Zobrazeno 1 - 10
of 334
pro vyhledávání: '"David D, Limbrick"'
Autor:
Maria Garcia-Bonilla, Alexander T. Yahanda, Albert M. Isaacs, Brandon Baksh, S. Hassan A. Akbari, Haley Botteron, Diego M. Morales, Rowland H. Han, James P. McAllister II, Amit M. Mathur, Jennifer M. Strahle, Christopher D. Smyser, David D. Limbrick
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-10 (2024)
Abstract Background Interpretation of cerebrospinal fluid (CSF) studies can be challenging in preterm infants. We hypothesized that intraventricular hemorrhage (IVH), post-hemorrhagic hydrocephalus (PHH), and infection (meningitis) promote pro-inflam
Externí odkaz:
https://doaj.org/article/db8823da1aa249aeb704a85931e70abc
Cognition and Brain System Segregation in Pediatric Brain Tumor Patients Treated with Proton Therapy
Autor:
Anna V. Dowling, BS, Benjamin A. Seitzman, PhD, Timothy J. Mitchell, PhD, Michael Olufawo, BS, Donna L. Dierker, BS, Hari Anandarajah, BS, Ally Dworetsky, BS, Alana McMichael, MA, Catherine Jiang, BS, Dennis L. Barbour, MD, PhD, Bradley L. Schlaggar, MD, PhD, David D. Limbrick, MD, PhD, Jennifer M. Strahle, MD, Joshua B. Rubin, MD, PhD, Joshua S. Shimony, MD, PhD, Stephanie M. Perkins, MD
Publikováno v:
International Journal of Particle Therapy, Vol 10, Iss 1, Pp 32-42 (2023)
Purpose: Pediatric brain tumor patients often experience significant cognitive sequelae. Resting-state functional MRI (rsfMRI) provides a measure of brain network organization, and we hypothesize that pediatric brain tumor patients treated with proto
Externí odkaz:
https://doaj.org/article/85b85912dbc44bb6a115be9892e779ca
Autor:
Jason K. Karimy, Jessie C. Newville, Cameron Sadegh, Jill A. Morris, Edwin S. Monuki, David D. Limbrick, James P. McAllister II, Jenna E. Koschnitzky, Maria K. Lehtinen, Lauren L. Jantzie
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract The Hydrocephalus Association (HA) workshop, Driving Common Pathways: Extending Insights from Posthemorrhagic Hydrocephalus, was held on November 4 and 5, 2019 at Washington University in St. Louis. The workshop brought together a diverse gr
Externí odkaz:
https://doaj.org/article/539642b289504d639e5e88ca53cd606e
Autor:
Fatemeh Khodadadei, Rooshan Arshad, Diego M. Morales, Jacob Gluski, Neena I. Marupudi, James P. McAllister, David D. Limbrick, Carolyn A. Harris
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-12 (2022)
Abstract Background The composition of tissue obstructing neuroprosthetic devices is largely composed of inflammatory cells with a significant astrocyte component. In a first-of-its-kind study, we profile the astrocyte phenotypes present on hydroceph
Externí odkaz:
https://doaj.org/article/9f1353d0baab43a9b75dc21054bdfc20
Autor:
Christopher E. Pope, Kathryn B. Whitlock, Paul Hodor, David D. Limbrick, Patrick J. McDonald, Jason Hauptman, Lucas R. Hoffman, Tamara D. Simon
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Advances in both laboratory and computational components of high-throughput 16S amplicon sequencing (16S HTS) have markedly increased its sensitivity and specificity. Additionally, these refinements have better delineated the limits of sensi
Externí odkaz:
https://doaj.org/article/cc7c1954506b4d81bf04ecd1719f38a1
Autor:
Maria Garcia-Bonilla, Leandro Castaneyra-Ruiz, Sarah Zwick, Michael Talcott, Ayodamola Otun, Albert M. Isaacs, Diego M. Morales, David D. Limbrick, James P. McAllister
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-18 (2022)
Abstract Background Hydrocephalus is a neurological disease with an incidence of 80–125 per 100,000 births in the United States. Neuropathology comprises ventriculomegaly, periventricular white matter (PVWM) alterations, inflammation, and gliosis.
Externí odkaz:
https://doaj.org/article/40f8f752c31d4c6b867f37cda1fa9bf4
Autor:
Shailly Pandey, Kathryn B. Whitlock, Matthew R. Test, Paul Hodor, Christopher E. Pope, David D. Limbrick, Patrick J. McDonald, Jason S. Hauptman, Lucas R. Hoffman, Tamara D. Simon
Publikováno v:
PLoS ONE, Vol 18, Iss 6 (2023)
Objective To characterize the microbiota of the cerebrospinal fluid (CSF) from children with hydrocephalus at the time of initial surgical intervention. Study design CSF was obtained at initial surgical intervention. One aliquot was stored in skim mi
Externí odkaz:
https://doaj.org/article/eee734ba8ea3434ea393f971399638d2
Autor:
Ayodamola Otun, Diego M. Morales, Maria Garcia-Bonilla, Seth Goldberg, Leandro Castaneyra-Ruiz, Yan Yan, Albert M. Isaacs, Jennifer M. Strahle, James P. McAllister, David D. Limbrick
Publikováno v:
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Background Intraventricular hemorrhage (IVH) and post-hemorrhagic hydrocephalus (PHH) have a complex pathophysiology involving inflammatory response, ventricular zone and cell–cell junction disruption, and choroid-plexus (ChP) hypersecreti
Externí odkaz:
https://doaj.org/article/855255a9132c440da6a306a4ef613b64
Autor:
James P. McAllister, Michael R. Talcott, Albert M. Isaacs, Sarah H. Zwick, Maria Garcia-Bonilla, Leandro Castaneyra-Ruiz, Alexis L. Hartman, Ryan N. Dilger, Stephen A. Fleming, Rebecca K. Golden, Diego M. Morales, Carolyn A. Harris, David D. Limbrick
Publikováno v:
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background Many animal models have been used to study the pathophysiology of hydrocephalus; most of these have been rodent models whose lissencephalic cerebral cortex may not respond to ventriculomegaly in the same way as gyrencephalic speci
Externí odkaz:
https://doaj.org/article/73f88d36430b4518b7d5660ba1adf8ef
Autor:
Christine Hehnly, Aiqin Shi, Paddy Ssentongo, Lijun Zhang, Albert Isaacs, Sarah U. Morton, Nicholas Streck, Petra Erdmann-Gilmore, Igor Tolstoy, R. Reid Townsend, David D. Limbrick, Joseph N. Paulson, Jessica E. Ericson, Michael Y. Galperin, Steven J. Schiff, James R. Broach
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Hydrocephalus, the leading indication for childhood neurosurgery worldwide, is particularly prevalent in low- and middle-income countries. Hydrocephalus preceded by an infection, or postinfectious hydrocephalus, accounts for up to 60% of hyd
Externí odkaz:
https://doaj.org/article/4ed3d517da8341ba9e490b66a1529316