Zobrazeno 1 - 10
of 13
pro vyhledávání: '"David DiSilvestro"'
Autor:
Tuo Deng, Joey Liu, Yanru Deng, Laurie Minze, Xiang Xiao, Valerie Wright, Richeng Yu, Xian C. Li, Alecia Blaszczak, Stephen Bergin, David DiSilvestro, Ryan Judd, David Bradley, Michael Caligiuri, Christopher J. Lyon, Willa A. Hsueh
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Obesity is associated with inflammation in adipose tissue, characterized by a shift in local T cell subsets. Here the authors show that loss of MHCII expression on adipocytes increases levels of immunosuppressive regulatory T cells in adipose tissue,
Externí odkaz:
https://doaj.org/article/f06d437e5dce45deabca2a777dc8a491
Autor:
Ouliana Ziouzenkova, David DiSilvestro, Rumana Yasmeen, Andrei Maiseyeu, Paolo Fadda, Kefeng Yang, Naresh C. Bal, Lu Xu, Muthu Periasamy, Qiwen Shen, Jacob H. Leung, Devan Kowdley, Aejin Lee
Publikováno v:
The Journal of endocrinology. 239(3)
Adipokine leptin regulates neuroendocrine circuits that control energy expenditure, thermogenesis and weight loss. However, canonic regulators of leptin secretion, such as insulin and malonyl CoA, do not support these processes. We hypothesize that e
Autor:
Valerie P. Wright, Willa A. Hsueh, Tuo Deng, Ryan T. Judd, Michael A. Caligiuri, Xian Chang Li, Joey Liu, Stephen M. Bergin, Richeng Yu, Yanru Deng, David Bradley, David DiSilvestro, Christopher J. Lyon, Laurie J. Minze, Alecia Blaszczak, Xiang Xiao
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Obesity leads to a switch in subsets of CD4+ T cell in adipose tissue, characterized by an increase in IFNγ producing Th1 cells and a decrease in anti-inflammatory regulatory T (Treg) cells, which impairs systemic insulin sensitivity. What signals t
Autor:
Mark L. Failla, Jaisa L. Thomas, Ouliana Ziouzenkova, Liubov V. Gushchina, Qiwen Shen, David DiSilvestro, Chureeporn Chitchumroonchokchai
Publikováno v:
Molecular Nutrition & Food Research. 58:239-247
Scope: Three fluorescence biosensors were developed based on a 3T3-L1 preadipocyte line that stably expressed Nfkb-RE/GFP, Fabp4-P/CFP, and Nrf2-P/YFP fluorescent reporters. We hypothesized that nutraceuticals’ inflammatory, adipogenic, and antioxi
Autor:
Ouliana Ziouzenkova, Emiliano Melgar-Bermudez, Chen Gilor, David DiSilvestro, Anuradha Kalyanasundaram, L. James Lee, Rumana Yasmeen, Paolo Fadda
Publikováno v:
PloS one, vol 11, iss 4
PLoS ONE, Vol 11, Iss 4, p e0153198 (2016)
PLoS ONE
PLoS ONE, Vol 11, Iss 4, p e0153198 (2016)
PLoS ONE
The neuroendocrine effects of leptin on metabolism hold promise to be translated into a complementary therapy to traditional insulin therapy for diabetes and obesity. However, injections of leptin can provoke inflammation. We tested the effects of le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158b761ae095912899d3606233de6a01
https://escholarship.org/uc/item/0vr493gr
https://escholarship.org/uc/item/0vr493gr
Publikováno v:
Food and Chemical Toxicology. 45:1293-1300
Kava, like a number of herbals, has been associated with causing liver damage based on limited evidence. In contrast, the present study found that in rats, 3 mo feedings of two types of kava extracts (an acetone extract and an ethanol extract of the
Autor:
Ouliana Ziouzenkova, Jennifer M. Petrosino, Emiliano Melgar-Bermudez, David DiSilvestro, Ayat Aldoori, Alexandra Wells
Publikováno v:
Hormone molecular biology and clinical investigation. 19(1)
Abdominal fat formation has become a permanent risk factor for metabolic syndrome and various cancers in one-third of the world’s population of obese and even lean patients. Formation of abdominal fat involves additional mechanisms beyond an imbala
Publikováno v:
The FASEB Journal. 28
Publikováno v:
Nutrients
Nutrients, Vol 6, Iss 3, Pp 950-973 (2014)
Nutrients, Vol 6, Iss 3, Pp 950-973 (2014)
In this review, we summarize recent advances in understanding vitamin A-dependent regulation of sex-specific differences in metabolic diseases, inflammation, and certain cancers. We focus on the characterization of the aldehyde dehydrogenase-1 family
Autor:
David DiSilvestro, Ouliana Ziouzenkova, Keith Fluegge, Gregg Duester, Rumana Yasmeen, Fangping Yang, Joseph Meyers
Publikováno v:
The FASEB Journal. 26
Abnormal immunoglobulin (Ig) production underlines hematological cancers. Studies show association of these cancers with obesity. However, it is unclear how high-fat (HF) diets influence Ig levels ...