Dynamic secretome of bone marrow-derived stromal cells reveals a cardioprotective biochemical cocktail

Autor: Onur Kilic, Junaid Afzal, Jeffrey L. Spees, Andre Levchenko, Kshitiz, Yasir Suhail, David D. Ellison, Laura Woo

Publikováno v: Proceedings of the National Academy of Sciences. 116:14374-14383

Transplanted stromal cells have demonstrated considerable promise as therapeutic agents in diverse disease settings. Paracrine signaling can be an important mediator of these therapeutic effects at the sites of acute or persistent injury and inflamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc8bce96b08220be34ebb01c5b320a3
https://doi.org/10.1073/pnas.1902598116

Using Lab-on-a-Chip Technologies for Stem Cell Biology

Autor: Andre Levchenko, Kshitiz Gupta, Deok Ho Kim, Christopher Smith, David D. Ellison

Publikováno v: Stem Cell Biology and Regenerative Medicine ISBN: 9781607618591

The introduction of microtechnology and microfluidic platforms for cell culture can dramatically enhance the pace of stem cell research. With the use of microfluidic-based techniques, extracellular microenvironments can be controlled in a precise man

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca8625f7e9c75d9d824b2190d3a0f8db
https://doi.org/10.1007/978-1-60761-860-7_30

Assessing and improving the accuracy of detecting protein adaptation with the TreeSAAP analytical software

Autor: David D. Ellison, David A. McClellan

Publikováno v: International journal of bioinformatics research and applications. 6(2)

TreeSAAP has been used in a variety of protein studies for detecting adaptation in terms of the physicochemical properties involved in amino acid replacement. The accuracy of TreeSAAP was here tested using simulated protein-coding DNA data. A samplin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8859c74befbfa8e00c90c9554abddb1
https://pubmed.ncbi.nlm.nih.gov/20223735

Spatiotemporal modeling of molecular holograms.

Autor: Qiu X; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA; Department of Computer Science, Stanford University, Stanford, CA 94305, USA; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA. Electronic address: xiaojie@stanford.edu., Zhu DY; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Lu Y; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA; Basic Sciences and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, CA, USA; Department of Computer Science, Stanford University, Stanford, CA 94305, USA; Electronic Information School, Wuhan University, Wuhan 430072, China., Yao J; BGI Research, Hangzhou 310030, China; BGI Research, Sanya 572025, China; College of Life Sciences, Northwest University, Xi'an 710069, China., Jing Z; BGI Research, Hangzhou 310030, China; BGI Research, Sanya 572025, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China., Min KH; Ginkgo Bioworks, The Innovation and Design Building, Boston, MA 02210, USA., Cheng M; BGI Research, Hangzhou 310030, China; BGI Research, Shenzhen 518083, China., Pan H; BGI Research, Shenzhen 518083, China., Zuo L; BGI Research, Shenzhen 518083, China., King S; Department of Bioengineering, Stanford University School of Medicine, Stanford, CA, USA., Fang Q; BGI Research, Hangzhou 310030, China; BGI Research, Shenzhen 518083, China., Zheng H; BGI Research, Hangzhou 310030, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China., Wang M; BGI Research, Hangzhou 310030, China; Shenzhen Key Laboratory of Gene Regulation and Systems Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China., Wang S; BGI Research, Hangzhou 310030, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China., Zhang Q; Department of Medicine, Division of Cardiology, University of California, San Diego, La Jolla, CA, USA., Yu S; Whitehead Institute for Biomedical Research, Cambridge, MA, USA., Liao S; BGI Research, Shenzhen 518083, China; STOmics Tech Co., Ltd, Shenzhen 518083, China; BGI Research, Chongqing 401329, China., Liu C; BGI Research, Wuhan 430074, China., Wu X; BGI Research, Hangzhou 310030, China; BGI Research, Sanya 572025, China; School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China., Lai Y; BGI Research, Shenzhen 518083, China., Hao S; BGI Research, Hangzhou 310030, China., Zhang Z; BGI Research, Hangzhou 310030, China; BGI Research, Sanya 572025, China; School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China., Wu L; BGI Research, Chongqing 401329, China., Zhang Y; BGI Research, Wuhan 430074, China., Li M; STOmics Tech Co., Ltd, Shenzhen 518083, China., Tu Z; BGI Research, Hangzhou 310030, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China., Lin J; BGI Research, Hangzhou 310030, China; BGI Research, Sanya 572025, China., Yang Z; BGI Research, Hangzhou 310030, China; School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China., Li Y; BGI Research, Wuhan 430074, China., Gu Y; BGI Research, Hangzhou 310030, China; BGI Research, Shenzhen 518083, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China., Ellison D; Infrastructure Solution Group, Lenovo., Chen A; BGI Research, Shenzhen 518083, China; STOmics Tech Co., Ltd, Shenzhen 518083, China; BGI Research, Chongqing 401329, China., Liu L; BGI Research, Hangzhou 310030, China; Shenzhen Bay Laboratory, Shenzhen 518132, China; Shenzhen Key Laboratory of Single-Cell Omics, BGI-Shenzhen, Shenzhen 518120, China., Weissman JS; Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA; Koch Institute for Integrative Cancer Research at MIT, MIT, Cambridge, MA, USA., Ma J; Electronic Information School, Wuhan University, Wuhan 430072, China. Electronic address: jyma2010@gmail.com., Xu X; BGI Research, Hangzhou 310030, China; College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China; Guangdong Provincial Key Laboratory of Genome Read and Write, BGI-Shenzhen, Shenzhen 518120, China. Electronic address: xuxun@genomics.cn., Liu S; BGI Research, Hangzhou 310030, China; Shenzhen Bay Laboratory, Shenzhen 518132, China; Shenzhen Key Laboratory of Single-Cell Omics, BGI-Shenzhen, Shenzhen 518120, China; The Guangdong-Hong Kong Joint Laboratory on Immunological and Genetic Kidney Diseases, Guangzhou, Guangdong, China. Electronic address: liushiping@genomics.cn., Bai Y; BGI Research, Sanya 572025, China; Hainan Technology Innovation Center for Marine Biological Resources Utilization (Preparatory Period), BGI Research, Sanya 572025, China. Electronic address: baiyinqi@genomics.com.

Publikováno v: Cell [Cell] 2024 Nov 11. Date of Electronic Publication: 2024 Nov 11.

The landscape of coding RNA editing events in pediatric cancer.

Autor: Wen J; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Rusch M; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Brady SW; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Shao Y; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Edmonson MN; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Shaw TI; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Powers BB; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Tian L; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Easton J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Mullighan CG; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Gruber T; Department of Pediatrics, Stanford University, Palo Alto, California, 94305, USA., Ellison D; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Zhang J; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA. Jinghui.Zhang@StJude.org.

Publikováno v: BMC cancer [BMC Cancer] 2021 Nov 17; Vol. 21 (1), pp. 1233. Date of Electronic Publication: 2021 Nov 17.