Zobrazeno 1 - 5
of 5
pro vyhledávání: '"David Dermot Patrick Laffan"'
Autor:
Erwin Irdam, Christopher J. Welch, Aaron S. Cote, Jean W. Tom, Pierre Boulas, Joel M. Hawkins, Kenneth M. Wells, Charles D. Papageorgiou, David Dermot Patrick Laffan, Margaret M. Faul, Purdie Mark, Rahn McKeown, Scott A. May, Steven J. Wittenberger, Srinivas Tummala, Kevin D. Seibert, Nicholas Murray Thomson, Frederick Hicks, Antonio Christian Ferretti, Paul Frank Fernandez, Keith Horspool, Shailendra Bordawekar, Bing-Shiou Yang
Publikováno v:
Organic Process Research & Development. 21:414-419
The creation of the Enabling Technologies Consortium (ETC) is described. The ETC fosters precompetitive collaborations aimed at the development and evaluation of new enabling technologies for pharmaceutical research and development, with an initial f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf381c2d7be47db5f43a4d433973b1db
https://doi.org/10.1021/acs.oprd.6b00427
https://doi.org/10.1021/acs.oprd.6b00427
Autor:
Guy C. Lloyd-Jones, David Dermot Patrick Laffan, Jennifer L. Slaughter, Philip D. Wall, Alexandra J. Parker
Publikováno v:
Tetrahedron. 62:11402-11412
Dibenzylideneacetone (8) reacts with in situ-generated allylindium halide reagents to yield the product of a homoallyl-cyclopropanation reaction: 2-(3″-butenyl)-1,1-bis[(E)-2′-phenylethenyl]cyclopropane (9), which proceeds via step-wise cleavage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49367d495c4e3223bca3b807f378ad6f
https://doi.org/10.1016/j.tet.2006.05.003
https://doi.org/10.1016/j.tet.2006.05.003
Publikováno v:
Tetrahedron Letters. 45:6541-6543
Attempts to convert a propargylic alcohol bearing an imidazolone substituent to the corresponding aldehyde under Parikh-Doering conditions gave an alpha,beta-unsaturated-beta-methylsulfanyl aldehyde, which cyclised under mildly acidic conditions. (C)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::182f76c8e2b7939d88e56fd42a1285ec
https://doi.org/10.1016/j.tetlet.2004.07.062
https://doi.org/10.1016/j.tetlet.2004.07.062
Autor:
David Dermot Patrick Laffan, Ian Shepperson, Teresa Martínez del Campo, Jennifer L. Slaughter, Guy C. Lloyd-Jones, Erik Kühnel
Publikováno v:
Angewandte Chemie (International ed. in English). 46(37)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1bba2cb3ce23ea3e5adf5d9de15b7a
https://pubmed.ncbi.nlm.nih.gov/17691089
https://pubmed.ncbi.nlm.nih.gov/17691089
Publikováno v:
ChemInform. 37
The purpose of this perspective is to indicate the range of chemistries used in the manufacture of drug candidate molecules and to highlight certain gaps in current technologies. To do this a survey was carried out of chemical syntheses within the Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f4c0d5bc1630fe5f8ed36027fe5f4c
https://doi.org/10.1002/chin.200642267
https://doi.org/10.1002/chin.200642267