Zobrazeno 1 - 10
of 396
pro vyhledávání: '"David D.L. Bowtell"'
Autor:
Omali Pitiyarachchi, Yeh Chen Lee, Hao-Wen Sim, Sivatharsny Srirangan, Cristina Mapagu, Judy Kirk, Paul R. Harnett, Rosemary L. Balleine, David D.L. Bowtell, Goli Samimi, Alison H. Brand, Deborah J. Marsh, Philip Beale, Lyndal Anderson, Natalie Bouantoun, Pamela Provan, Susan J. Ramus, Anna DeFazio, Michael Friedlander
Publikováno v:
Translational Oncology, Vol 31, Iss , Pp 101638- (2023)
Background: Somatic pathogenic variants (PVs) in homologous recombination DNA repair (HR)-related genes found in high-grade serous ovarian carcinomas (HGSC) are not well-characterised in older patients (≥70 years). This may reflect low testing rate
Externí odkaz:
https://doaj.org/article/05e8b7eb7bab4b7a9ce7d16d06ef35d0
Publikováno v:
Journal of Clinical Oncology. 41:1770-1773
Autor:
Nicola S. Meagher, Phineas Hamilton, Katy Milne, Shelby Thornton, Bronwyn Harris, Ashley Weir, Jennifer Alsop, Christiani Bisinoto, James D. Brenton, Angela Brooks-Wilson, Derek S. Chiu, Kara L. Cushing-Haugen, Sian Fereday, Dale W. Garsed, Simon A. Gayther, Aleksandra Gentry-Maharaj, Blake Gilks, Mercedes Jimenez-Linan, Catherine J. Kennedy, Nhu D. Le, Anna M. Piskorz, Marjorie J. Riggan, Mitul Shah, Naveena Singh, Aline Talhouk, Martin Widschwendter, David D.L. Bowtell, Francisco J. Candido dos Reis, Linda S. Cook, Renée T. Fortner, María J. García, Holly R. Harris, David G. Huntsman, Anthony N. Karnezis, Martin Köbel, Usha Menon, Paul D.P. Pharoah, Jennifer A. Doherty, Michael S. Anglesio, Malcolm C. Pike, Celeste Leigh Pearce, Michael L. Friedlander, Anna DeFazio, Brad H. Nelson, Susan J. Ramus
Publikováno v:
Gynecologic Oncology. 168:23-31
Mucinous ovarian carcinoma (MOC) is a rare histotype of ovarian cancer, with low response rates to standard chemotherapy, and very poor survival for patients diagnosed at advanced stage. There is a limited understanding of the MOC immune landscape, a
Autor:
Minh Tung Phung, Penelope M. Webb, Anna DeFazio, Sian Fereday, Alice W. Lee, David D.L. Bowtell, Peter A. Fasching, Ellen L. Goode, Marc T. Goodman, Beth Y. Karlan, Jenny Lester, Keitaro Matsuo, Francesmary Modugno, James D. Brenton, Toon Van Gorp, Paul D.P. Pharoah, Joellen M. Schildkraut, Karen McLean, Rafael Meza, Bhramar Mukherjee, Jean Richardson, Bronwyn Grout, Anne Chase, Cindy McKinnon Deurloo, Kathryn L. Terry, Gillian E. Hanley, Malcolm C. Pike, Andrew Berchuck, Susan J. Ramus, Celeste Leigh Pearce
Publikováno v:
Gynecologic Oncology. 168:68-75
The presence of macroscopic residual disease after primary cytoreductive surgery (PCS) is an important factor influencing survival for patients with high-grade serous ovarian cancer (HGSC). More research is needed to identify factors associated with
Autor:
Paula Cunnea, Edward W. Curry, Elizabeth L. Christie, Katherine Nixon, Chun Hei Kwok, Ahwan Pandey, Ratri Wulandari, Kerstin Thol, Jennifer Ploski, Cristina Morera-Albert, Stephen McQuaid, Jingky Lozano-Kuehne, James J. Clark, Jonathan Krell, Euan A. Stronach, Iain A. McNeish, David D.L. Bowtell, Christina Fotopoulou
Limited evidence exists on the impact of spatial and temporal heterogeneity of high-grade serous ovarian cancer (HGSOC) on tumor evolution, clinical outcomes, and surgical operability. We perform systematic multi-site tumor mapping at presentation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32db0edd6d3e730d4cc771fa803b5e7e
http://hdl.handle.net/10044/1/104492
http://hdl.handle.net/10044/1/104492
Autor:
