Zobrazeno 1 - 10
of 516
pro vyhledávání: '"David D, Ho"'
Autor:
Michael S. Piepenbrink, Ahmed Magdy Khalil, Ana Chang, Ahmed Mostafa, Madhubanti Basu, Sanghita Sarkar, Simran Panjwani, Yaelyn H. Ha, Yao Ma, Chengjin Ye, Qian Wang, Todd J. Green, James L. Kizziah, Nathaniel B. Erdmann, Paul A. Goepfert, Lihong Liu, David D. Ho, Luis Martinez-Sobrido, Mark R. Walter, James J. Kobie
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-10 (2024)
Abstract SARS-CoV-2 continues to be a public health burden, driven in-part by its continued antigenic diversification and resulting emergence of new variants. By increasing herd immunity, current vaccines have improved infection outcomes for many. Ho
Externí odkaz:
https://doaj.org/article/fc93c8dbfeef47ec8f5ad7779811e16c
Autor:
Qian Wang, Ian A. Mellis, Jerren Ho, Anthony Bowen, Theresa Kowalski-Dobson, Riccardo Valdez, Phinikoula S. Katsamba, Madeline Wu, Caitlin Lee, Lawrence Shapiro, Aubree Gordon, Yicheng Guo, David D. Ho, Lihong Liu
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
The recently dominant SARS-CoV-2 Omicron JN.1 has evolved into multiple sublineages, with recurrent spike mutations R346T, F456L, and T572I, some of which exhibit growth advantages, such as KP.2 and KP.3. We investigated these mutations in JN.1, exam
Externí odkaz:
https://doaj.org/article/bc84833b02134f64ae87a0a39aa1751b
Autor:
Qian Wang, Yicheng Guo, Logan T. Schwanz, Ian A. Mellis, Yiwei Sun, Yiming Qu, Guillaume Urtecho, Riccardo Valdez, Emily Stoneman, Aubree Gordon, Harris H. Wang, David D. Ho, Lihong Liu
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
As SARS-CoV-2 continues to spread and mutate, tracking the viral evolutionary trajectory and understanding the functional consequences of its mutations remain crucial. Here, we characterized the antibody evasion, ACE2 receptor engagement, and viral i
Externí odkaz:
https://doaj.org/article/abf1d75ad25541d9b5a79451cfd5d018
Autor:
Manxue Jia, Hanjun Zhao, Nicholas C. Morano, Hong Lu, Yin-Ming Lui, Haijuan Du, Jordan E. Becker, Kwok-Yung Yuen, David D. Ho, Peter D. Kwong, Lawrence Shapiro, Kelvin Kai-Wang To, Xueling Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Avian influenza A virus H7N9 causes severe human infections with >30% fatality. Currently, there is no H7N9-specific prevention or treatment for humans. Here, from a 2013 H7N9 convalescent case in Hong Kong, we isolate four hemagglutinin (HA
Externí odkaz:
https://doaj.org/article/83d250f54cd64895b1f4e8c2f5942319
Autor:
Qian Wang, Ian A. Mellis, Yicheng Guo, Carmen Gherasim, Riccardo Valdez, Aubree Gordon, David D. Ho, Lihong Liu
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101701- (2024)
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing antibodies are substantially expanded 1 month after a shot of XBB.1.5 monovalent mRNA vaccine (XBB.1.5 MV) booster, but the durability of this response remains unknown
Externí odkaz:
https://doaj.org/article/f5b9cb0a4d4e4260850a9ce6c4be20f5
Autor:
Jason Gorman, Crystal Sao-Fong Cheung, Zhijian Duan, Li Ou, Maple Wang, Xuejun Chen, Cheng Cheng, Andrea Biju, Yaping Sun, Pengfei Wang, Yongping Yang, Baoshan Zhang, Jeffrey C. Boyington, Tatsiana Bylund, Sam Charaf, Steven J. Chen, Haijuan Du, Amy R. Henry, Tracy Liu, Edward K. Sarfo, Chaim A. Schramm, Chen-Hsiang Shen, Tyler Stephens, I-Ting Teng, John-Paul Todd, Yaroslav Tsybovsky, Raffaello Verardi, Danyi Wang, Shuishu Wang, Zhantong Wang, Cheng-Yan Zheng, Tongqing Zhou, Daniel C. Douek, John R. Mascola, David D. Ho, Mitchell Ho, Peter D. Kwong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Lassa virus (LASV) infection is expanding outside its traditionally endemic areas in West Africa, posing a pandemic biothreat. LASV-neutralizing antibodies, moreover, have proven difficult to elicit. To gain insight into LASV neutralization,
Externí odkaz:
https://doaj.org/article/83f13599c74f445ebfcd24f0985fef96
Autor:
Stephen M. Kissler, James A. Hay, Joseph R. Fauver, Christina Mack, Caroline G. Tai, Deverick J. Anderson, David D. Ho, Nathan D. Grubaugh, Yonatan H. Grad
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-7 (2023)
Abstract The impact of a prior SARS-CoV-2 infection on the progression of subsequent infections has been unclear. Using a convenience sample of 94,812 longitudinal RT-qPCR measurements from anterior nares and oropharyngeal swabs, we identified 71 ind
Externí odkaz:
https://doaj.org/article/3f1d1f8bc0de464083a926828fffe180
Autor:
Elsa W. Braunstein, Eric Vail, David D. Ho, Lihong Liu, Hiroshi Mohri, Matthew Gayhart, Glenn D. Braunstein
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 2, Pp n/a-n/a (2024)
Abstract Based upon clinical observations and recent reports, we anticipated there would be an inverse dose–response relationship between the severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2) viral load and the time‐to‐positivi
Externí odkaz:
https://doaj.org/article/0cde1ac6c73946c6b31f17238568ab1c
Autor:
Moriya Tsuji, Manoj S. Nair, Kazuya Masuda, Candace Castagna, