Zobrazeno 1 - 10 of 143 pro vyhledávání: '"David D. Ralph"'
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Metabolomic Signatures Associated With Pulmonary Arterial Hypertension Outcomes
Autor: Hongyang Pi, Lu Xia, David D. Ralph, Samuel G. Rayner, Ali Shojaie, Peter J. Leary, Sina A. Gharib
Publikováno v: Circulation research.
Background: Pulmonary arterial hypertension (PAH) is a complex disease characterized by progressive right ventricular (RV) failure leading to significant morbidity and mortality. Investigating metabolic features and pathways associated with RV dilati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f6c6944c2122d27557db6a22ecd164
https://pubmed.ncbi.nlm.nih.gov/36597887
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3
Circulating markers of inflammation and angiogenesis and clinical outcomes across subtypes of pulmonary arterial hypertension
Autor: Kellen Hirsch, Stephanie Nolley, David D. Ralph, Ying Zheng, William A. Altemeier, Christopher J. Rhodes, Nicholas W. Morrell, Martin R. Wilkins, Peter J. Leary, Samuel G. Rayner
Publikováno v: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
Subtypes of pulmonary arterial hypertension (PAH) differ in both fundamental disease features and clinical outcomes. Angiogenesis and inflammation represent disease features that may differ across subtypes and are of special interest in connective ti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f61438127173be49e3b9f8bec9572aa
https://pubmed.ncbi.nlm.nih.gov/36470771
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4
A Survey-based Estimate of COVID-19 Incidence and Outcomes among Patients with Pulmonary Arterial Hypertension or Chronic Thromboembolic Pulmonary Hypertension and Impact on the Process of Care
Autor: David D. Ralph, Sam G. Rayner, Roham T. Zamanian, Charles D. Burger, Daniel C. Grinnan, Peter J. Leary, Corey E. Ventetuolo, Zeenat Safdar, Joshua D. Lee, John J. Ryan, Genecelle B. Delossantos
Publikováno v: Annals of the American Thoracic Society
Rationale: Patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) typically undergo frequent clinical evaluation. The incidence and outcomes of coronavirus disease (COVID-19) and its impact on ro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21ab7e0be322c8f4564a2bbeef39ce6
http://europepmc.org/articles/PMC7706604
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5
Thyroid-stimulating hormone and mortality in pulmonary arterial hypertension
Autor: Hongyang Pi, Samuel G Rayner, David D Ralph, Stephanie Nolley, Lia M Barros, Zachary L Steinberg, Peter J Leary
Publikováno v: BMJ Open Respiratory Research. 9:e001348
IntroductionPulmonary arterial hypertension (PAH) remains a serious and life-threatening illness. Thyroid dysfunction is relatively understudied in individuals with PAH but is known to affect cardiac function and vascular tone in other diseases. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052ccd881b3bc66e5ab0cf50012c215c
https://doi.org/10.1136/bmjresp-2022-001348
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6
Associations of Angiopoietins With Heart Failure Incidence and Severity
Autor: Joao A.C. Lima, Samuel G. Rayner, Richard A. Kronmal, Peter J. Leary, David A. Bluemke, Steven M. Kawut, David D. Ralph, Brandon Peplinski, Brian A. Houston, Zachary L. Steinberg, Ryan J. Tedford, Todd M. Kolb
Publikováno v: J Card Fail
BACKGROUND: Angiopoietin-1 and 2 (Ang1, Ang2) are important mediators of angiogenesis. Angiopoietin levels are perturbed in cardiovascular disease, but it is unclear whether angiopoietin signaling is causative, an adaptive response, or merely epiphen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95545296f1e8e24f220a710fcc46e7d1
https://pubmed.ncbi.nlm.nih.gov/33872759
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10
Histamine H2 Receptor Polymorphisms, Myocardial Transcripts, and Heart Failure (from the Multi-Ethnic Study of Atherosclerosis and Beta-Blocker Effect on Remodeling and Gene Expression Trial)
Autor: Peter M. Buttrick, Wayne Minobe, Noel S. Weiss, Eric V. Krieger, Kenneth L. Jones, Ryan J. Tedford, Joao A.C. Lima, Richard A. Kronmal, Steven M. Kawut, David D. Ralph, David A. Bluemke, Michael R. Bristow, David P. Kao, Peter J. Leary
Publikováno v: The American Journal of Cardiology. 121:256-261
Myocardial H 2 receptor activation contributes to heart failure (HF) in preclinical models, and H 2 receptor antagonists are associated with decreased HF incidence. This study evaluated whether H 2 histamine receptor (HRH2) single nucleotide polymorp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b50e7f05450a9e435f9d42cf5e9b4f
https://doi.org/10.1016/j.amjcard.2017.10.016
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