichols, Hannes, Walter
Publikováno v:
UnpayWall
ORCID
Microsoft Academic Graph
ORCID
Microsoft Academic Graph
Initial interest in the value of psychedelic drugs (“psychotomimetics”) in psychiatry began in the early 20th century, with explorations of the possibility that mescaline or peyote could produce psychosis-like effects. Over time, interest was foc
Autor:
Can Cao, Ximena Barros-Álvarez, Shicheng Zhang, Kuglae Kim, Marc A. Dämgen, Ouliana Panova, Carl-Mikael Suomivuori, Jonathan Fay, Xiaofang Zhong, Brian E. Krumm, Ryan H. Gumpper, Alpay B. Seven, Michael J. Robertson, Nevan J. Krogan, Ruth Hüttenhain, David E. Nichols, Ron O. Dror, Georgios Skiniotis, Bryan Roth
Publikováno v:
SSRN Electronic Journal.
Autor:
Adam Pigott, Stewart Frescas, John D. McCorvy, Xi-Ping Huang, Bryan L. Roth, David E. Nichols
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 1705-1709 (2012)
A strategy to replace the ethylamine side chain of 2,5-dimethoxy-4-iodoamphetamine (DOI, 1a), and 2,5-dimethoxy-4-bromoamphetamine (DOB, 1b) with a cyclopropylamine moiety was successful in leading to compounds with high affinity at the 5-HT2 family
Externí odkaz:
https://doaj.org/article/e4a4e65219af4ebc8b2d67f16ff7a98c
Autor:
David E. Nichols
Publikováno v:
The Journal of Antibiotics. 73:679-686
Psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine) is an indole-based secondary metabolite produced by numerous species of mushrooms. South American Aztec Indians referred to them as teonanacatl, meaning "god's flesh," and they were used in religiou
Autor:
Can Cao, Ximena Barros-Álvarez, Shicheng Zhang, Kuglae Kim, Marc A. Dämgen, Ouliana Panova, Carl-Mikael Suomivuori, Jonathan F. Fay, Xiaofang Zhong, Brian E. Krumm, Ryan H. Gumpper, Alpay B. Seven, Michael J. Robertson, Nevan J. Krogan, Ruth Hüttenhain, David E. Nichols, Ron O. Dror, Georgios Skiniotis, Bryan L. Roth
Publikováno v:
Neuron. 110:3154-3167.e7
Serotonin (5-hydroxytryptamine [5-HT]) 5-HT2-family receptors represent essential targets for lysergic acid diethylamide (LSD) and all other psychedelic drugs. Although the primary psychedelic drug effects are mediated by the 5-HT