Matthew Meyerson, Cory M. Johannessen, Levi A. Garraway, Anthony Letai, Kristopher A. Sarosiek, David D.L. Bowtell, Ursula A. Matulonis, Federica Piccioni, Andrew D. Cherniack, Felice J. Liang, Joan Montero, Jennifer L. Guerriero, Jeremy Ryan, Patrick D. Bhola, Ioannis K. Zervantonakis, Weiqun Zhang, Maya K. Gelbard, Adam G. Presser, Guo Wei, Matthew G. Rees, Sasha Pantel, Yenarae Lee, Amy Goodale, Mukta Bagul, Elizabeth L. Christie, Yvonne Y. Li, Ofir Cohen, Maria B. Baco, Elizabeth H. Stover
ORF overexpression screen data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b44e9f873f533f0eaf2031c1822c66
https://doi.org/10.1158/1541-7786.22512715
https://doi.org/10.1158/1541-7786.22512715
Autor:
Matthew Meyerson, Cory M. Johannessen, Levi A. Garraway, Anthony Letai, Kristopher A. Sarosiek, David D.L. Bowtell, Ursula A. Matulonis, Federica Piccioni, Andrew D. Cherniack, Felice J. Liang, Joan Montero, Jennifer L. Guerriero, Jeremy Ryan, Patrick D. Bhola, Ioannis K. Zervantonakis, Weiqun Zhang, Maya K. Gelbard, Adam G. Presser, Guo Wei, Matthew G. Rees, Sasha Pantel, Yenarae Lee, Amy Goodale, Mukta Bagul, Elizabeth L. Christie, Yvonne Y. Li, Ofir Cohen, Maria B. Baco, Elizabeth H. Stover
Supplementary detailed methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1ed5fd1d23addc36ebc8885749e056
https://doi.org/10.1158/1541-7786.22512691
https://doi.org/10.1158/1541-7786.22512691
Autor:
Kylie L. Gorringe, Ian G. Campbell, Kaylene J. Simpson, Richard B. Pearson, David G. Huntsman, David D.L. Bowtell, Susan J. Ramus, Felix Hilpert, Andreas du Bois, Jacobus Pfisterer, Stefan Kommoss, Anna Wu, Malcolm C. Pike, Celeste Leigh Pearce, Jacek Gronwald, Jan Lubinski, Aleksandra Gentry-Maharaj, Usha Menon, Maria P. Intermaggio, Sian Fereday, Nadia Traficante, Joshy George, Michael S. Anglesio, Karen E. Sheppard, Sally J. Davis
MetaCore analysis results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f650e4c7d4802f3d3168ef36084b94
https://doi.org/10.1158/1535-7163.22501114
https://doi.org/10.1158/1535-7163.22501114
Autor:
Kylie L. Gorringe, Ian G. Campbell, Kaylene J. Simpson, Richard B. Pearson, David G. Huntsman, David D.L. Bowtell, Susan J. Ramus, Felix Hilpert, Andreas du Bois, Jacobus Pfisterer, Stefan Kommoss, Anna Wu, Malcolm C. Pike, Celeste Leigh Pearce, Jacek Gronwald, Jan Lubinski, Aleksandra Gentry-Maharaj, Usha Menon, Maria P. Intermaggio, Sian Fereday, Nadia Traficante, Joshy George, Michael S. Anglesio, Karen E. Sheppard, Sally J. Davis
Identification of genomic alterations defining ovarian carcinoma subtypes may aid the stratification of patients to receive targeted therapies. We characterized high-grade serous ovarian carcinoma (HGSC) for the association of amplified and overexpre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f5876dd86cd7bd57d9f342ef0b7a208
https://doi.org/10.1158/1535-7163.c.6536680.v1
https://doi.org/10.1158/1535-7163.c.6536680.v1
Autor:
David D.L. Bowtell, Georgia Chenevix-Trench, Anna deFazio, Michael J. Birrer, Raghwa Sharma, Peter Russell, Nadia Traficante, Sian Fereday, Bianca Locandro, Lisa Simms, Nic Waddell, Richard Tothill, Anna V. Tinker, Joshy George, Jeremy M. Arnold, Michael S. Anglesio
Approximately, 10% to 15% of serous ovarian tumors fall into the category designated as tumors of low malignant potential (LMP). Like their invasive counterparts, LMP tumors may be associated with extraovarian disease, for example, in the peritoneal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03781d98b99c41ca8e5b1e997df72fcd
https://doi.org/10.1158/1541-7786.c.6541827.v1
https://doi.org/10.1158/1541-7786.c.6541827.v1