Zobrazeno 1 - 10
of 199
pro vyhledávání: '"David D. Eisenstat"'
Autor:
Claudia Toro, Ben Felmingham, Mangesh Jhadav, David S. Celermajer, Andre La Gerche, John O’Sullivan, Sanjeev Kumar, Marion K. Mateos, Joy Fulbright, Dinisha Govender, Lane Collier, Michael Cheung, David D. Eisenstat, Peter W. Lange, Julian Ayer, David A. Elliott, Rachel Conyers
Publikováno v:
Cardio-Oncology, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Background Modern oncological therapies together with chemotherapy and radiotherapy have broadened the agents that can cause cardiac sequelae, which can manifest for pediatric oncology patients while on active treatment. Recommendations for
Externí odkaz:
https://doaj.org/article/5416796c714c4b7ba15e1de7027ef7dd
Autor:
Jiesi Zhou, Yan Shu Kong, Krista M. Vincent, Dylan Dieters‐Castator, Amirali B. Bukhari, Darryl Glubrecht, Rong‐Zong Liu, Douglas Quilty, Scott D. Findlay, Xiaowei Huang, Zhihua Xu, Rui Zhe Yang, Lanyue Zhang, Emily Tang, Gilles Lajoie, David D. Eisenstat, Armin M. Gamper, Richard Fahlman, Roseline Godbout, Lynne‐Marie Postovit, YangXin Fu
Publikováno v:
Molecular Oncology, Vol 17, Iss 9, Pp 1763-1783 (2023)
Glioblastoma (GBM) is the most common and aggressive malignant primary brain tumor in adults. The standard treatment achieves a median overall survival for GBM patients of only 15 months. Hence, novel therapies based on an increased understanding of
Externí odkaz:
https://doaj.org/article/919b27202fed43f09567395980a0f763
Autor:
Liam M. Furst, Enola M. Roussel, Ryan F. Leung, Ankita M. George, Sarah A. Best, James R. Whittle, Ron Firestein, Maree C. Faux, David D. Eisenstat
Publikováno v:
Biology, Vol 13, Iss 6, p 424 (2024)
Pediatric high-grade gliomas (pHGG) are malignant and usually fatal central nervous system (CNS) WHO Grade 4 tumors. The majority of pHGG consist of diffuse midline gliomas (DMG), H3.3 or H3.1 K27 altered, or diffuse hemispheric gliomas (DHG) (H3.3 G
Externí odkaz:
https://doaj.org/article/20795f976df9419d8a9dc23c5ce09411
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 466-481 (2023)
The tumor suppressor p53 plays a critical role in cancer pathogenesis, and regulation of p53 expression is essential for maintaining normal cell growth. UBE4B is an E3/E4 ubiquitin ligase involved in a negative-feedback loop with p53. UBE4B is requir
Externí odkaz:
https://doaj.org/article/f673e8c9713c4e7889760607cba92ada
Autor:
Erik P. Sulman, David D. Eisenstat
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/c08250dde64f42e1977e2f2be79562f2
Autor:
Sarah M. Trinder, Campbell McKay, Phoebe Power, Monique Topp, Bosco Chan, Santosh Valvi, Geoffrey McCowage, Dinisha Govender, Maria Kirby, David S. Ziegler, Neevika Manoharan, Tim Hassall, Stewart Kellie, John Heath, Frank Alvaro, Paul Wood, Stephen Laughton, Karen Tsui, Andrew Dodgshun, David D. Eisenstat, Raelene Endersby, Stephen J. Luen, Eng-Siew Koh, Hao-Wen Sim, Benjamin Kong, Nicholas G. Gottardo, James R. Whittle, Dong-Anh Khuong-Quang, Jordan R. Hansford
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The mitogen-activated protein kinase (MAPK) pathway signaling pathway is one of the most commonly mutated pathways in human cancers. In particular, BRAF alterations result in constitutive activation of the rapidly accelerating fibrosarcoma–extracel
Externí odkaz:
https://doaj.org/article/b70dc0b5bc9c4f5f8e61a5acca858e20
Autor:
Benfan Wang, H. Helena Wu, Yasser Abuetabh, Sarah Leng, Sandra T. Davidge, Elsa R. Flores, David D. Eisenstat, Roger Leng
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-14 (2022)
Abstract As a key component of the RNA-induced silencing complex (RISC), Argonaute2 (Ago2) exhibits a dual function regulatory role in tumor progression. However, the mechanistic basis of differential regulation remains elusive. p63 is a homolog of t
Externí odkaz:
https://doaj.org/article/3d620a5bbcf14b43ac33f862bfab5f7f
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/5d3c4945450942629902ea27080afc3d
Autor:
Erik P. Sulman, David D. Eisenstat
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/d19c17773ee34e9f92cd1c16d3a3835b
Publikováno v:
BMC Health Services Research, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Patients in Alberta, Canada are referred to the United States (US) for proton treatment. The Alberta Ministry of Health pays for the proton treatment and the cost of flights to and from the United States. This study aimed to deter
Externí odkaz:
https://doaj.org/article/935b814ed3064dbf86b1efa1ba820a28