Zobrazeno 1 - 10
of 146
pro vyhledávání: '"David D Bowtell"'
Autor:
Martin Köbel, Eun‐Young Kang, Ashley Weir, Peter F Rambau, Cheng‐Han Lee, Gregg S Nelson, Prafull Ghatage, Nicola S Meagher, Marjorie J Riggan, Jennifer Alsop, Michael S Anglesio, Matthias W Beckmann, Christiani Bisinotto, Michelle Boisen, Jessica Boros, Alison H Brand, Angela Brooks‐Wilson, Michael E Carney, Penny Coulson, Madeleine Courtney‐Brooks, Kara L Cushing‐Haugen, Cezary Cybulski, Suha Deen, Mona A El‐Bahrawy, Esther Elishaev, Ramona Erber, Sian Fereday, AOCS Group, Anna Fischer, Simon A Gayther, Arantzazu Barquin‐Garcia, Aleksandra Gentry‐Maharaj, C Blake Gilks, Helena Gronwald, Marcel Grube, Paul R Harnett, Holly R Harris, Andreas D Hartkopf, Arndt Hartmann, Alexander Hein, Joy Hendley, Brenda Y Hernandez, Yajue Huang, Anna Jakubowska, Mercedes Jimenez‐Linan, Michael E Jones, Catherine J Kennedy, Tomasz Kluz, Jennifer M Koziak, Jaime Lesnock, Jenny Lester, Jan Lubiński, Teri A Longacre, Maria Lycke, Constantina Mateoiu, Bryan M McCauley, Valerie McGuire, Britta Ney, Alexander Olawaiye, Sandra Orsulic, Ana Osorio, Luis Paz‐Ares, Teresa Ramón y Cajal, Joseph H Rothstein, Matthias Ruebner, Minouk J Schoemaker, Mitul Shah, Raghwa Sharma, Mark E Sherman, Yurii B Shvetsov, Naveena Singh, Helen Steed, Sarah J Storr, Aline Talhouk, Nadia Traficante, Chen Wang, Alice S Whittemore, Martin Widschwendter, Lynne R Wilkens, Stacey J Winham, Javier Benitez, Andrew Berchuck, David D Bowtell, Francisco J Candido dos Reis, Ian Campbell, Linda S Cook, Anna DeFazio, Jennifer A Doherty, Peter A Fasching, Renée T Fortner, María J García, Marc T Goodman, Ellen L Goode, Jacek Gronwald, David G Huntsman, Beth Y Karlan, Linda E Kelemen, Stefan Kommoss, Nhu D Le, Stewart G Martin, Usha Menon, Francesmary Modugno, Paul DP Pharoah, Joellen M Schildkraut, Weiva Sieh, Annette Staebler, Karin Sundfeldt, Anthony J Swerdlow, Susan J Ramus, James D Brenton
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 3, Pp 208-222 (2023)
Abstract Our objective was to test whether p53 expression status is associated with survival for women diagnosed with the most common ovarian carcinoma histotypes (high‐grade serous carcinoma [HGSC], endometrioid carcinoma [EC], and clear cell carc
Externí odkaz:
https://doaj.org/article/493c5874781345c8971b7e798d52a02b
Autor:
Peter Savas, Zhi Ling Teo, Christophe Lefevre, Christoffer Flensburg, Franco Caramia, Kathryn Alsop, Mariam Mansour, Prudence A Francis, Heather A Thorne, Maria Joao Silva, Nnennaya Kanu, Michelle Dietzen, Andrew Rowan, Maik Kschischo, Stephen Fox, David D Bowtell, Sarah-Jane Dawson, Terence P Speed, Charles Swanton, Sherene Loi
Publikováno v:
PLoS Medicine, Vol 14, Iss 4, p e1002302 (2017)
[This corrects the article DOI: 10.1371/journal.pmed.1002204.].
Externí odkaz:
https://doaj.org/article/cafa5e89f98445938643c1e55091070d
Autor:
Peter Savas, Zhi Ling Teo, Christophe Lefevre, Christoffer Flensburg, Franco Caramia, Kathryn Alsop, Mariam Mansour, Prudence A Francis, Heather A Thorne, Maria Joao Silva, Nnennaya Kanu, Michelle Dietzen, Andrew Rowan, Maik Kschischo, Stephen Fox, David D Bowtell, Sarah-Jane Dawson, Terence P Speed, Charles Swanton, Sherene Loi
Publikováno v:
PLoS Medicine, Vol 13, Iss 12, p e1002204 (2016)
BackgroundUnderstanding the cancer genome is seen as a key step in improving outcomes for cancer patients. Genomic assays are emerging as a possible avenue to personalised medicine in breast cancer. However, evolution of the cancer genome during the
Externí odkaz:
https://doaj.org/article/845b0b97cdff4b488f9f2ce3d5e69381
Autor:
Eun-Young, Kang, Ashley, Weir, Nicola S, Meagher, Kyo, Farrington, Gregg S, Nelson, Prafull, Ghatage, Cheng-Han, Lee, Marjorie J, Riggan, Adelyn, Bolithon, Gordana, Popovic, Betty, Leung, Katrina, Tang, Neil, Lambie, Joshua, Millstein, Jennifer, Alsop, Michael S, Anglesio, Beyhan, Ataseven, Ellen, Barlow, Matthias W, Beckmann, Jessica, Berger, Christiani, Bisinotto, Hans, Bösmüller, Jessica, Boros, Alison H, Brand, Angela, Brooks-Wilson, Sara Y, Brucker, Michael E, Carney, Yovanni, Casablanca, Alicia, Cazorla-Jiménez, Paul A, Cohen, Thomas P, Conrads, Linda S, Cook, Penny, Coulson, Madeleine, Courtney-Brooks, Daniel W, Cramer, Philip, Crowe, Julie M, Cunningham, Cezary, Cybulski, Kathleen M, Darcy, Mona A, El-Bahrawy, Esther, Elishaev, Ramona, Erber, Rhonda, Farrell, Sian, Fereday, Anna, Fischer, María J, García, Simon A, Gayther, Aleksandra, Gentry-Maharaj, C Blake, Gilks, Marcel, Grube, Paul R, Harnett, Shariska Petersen, Harrington, Philipp, Harter, Arndt, Hartmann, Jonathan L, Hecht, Sebastian, Heikaus, Alexander, Hein, Florian, Heitz, Joy, Hendley, Brenda Y, Hernandez, Susanna Hernando, Polo, Sabine, Heublein, Akira, Hirasawa, Estrid, Høgdall, Claus K, Høgdall, Hugo M, Horlings, David G, Huntsman, Tomasz, Huzarski, Andrea, Jewell, Mercedes, Jimenez-Linan, Michael E, Jones, Scott H, Kaufmann, Catherine J, Kennedy, Dineo, Khabele, Felix K F, Kommoss, Roy F P M, Kruitwagen, Diether, Lambrechts, Nhu D, Le, Marcin, Lener, Jenny, Lester, Yee, Leung, Anna, Linder, Liselore, Loverix, Jan, Lubiński, Rashna, Madan, G Larry, Maxwell, Francesmary, Modugno, Susan L, Neuhausen, Alexander, Olawaiye, Siel, Olbrecht, Sandra, Orsulic, José, Palacios, Celeste Leigh, Pearce, Malcolm C, Pike, Carmel M, Quinn, Ganendra Raj, Mohan, Cristina, Rodríguez-Antona, Matthias, Ruebner, Andy, Ryan, Stuart G, Salfinger, Naoko, Sasamoto, Joellen M, Schildkraut, Minouk J, Schoemaker, Mitul, Shah, Raghwa, Sharma, Yurii B, Shvetsov, Naveena, Singh, Gabe S, Sonke, Linda, Steele, Colin J R, Stewart, Karin, Sundfeldt, Anthony J, Swerdlow, Aline, Talhouk, Adeline, Tan, Sarah E, Taylor, Kathryn L, Terry, Aleksandra, Tołoczko, Nadia, Traficante, Koen K, Van de Vijver, Maaike A, van der Aa, Toon, Van Gorp, Els, Van Nieuwenhuysen, Lilian, van-Wagensveld, Ignace, Vergote, Robert A, Vierkant, Chen, Wang, Lynne R, Wilkens, Stacey J, Winham, Anna H, Wu, Javier, Benitez, Andrew, Berchuck, Francisco J, Candido Dos Reis, Anna, DeFazio, Peter A, Fasching, Ellen L, Goode, Marc T, Goodman, Jacek, Gronwald, Beth Y, Karlan, Stefan, Kommoss, Usha, Menon, Hans-Peter, Sinn, Annette, Staebler, James D, Brenton, David D, Bowtell, Paul D P, Pharoah, Susan J, Ramus, Martin, Köbel
Publikováno v:
Cancer, 129(5), 697-713. Wiley
Cancer: interdisciplinary international journal of the American Cancer Society
Cancer: interdisciplinary international journal of the American Cancer Society
BACKGROUND: Cyclin E1 (CCNE1) is a potential predictive marker and therapeutic target in tubo-ovarian high-grade serous carcinoma (HGSC). Smaller studies have revealed unfavorable associations for CCNE1 amplification and CCNE1 overexpression with sur
Autor:
Ashley, Weir, Eun-Young, Kang, Nicola S, Meagher, Gregg S, Nelson, Prafull, Ghatage, Cheng-Han, Lee, Marjorie J, Riggan, Aleksandra, Gentry-Maharaj, Andy, Ryan, Naveena, Singh, Martin, Widschwendter, Jennifer, Alsop, Michael S, Anglesio, Matthias W, Beckmann, Jessica, Berger, Christiani, Bisinotto, Jessica, Boros, Alison H, Brand, James D, Brenton, Angela, Brooks-Wilson, Michael E, Carney, Julie M, Cunningham, Kara L, Cushing-Haugen, Cezary, Cybulski, Esther, Elishaev, Ramona, Erber, Sian, Fereday, Anna, Fischer, Luis, Paz-Ares, Javier, Gayarre, Blake C, Gilks, Marcel, Grube, Paul R, Harnett, Holly R, Harris, Arndt, Hartmann, Alexander, Hein, Joy, Hendley, Brenda Y, Hernandez, Sabine, Heublein, Yajue, Huang, Tomasz, Huzarski, Anna, Jakubowska, Mercedes, Jimenez-Linan, Catherine J, Kennedy, Felix K F, Kommoss, Jennifer M, Koziak, Bernhard, Kraemer, Nhu D, Le, Jaime, Lesnock, Jenny, Lester, Jan, Lubiński, Janusz, Menkiszak, Britta, Ney, Alexander, Olawaiye, Sandra, Orsulic, Ana, Osorio, Luis, Robles-Díaz, Matthias, Ruebner, Mitul, Shah, Raghwa, Sharma, Yurii B, Shvetsov, Helen, Steed, Aline, Talhouk, Sarah E, Taylor, Nadia, Traficante, Robert A, Vierkant, Chen, Wang, Lynne R, Wilkens, Stacey J, Winham, Javier, Benitez, Andrew, Berchuck, David D, Bowtell, Francisco J, Candido Dos Reis, Linda S, Cook, Anna, DeFazio, Jennifer A, Doherty, Peter A, Fasching, María J, García, Ellen L, Goode, Marc T, Goodman, Jacek, Gronwald, David G, Huntsman, Beth Y, Karlan, Stefan, Kommoss, Francesmary, Modugno, Joellen M, Schildkraut, Hans-Peter, Sinn, Annette, Staebler, Linda E, Kelemen, Caroline E, Ford, Usha, Menon, Paul D P, Pharoah, Martin, Köbel, R, Sharma
Publikováno v:
British Journal of Cancer. 128:137-147
Background Recently, we showed a >60% difference in 5-year survival for patients with tubo-ovarian high-grade serous carcinoma (HGSC) when stratified by a 101-gene mRNA expression prognostic signature. Given the varied patient outcomes, this study ai
Autor:
