Zobrazeno 1 - 10
of 204
pro vyhledávání: '"David D Ward"'
Autor:
Lindsay M. K. Wallace, Olga Theou, Judith Godin, David D. Ward, Melissa K. Andrew, David A. Bennett, Kenneth Rockwood
Publikováno v:
Aging Medicine, Vol 4, Iss 4, Pp 250-256 (2021)
Abstract Main Problem Frailty is an established risk factor for cognitive decline and Alzheimer's disease. Few studies have examined the longitudinal relationship between frailty and cognition. Methods Participants of Rush Memory and Aging project (n
Externí odkaz:
https://doaj.org/article/5cae77940028482f853071d2ec381531
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Magnetic resonance imaging (MRI) offers significant insight into the complex organization of neural networks within the human brain. Using resting-state functional MRI data, topological maps can be created to visualize changes in brain activity, as w
Externí odkaz:
https://doaj.org/article/54987ebe9d934af989e00f826aee9bd0
Publikováno v:
Brain Sciences, Vol 10, Iss 4, p 195 (2020)
Brain-derived neurotropic factor (BDNF) is an abundant and multi-function neurotrophin in the brain. It is released following neuronal activity and is believed to be particularly important in strengthening neural networks. A common variation in the B
Externí odkaz:
https://doaj.org/article/b6396492173548a9b676a2a231e83c0a
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 93:343-350
ObjectiveTo optimise dementia prevention strategies, we must understand the complex relationships between lifestyle behaviours, frailty and genetics.MethodsWe explored relationships between frailty index, healthy lifestyle and polygenic risk scores (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9885323c53087c470b7877f7de46f9b
https://doi.org/10.1136/jnnp-2021-327396
https://doi.org/10.1136/jnnp-2021-327396
Autor:
Ravi Bhat, David D. Ward
Publikováno v:
International Psychogeriatrics. 33:755-757
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866b6c2fba720a27c71e47613479e120
https://doi.org/10.1017/s1041610220003968
https://doi.org/10.1017/s1041610220003968
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 92:136-142
ObjectiveTo determine whether health-deficit accumulation is associated with the risks of mild cognitive impairment (MCI) and dementia independently of APOE genotype.MethodsA frailty index was calculated using the deficit-accumulation approach in par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::715477d3868d92d065181070d44818b6
https://doi.org/10.1136/jnnp-2020-324081
https://doi.org/10.1136/jnnp-2020-324081
Autor:
Robert P. Finger, Natascha Merten, Monique M.B. Breteler, Meta M. Bönniger, David D. Ward, Matthias M. Mauschitz
Publikováno v:
Neurology. 95:e1144-e1152
ObjectiveTo quantify the associations of peripapillary retinal nerve fiber layer (pRNFL) thickness and macular ganglion cell layer (mGCL) volume with cognitive functioning and to investigate how demographic and vascular health factors affect these as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0df893611bfe9313a68b469b7becfd2
https://doi.org/10.1212/wnl.0000000000010146
https://doi.org/10.1212/wnl.0000000000010146
Autor:
Andrew Robinson, Mathew J. Summers, Velandai Srikanth, Karen Ritchie, Michael Valenzuela, Jeffery J. Summers, James C. Vickers, David D. Ward, Anna E. King
Publikováno v:
The Journal of Prevention of Alzheimer's Disease. :1-6
In 358 participants of the Tasmanian Healthy Brain Project, we quantified the cognitive consequences of engaging in varying loads of university-level education in later life, and investigated whether or not BDNF Val66Met affected outcomes. Assessment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4d26b532705cffc892e60e4102ec14
https://doi.org/10.14283/jpad.2019.40
https://doi.org/10.14283/jpad.2019.40
Publikováno v:
Annals of neurologyReferences. 89(6)
Risk factors for developing dementia from mild cognitive impairment (MCI) probably differ between MCI subtypes. We investigated how frailty relates to dementia risk in amnestic MCI (a-MCI; n = 2,799) and non-amnestic MCI (na-MCI; n = 629) in the Nati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9974350c4969577322966e59a24915
https://pubmed.ncbi.nlm.nih.gov/33866586
https://pubmed.ncbi.nlm.nih.gov/33866586
Autor:
Ulrich Ettinger, Natascha Merten, Matthias Schmid, Monique M.B. Breteler, David D. Ward, Annabell Coors
Publikováno v:
Vision research 178, 124-133 (2021). doi:10.1016/j.visres.2020.10.004
Assessing physiological changes that occur with healthy ageing is prerequisite for understanding pathophysiological age-related changes. Eye movements are studied as biomarkers for pathological changes because they are altered in patients with neurod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7e15264f956eeb578bde93d94c58c7f
https://pub.dzne.de/record/155678
https://pub.dzne.de/record/155678
