Critical role of macrophages and their activation via MyD88-NFκB signaling in lung innate immunity to Mycoplasma pneumoniae.

Autor: Jen-Feng Lai, Carlene L Zindl, Lynn B Duffy, T Prescott Atkinson, Yong Woo Jung, Nico van Rooijen, Ken B Waites, Duncan C Krause, David D Chaplin

Publikováno v: PLoS ONE, Vol 5, Iss 12, p e14417 (2010)

Mycoplasma pneumoniae (Mp), a common cause of pneumonia, is associated with asthma; however, the mechanisms underlying this association remain unclear. We investigated the cellular immune response to Mp in mice. Intranasal inoculation with Mp elicite

Externí odkaz: https://doaj.org/article/03cff92743aa40d28504c5fac909abc3

Distal airway microbiome is associated with immunoregulatory myeloid cell responses in lung transplant recipients

Autor: David D. Chaplin, Ritesh K. Srivastava, Charles W. Hoopes, Kui Zhang, Kenneth P. Hough, Yong Wang, Jessy S. Deshane, Ranjit Kumar, Keith M. Wille, Nirmal S. Sharma, Jose Rodriguez Dager, Mohammad Athar, Casey D. Morrow, S. Athira, Sunad Rangarajan, Enrique Diaz-Guzman, Victor J. Thannickal, Degui Zhi, Peter Eipers

Publikováno v: The Journal of Heart and Lung Transplantation. 37:206-216

Background Long-term survival of lung transplant recipients (LTRs) is limited by the occurrence of bronchiolitis obliterans syndrome (BOS). Recent evidence suggests a role for microbiome alterations in the occurrence of BOS, although the precise mech

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e24decfd6220e8626f33566f2ad68c
https://doi.org/10.1016/j.healun.2017.07.007