Gwo Yaw, Ho, Elizabeth L, Kyran, Justin, Bedo, Matthew J, Wakefield, Darren P, Ennis, Hasan B, Mirza, Cassandra J, Vandenberg, Elizabeth, Lieschke, Andrew, Farrell, Anthony, Hadla, Ratana, Lim, Genevieve, Dall, James E, Vince, Ngee Kiat, Chua, Olga, Kondrashova, Rosanna, Upstill-Goddard, Ulla-Maja, Bailey, Suzanne, Dowson, Patricia, Roxburgh, Rosalind M, Glasspool, Gareth, Bryson, Andrew V, Biankin, Susanna L, Cooke, Gayanie, Ratnayake, Orla, McNally, Nadia, Traficante, Anna, DeFazio, S John, Weroha, David D, Bowtell, Iain A, McNeish, Anthony T, Papenfuss, Clare L, Scott, Holly E, Barker
Publikováno v:
Cancer Research. 82:4457-4473
Ovarian carcinosarcoma (OCS) is an aggressive and rare tumor type with limited treatment options. OCS is hypothesized to develop via the combination theory, with a single progenitor resulting in carcinomatous and sarcomatous components, or alternativ
Autor:
Frances R. Balkwill, Eleni Maniati, Jacqueline McDermott, David D. Bowtell, Rebecca Kristeleit, Dale W. Garsed, Panoraia Kotantaki, Florian Laforets, Rowan Miller, Michael-John Devlin
Some patients with advanced clear-cell ovarian cancer (CCOC) respond to immunotherapy; however, little is known about the tumor microenvironment (TME) of this relatively rare disease. Here, we describe a comprehensive quantitative and topographical a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52749b1e5bf69beb0cbaba8b638c10e4
https://doi.org/10.1158/2326-6066.c.6550844
https://doi.org/10.1158/2326-6066.c.6550844
Autor:
Frances R. Balkwill, Eleni Maniati, Jacqueline McDermott, David D. Bowtell, Rebecca Kristeleit, Dale W. Garsed, Panoraia Kotantaki, Florian Laforets, Rowan Miller, Michael-John Devlin
Supplementary Data from The Tumor Microenvironment of Clear-Cell Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e61a7ba2340c61b7783fccf4a4e1559
https://doi.org/10.1158/2326-6066.22545056.v1
https://doi.org/10.1158/2326-6066.22545056.v1
Autor:
Ellen L. Goode, Stacey J. Winham, David D. Bowtell, Jesus Gonzalez Bosquet, Tanja Pejovic, Martin Widschwendter, Michael S. Anglesio, Dinuka Ariyaratne, Jennifer A. Doherty, Sian Fereday, Dale W. Garsed, Brooke D. Jorgensen, Martin Köbel, Nadja Pejovic, Susan J. Ramus, Aline Talhouk, Nadia Traficante, Robert A. Vierkant, Sebastian M. Armasu, Bryan M. McCauley, Mark E. Sherman, Julie M. Cunningham, Matthew S. Block, Chen Wang
Supplementary Figure 4: Correlations between Methylation at CpG Sites and TAP1 mRNA Expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2430ad7223d7ccda62b7ebdea698ae9b
https://doi.org/10.1158/1055-9965.22494867
https://doi.org/10.1158/1055-9965.22494867
Autor:
Ellen L. Goode, Stacey J. Winham, David D. Bowtell, Jesus Gonzalez Bosquet, Tanja Pejovic, Martin Widschwendter, Michael S. Anglesio, Dinuka Ariyaratne, Jennifer A. Doherty, Sian Fereday, Dale W. Garsed, Brooke D. Jorgensen, Martin Köbel, Nadja Pejovic, Susan J. Ramus, Aline Talhouk, Nadia Traficante, Robert A. Vierkant, Sebastian M. Armasu, Bryan M. McCauley, Mark E. Sherman, Julie M. Cunningham, Matthew S. Block, Chen Wang
Supplementary Figure 1: Methylation Signature Approximation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142de5e90288c112b042e3e035d61f7f
https://doi.org/10.1158/1055-9965.22494876.v1
https://doi.org/10.1158/1055-9965.22494876.v1