Zobrazeno 1 - 10
of 255
pro vyhledávání: '"David Dawson"'
Autor:
Olga A. Mareninova, Dustin L. Dillon, Carli J.M. Wightman, Iskandar Yakubov, Toshimasa Takahashi, Herbert Y. Gaisano, Keith Munson, Masaki Ohmuraya, David Dawson, Ilya Gukovsky, Anna S. Gukovskaya
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 599-622 (2022)
Background: Autophagosome, the central organelle in autophagy process, can assemble via canonical pathway mediated by LC3-II, the lipidated form of autophagy-related protein LC3/ATG8, or noncanonical pathway mediated by the small GTPase Rab9. Canonic
Externí odkaz:
https://doaj.org/article/11feff5cad444a05b90bf2cb94aaf905
Autor:
Wayne M. Koster, Kim Aarestrup, Kim Birnie-Gauvin, Ben Church, David Dawson, Jarod Lyon, Justin O’Connor, David Righton, Denis Rose, Håkan Westerberg, Ivor Stuart
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Anguillid eel populations have declined dramatically over the last 50 years in many regions of the world, and numerous species are now under threat. A critical life-history phase is migration from freshwater to distant oceans, culminating in
Externí odkaz:
https://doaj.org/article/1d827cd724044680bf643fcf6722f1c8
Autor:
Georgina Mancinelli, Carolina Torres, Nancy Krett, Jessica Bauer, Karla Castellanos, Ron McKinney, David Dawson, Grace Guzman, Rosa Hwang, Sam Grimaldo, Paul Grippo, Barbara Jung
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Pancreatic ductal adenocarcinoma (PDAC) has extensive stromal involvement and remains one of the cancers with the highest mortality rates. Activin A has been implicated in colon cancer and its stroma but its role in the stroma of PDAC has no
Externí odkaz:
https://doaj.org/article/83e0be2dcf7e423bbd2aa5ad936461d6
Autor:
Emily O'Donnell, Colin Thorne, Sangaralingam Ahilan, Scott Arthur, Stephen Birkinshaw, David Butler, David Dawson, Glyn Everett, Richard Fenner, Vassilis Glenis, Leon Kapetas, Chris Kilsby, Vladimir Krivtsov, Jessica Lamond, Shaun Maskrey, Greg O'Donnell, Karen Potter, Kim Vercruysse, Tudorel Vilcan, Nigel Wright
Publikováno v:
Blue-Green Systems, Vol 2, Iss 1, Pp 28-45 (2019)
Achieving urban flood resilience at local, regional and national levels requires a transformative change in planning, design and implementation of urban water systems. Flood risk, wastewater and stormwater management should be re-envisaged and transf
Externí odkaz:
https://doaj.org/article/4c3da25859a242c4a5df1ae641b534d3
Publikováno v:
Echo Research and Practice, Vol 3, Iss 2, Pp 29-34 (2016)
Background: In this study, we investigate the correlation between reduced global longitudinal peak systolic strain (GLPSS) and the SYNTAX score (SS) in patients undergoing coronary angiography. Methods: We examined 71 patients undergoing both echoca
Externí odkaz:
https://doaj.org/article/2d72e20bf4c2463ab1910d9d4c8fedd8
Autor:
Olga A. Mareninova, Matthias Sendler, Sudarshan Ravi Malla, Iskandar Yakubov, Samuel W. French, Elmira Tokhtaeva, Olga Vagin, Viola Oorschot, Renate Lüllmann-Rauch, Judith Blanz, David Dawson, Judith Klumperman, Markus M. Lerch, Julia Mayerle, Ilya Gukovsky, Anna S. Gukovskaya
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 6, Pp 678-694 (2015)
Background & Aims: The pathogenic mechanism of pancreatitis is poorly understood. Recent evidence implicates defective autophagy in pancreatitis responses; however, the pathways mediating impaired autophagy in pancreas remain largely unknown. Here, w
Externí odkaz:
https://doaj.org/article/cb4a33f8eeb6420680ed96b3e0cadf95
Autor:
Richard Fenner, Emily O’Donnell, Sangaralingam Ahilan, David Dawson, Leon Kapetas, Vladimir Krivtsov, Sikhululekile Ncube, Kim Vercruysse
Publikováno v:
Water, Vol 11, Iss 5, p 1082 (2019)
Preliminary results of the UK Urban Flood Resilience research consortium are presented and discussed, with the work being conducted against a background of future uncertainties with respect to changing climate and increasing urbanization. Adopting a
Externí odkaz:
https://doaj.org/article/73d3dda129b5474db8e317a2ffa384c6
Autor:
Julia Grapsa, J. Simon R. Gibbs, Petros Nihoyannopoulos, Luke S. Howard, Navroz D. Masani, John B. Chambers, Michael Bellamy, David Dawson
Publikováno v:
European Respiratory Review, Vol 21, Iss 125, Pp 239-248 (2012)
Patients with suspected pulmonary hypertension (PH) should be evaluated using a multimodality approach to ensure that they receive a correct diagnosis. The series of investigations required includes clinical evaluation, noninvasive imaging techniques
Externí odkaz:
https://doaj.org/article/d75dffe5def9421a820c5cfc1b47d7f0
Autor:
Shi-He Liu, Donald D Rao, John Nemunaitis, Neil Senzer, Guisheng Zhou, David Dawson, Marie-Claude Gingras, Zhaohui Wang, Richard Gibbs, Michael Norman, Nancy S Templeton, Francesco J Demayo, Bert O'Malley, Robbi Sanchez, William E Fisher, F Charles Brunicardi
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e40452 (2012)
Pancreatic and duodenal homeobox-1 (PDX-1) is a transcription factor that regulates insulin expression and islet maintenance in the adult pancreas. Our recent studies demonstrate that PDX-1 is an oncogene for pancreatic cancer and is overexpressed in
Externí odkaz:
https://doaj.org/article/e7af8a896079435480ccab9f9969443c
Autor:
Inês Zimbarra Cabrita, Julia Grapsa, David Dawson, Fausto J. Pinto, J. Simon R. Gibbs, Petros Nihoyannopoulos
Publikováno v:
Revista Portuguesa de Cardiologia, Vol 31, Iss 10, Pp 683-684 (2012)
Externí odkaz:
https://doaj.org/article/4a71f544d5414cef84ad6dd05d85bab0