Zobrazeno 1 - 10
of 41
pro vyhledávání: '"David Dominguez-Sola"'
Autor:
Slim Mzoughi, Jia Yi Fong, David Papadopoli, Cheryl M. Koh, Laura Hulea, Paolo Pigini, Federico Di Tullio, Giuseppe Andreacchio, Michal Marek Hoppe, Heike Wollmann, Diana Low, Matias J. Caldez, Yanfen Peng, Denis Torre, Julia N. Zhao, Oro Uchenunu, Gabriele Varano, Corina-Mihaela Motofeanu, Manikandan Lakshmanan, Shun Xie Teo, Cheng Mun Wun, Giovanni Perini, Soo Yong Tan, Chee Bing Ong, Muthafar Al-Haddawi, Ravisankar Rajarethinam, Susan Swee-Shan Hue, Soon Thye Lim, Choon Kiat Ong, Dachuan Huang, Siok-Bian Ng, Emily Bernstein, Dan Hasson, Keng Boon Wee, Philipp Kaldis, Anand Jeyasekharan, David Dominguez-sola, Ivan Topisirovic, Ernesto Guccione
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The transcriptional regulator PRDM15 is expressed at low levels in normal tissues but overexpressed in B-cell lymphomas. Here, the authors show that PRDM15 depletion does not affect adult somatic cell homeostasis but leads to a metabolic crisis which
Externí odkaz:
https://doaj.org/article/9df5fd5400ec47e98903d3b9c0b42cbb
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1629-1639 (2013)
c-Myc oncogenic activity is thought to be mediated in part by its ability to generate DNA replication stress and subsequent genomic instability when deregulated. Previous studies have demonstrated a nontranscriptional role for c-Myc in regulating DNA
Externí odkaz:
https://doaj.org/article/3a7a2ffab33f482e86f588485605ce60
Autor:
Arun Cumpelik, Evan Cody, Samuel Mon-Wei Yu, Emilie K. Grasset, David Dominguez-Sola, Andrea Cerutti, Peter S. Heeger
Publikováno v:
The Journal of Immunology. 210:19-23
T cell–independent (TI) B cell responses to nonprotein Ags involve multiple cues from the innate immune system. Neutrophils express complement receptors and activated neutrophils can release BAFF, but mechanisms effectively linking neutrophil activ
Autor:
Sergio Serrano, David Dominguez-Sola, Francesc Solé, Ferran Sanz, Alberto Orfao, Lourdes Florensa, Andrea Cerutti, Belén Miñana, Josep Lloreta, Cristina Serrano, Leonor Arenillas, Pau Abrisqueta, Esmeralda de la Banda, José Tomás Navarro, Rosa Collado, Elisa Luño, Maria Carmen Vela, Mar Garcia-Garcia, Javier Gimeno, Eulàlia Puigdecanet, Concepción Fernández-Rodríguez, Antonio Salar, Lara Nonell, Beatriz Bellosillo, Ana Ferrer, Blanca Espinet
PDF file 233K, SupplementaryTable S1. Detailed clinical and pathological features of all the cases included in the study; S2. Detailed flow cytometric, cytogenetic and molecular findings of all the cases included in the study; S3. Sequence analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d9c09b9daf8ba7d7bebc6763b001cf
https://doi.org/10.1158/1078-0432.22448786
https://doi.org/10.1158/1078-0432.22448786
Autor:
Sergio Serrano, David Dominguez-Sola, Francesc Solé, Ferran Sanz, Alberto Orfao, Lourdes Florensa, Andrea Cerutti, Belén Miñana, Josep Lloreta, Cristina Serrano, Leonor Arenillas, Pau Abrisqueta, Esmeralda de la Banda, José Tomás Navarro, Rosa Collado, Elisa Luño, Maria Carmen Vela, Mar Garcia-Garcia, Javier Gimeno, Eulàlia Puigdecanet, Concepción Fernández-Rodríguez, Antonio Salar, Lara Nonell, Beatriz Bellosillo, Ana Ferrer, Blanca Espinet
