Zobrazeno 1 - 10
of 12
pro vyhledávání: '"David De Coster"'
Autor:
Stefanie Roberfroid, David De Coster, Lise Dieltjens, Hans Steenackers, Kevin R. Foster, Bram Lories
Publikováno v:
Current Biology
Bacteria use complex regulatory networks to cope with stress, but the function of these networks in natural habitats is poorly understood. The competition sensing hypothesis states that bacterial stress response systems can serve to detect ecological
Autor:
Christopher McGuigan, Thijs Van Leemputte, Xabier Villanueva, Jennifer Richards, Mandy Wootton, Fabrizio Pertusati, Elisa Pileggi, Leentje Persoons, Michaela Serpi, Hans Steenackers, Dirk Daelemans, David De Coster
Publikováno v:
The Journal of antimicrobial chemotherapy. 75(10)
Objectives Following a drug repurposing approach, we aimed to investigate and compare the antibacterial and antibiofilm activities of different classes of phosphate prodrugs (HepDirect, cycloSal, SATE and mix SATE) of antiviral and anticancer FDA-app
Autor:
Sigrid C. J. De Keersmaecker, Inge Thijs, Jos Vanderleyden, Stefanie Roberfroid, Hans Steenackers, Kathleen Marchal, Kim Hermans, David De Coster, Gwendoline Kint
Publikováno v:
BMC Genomics
BMC GENOMICS
BMC GENOMICS
Background: Biofilm formation is an important survival strategy of Salmonella in all environments. By mutant screening, we showed a knock-out mutant of fabR, encoding a repressor of unsaturated fatty acid biosynthesis (UFA), to have impaired biofilm
Autor:
Stefanie Roberfroid, Kim Hermans, David De Coster, Sigrid C. J. De Keersmaecker, T.L. Anh Nguyen, Jos Vanderleyden, Geert Schoofs, Tine Verhoeven
Publikováno v:
Journal of Microbiological Methods. 84:467-478
Bacterial biofilm formation is an important cause of environmental persistence of food-borne pathogens, such as Salmonella Typhimurium. As the ensemble of bacterial cells within a biofilm represents different physiological states, even for monospecie
Autor:
B. Savaliya, Sigrid C. J. De Keersmaecker, David De Coster, Jozef Vanderleyden, Erik V. Van der Eycken, Dirk De Vos, Ami De Weerdt, Anamik Shah, Denis S. Ermolat'ev, Hans Steenackers
Publikováno v:
Journal of medicinal chemistry. 54(2)
A library of 112 4(5)-aryl-2-amino-1H-imidazoles, 4,5-diphenyl-2-amino-1H-imidazoles, and N1-substituted 4(5)-phenyl-2-aminoimidazoles was synthesized and tested for the antagonistic effect against biofilm formation by Salmonella Typhimurium and Pseu
Autor:
Anamik Shah, Dirk De Vos, B. Savaliya, Sigrid C. J. De Keersmaecker, Ami De Weerdt, Jozef Vanderleyden, Hans Steenackers, Denis S. Ermolat'ev, Erik V. Van der Eycken, David De Coster
Publikováno v:
Bioorganicmedicinal chemistry. 19(11)
A library of 80 1-substituted 2-hydroxy-2-aryl-2,3-dihydro-imidazo[1,2-a]pyrimidinium salts and 54 2N-substituted 4(5)-aryl-2-amino-1H-imidazoles was synthesized and tested for the antagonistic effect against biofilm formation by Salmonella Typhimuri
Autor:
Sigrid C. J. De Keersmaecker, Inge Thijs, Jos Vanderleyden, Hui Zhao, David De Coster, Ami De Weerdt, Kathleen Marchal, Geert Schoofs, Michael McClelland, Kristof Engelen
Publikováno v:
Cell research. 20(8)
Autor:
Sigrid C. J. De Keersmaecker, Jos Vanderleyden, Kathleen Marchal, Gwendoline Kint, David De Coster
Publikováno v:
BMC MICROBIOLOGY
BMC Microbiology
BMC Microbiology, Vol 10, Iss 1, p 276 (2010)
BMC Microbiology
BMC Microbiology, Vol 10, Iss 1, p 276 (2010)
Background LuxS is the synthase enzyme of the quorum sensing signal AI-2. In Salmonella Typhimurium, it was previously shown that a luxS deletion mutant is impaired in biofilm formation. However, this phenotype could not be complemented by extracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0e9c6fdd1819483913dfe2c727359a
https://lirias.kuleuven.be/handle/123456789/625585
https://lirias.kuleuven.be/handle/123456789/625585
Autor:
David De Coster, Gwendoline Kint, Geert Schoofs, Sigrid C. J. De Keersmaecker, Jos Vanderleyden, K. Sonck
Publikováno v:
BMC Microbiology, Vol 9, Iss 1, p 198 (2009)
BMC Microbiology
BMC Microbiology
Background Quorum sensing is a term describing a bacterial communication system mediated by the production and recognition of small signaling molecules. The LuxS enzyme, catalyzing the synthesis of AI-2, is conserved in a wide diversity of bacteria.
Autor:
Dirk De Vos, Jeremy Levin, Kathleen Marchal, Hans Steenackers, Tine Verhoeven, Hui Zhao, Joost Janssens, Sigrid C. J. De Keersmaecker, Edith Gellens, David De Coster, Kim Hermans, Jos Vanderleyden, Stijn Robijns
Publikováno v:
Applied and environmental microbiology. 74(21)
Salmonella enterica serovar Typhimurium is a main cause of bacterial food-borne diseases. As Salmonella can form biofilms in which it is better protected against antimicrobial agents on a wide diversity of surfaces, it is of interest to explore ways