List of Contributors

Autor: Roshini Sarah Abraham, Cristina Albanesi, Ilias Alevizos, Juan Anguita, Brendan Antiochos, Cynthia Aranow, John P. Atkinson, Howard A. Austin, Subash Babu, Mark C. Ballow, James E. Balow, John W. Belmont, Claudia Berek, Timothy Beukelman, Tapan Bhavsar, J. Andrew Bird, Sarah E. Blutt, Mark Boguniewicz, Rafael Bonamichi-Santos, Bertrand Boisson, Elena Borzova, Prosper N. Boyaka, Joshua Boyce, Sarah K. Browne, Wesley Burks, Jacinta Bustamante, Virginia L. Calder, Matthew Campbell, Adela Rambi G. Cardones, Jean-Laurent Casanova, Mariana Castells, Lisa A. Cavacini, Edwin S.L. Chan, David D. Chaplin, W. Winn Chatham, Edward S. Chen, Javier Chinen, Lisa Christopher-Stine, Michael Ciancanelli, Andrew P. Cope, David B. Corry, Filippo Crea, Randy Q. Cron, Jennifer M. Cuellar-Rodriguez, Marinos C. Dalakas, Sara M. Dann, Betty Diamond, Terry W. Du, Stéphanie Dupuis-Boisson, Todd N. Eagar, Craig A. Elmets, Doruk Erkan, Laura Fanning, Erol Fikrig, Davide Flego, Thomas A. Fleisher, Luz Fonacier, Andrew P. Fontenot, Alexandra F. Freeman, Anthony J. Frew, Kohtaro Fujihashi, Massimo Gadina, Moshe E. Gatt, M. Eric Gershwin, Susan L. Gillespie, Jörg J. Goronzy, Sangeeta Goswami, Clive E.H. Grattan, Neil S. Greenspan, Sarthak Gupta, Claire E. Gustafson, Russell P. Hall, Robert G. Hamilton, Laurie E. Harrington, Leonard C. Harrison, Sarfaraz A. Hasni, Arthur Helbling, Joanna Hester, Steven M. Holland, Dennis Hourcade, Nicholas D. Huntington, Tracy Hwangpo, John B. Imboden, Fadi Issa, Shai Izraeli, Elaine S. Jaffe, Sirpa Jalkanen, Stacie Jones, Emmanuelle Jouanguy, Sarah Kabbani, Stefan H.E. Kaufmann, Farrah Kheradmand, Donald B. Kohn, Robert Korngold, Anna Kovalszki, Douglas B. Kuhns, Hrishikesh Kulkarni, Caroline Y. Kuo, Arash Lahouti, C. Ola Landgren, Arian Laurence, Joyce S. Lee, Catherine Lemière, Donald Y.M. Leung, Arnold I. Levinson, Ofer Levy, Dorothy E. Lewis, Phoebe Lin, Andreas Linkermann, Giovanna Liuzzo, Michael D. Lockshin, Allison K. Lord, Jay N. Lozier, Amber Luong, Raashid Luqmani, Meggan Mackay, Jonathan S. Maltzman, Peter J. Mannon, Michael P. Manns, James G. Martin, Craig L. Maynard, Samual McCash, Douglas R. McDonald, Peter C. Melby, Stephen D. Miller, Anna L. Mitchell, Amirah Mohd-Zaki, Carolyn Mold, David R. Moller, Dimitrios S. Monos, Scott N. Mueller, Catharina M. Mulders-Manders, Mark J. Mulligan, Ulrich R. Müller, Pashna N. Munshi, Kazunori Murata, Philip M. Murphy, Nicolás Navasa, Pierre Noel, Luigi D. Notarangelo, Robert L. Nussbaum, Thomas B. Nutman, Stephen L. Nutt, João B. Oliveira, Thomas L. Ortel, John J. O'Shea, Sung-Yun Pai, Lavannya Pandit, Mary E. Paul, Simon H.S. Pearce, Daniela Pedicino, Erik J. Peterson, Capucine Picard, Stefania Pittaluga, Debra Long Priel, Jennifer Puck, Anne Puel, Andreas Radbruch, Stephen T. Reece, John D. Reveille, Robert R. Rich, Chaim M. Roifman, Antony Rosen, James T. Rosenbaum, Sergio D. Rosenzweig, Barry T. Rouse, Scott D. Rowley, Shimon Sakaguchi, Marko Salmi, Andrea J. Sant, Sarah W. Satola, Valerie Saw, Marcos C. Schechter, Harry W. Schroeder, Benjamin M. Segal, Carlo Selmi, Sushma Shankar, Anu Sharma, Padmanee Sharma, William T. Shearer, Richard M. Siegel, Anna Simon, Gideon P. Smith, David S. Stephens, Robin Stephens, Alex Straumann, Leyla Y. Teos, Laura Timares, Wulf Tonnus, Raul M. Torres, Gülbü Uzel, Jeroen C.H. van der Hilst, Jos W.M. van der Meer, John Varga, Jatin M. Vyas, Meryl Waldman, Peter Weiser, Peter F. Weller, Cornelia M. Weyand, Fredrick M. Wigley, Robert J. Winchester, James B. Wing, Kathryn J. Wood, Xiaobo Wu, Hui Xu, Cassian Yee, Shen-Ying Zhang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3e8530ab74166b9db30151eb919887f
https://doi.org/10.1016/b978-0-7020-6896-6.00104-6

IL-1β in eosinophil-mediated small intestinal homeostasis and IgA production

Autor: Ting Wen, Y H Wang, Myoung Ho Jang, E H Lee, Yun-Jae Jung, Marc E. Rothenberg, Ju Young Seoh, M K Mingler, So Youn Woo, J M Caldwell, Masayuki Miyasaka, David D. Chaplin

Publikováno v: Mucosal immunology

Eosinophils are multifunctional leukocytes that reside in the gastrointestinal (GI) lamina propria, where their basal function remains largely unexplored. In this study, by examining mice with a selective deficiency of systemic eosinophils (by lineag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b51a7369d861741ea1676d2698cce0b
https://doi.org/10.1038/mi.2014.123

AMP‐activated protein kinase enhances the phagocytic ability of macrophages and neutrophils

Autor: Jean-Marc Tadié, Jessy S. Deshane, Seiji Takashima, Jaroslaw W. Zmijewski, David D. Chaplin, Edward Abraham, Hong-Beom Bae

Publikováno v: The FASEB Journal. 25:4358-4368

Although AMPK plays well-established roles in the modulation of energy balance, recent studies have shown that AMPK activation has potent anti-inflammatory effects. In the present experiments, we examined the role of AMPK in phagocytosis. We found th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab41e5fde5131fc8c58d02f9ad29f63e
https://doi.org/10.1096/fj.11-190587