PDF file 132K, Validation of gene expression analysis results by qRT-PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91262f7f57e49c490bd192e01d2505da
https://doi.org/10.1158/1078-0432.22448792.v1
https://doi.org/10.1158/1078-0432.22448792.v1
Autor:
Sergio Serrano, David Dominguez-Sola, Francesc Solé, Ferran Sanz, Alberto Orfao, Lourdes Florensa, Andrea Cerutti, Belén Miñana, Josep Lloreta, Cristina Serrano, Leonor Arenillas, Pau Abrisqueta, Esmeralda de la Banda, José Tomás Navarro, Rosa Collado, Elisa Luño, Maria Carmen Vela, Mar Garcia-Garcia, Javier Gimeno, Eulàlia Puigdecanet, Concepción Fernández-Rodríguez, Antonio Salar, Lara Nonell, Beatriz Bellosillo, Ana Ferrer, Blanca Espinet
Purpose: According to current diagnostic criteria, mantle cell lymphoma (MCL) encompasses the usual, aggressive variants and rare, nonnodal cases with monoclonal asymptomatic lymphocytosis, cyclin D1–positive (MALD1). We aimed to understand the bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678e72914b01e06a94671942dbd4615b
https://doi.org/10.1158/1078-0432.c.6521486
https://doi.org/10.1158/1078-0432.c.6521486
Autor:
Dirk Homann, Arun Cumpelik, Mark P. Roberto, Sergio A. Lira, Farideh Ordikhani, David Dominguez-Sola, Gabriele Varano, Zhengxiang He, Yuan Hu, Peter S. Heeger, Dávid Héja
Publikováno v:
Nature immunology
Maturation of B cells within germinal centers (GCs) generates diversified B cell pools and high-affinity B cell antigen receptors (BCRs) for pathogen clearance. Increased receptor affinity is achieved by iterative cycles of T cell–dependent, affini
Autor:
Heike Wollmann, David Papadopoli, Ravisankar Rajarethinam, Giovanni Perini, Michal Marek Hoppe, Laura Hulea, Soo Yong Tan, Emily Bernstein, Susan Swee Shan Hue, Choon Kiat Ong, Siok Bian Ng, Soon Thye Lim, Slim Mzoughi, Cheryl M. Koh, Ivan Topisirovic, Federico Di Tullio, Manikandan Lakshmanan, Corina Mihaela Motofeanu, Ernesto Guccione, Cheng Mun Wun, Oro Uchenunu, Chee Bing Ong, David Dominguez-Sola, Shun Xie Teo, Diana Low, Giuseppe Andreacchio, Gabriele Varano, Dachuan Huang, Muthafar Al-Haddawi, Paolo Pigini, Denis Torre, Y Peng, Anand D. Jeyasekharan, Julia N. Zhao, Philipp Kaldis, Jia Yi Fong, Matias J. Caldez, Keng Boon Wee, Dan Hasson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
PRDM (PRDI-BF1 and RIZ homology domain containing) family members are sequence-specific transcriptional regulators involved in cell identity and fate determination, often dysregulated in cancer. The PRDM15 gene is of particular interest, given its lo
Autor:
Rosa Vinas-Castells, Alja Kozulic-Pirher, Tomás Aparicio, Sandra Casas Recasens, Mark P. Roberto, Rachel Sue, Francisco Martinez, Nuria López-Bigas, Jean Gautier, David Dominguez-Sola
Publikováno v:
Cancer Research. 82:1517-1517
Oncogene deregulation triggers replication stress, which can be detected in precancerous lesions and is a source of subsequent genomic instability in cancer. Studies on the mechanisms underlying DNA replication stress caused by frequently deregulated
Autor:
Jongkuen, Lee, David, Dominguez-Sola
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2267
Cell cycle progression, or its arrest upon checkpoint activation, is directed by a complex array of cellular processes dependent on the diffusion of chemical signals. These signals regulate the onset of each cell cycle phase and prevent undesired pha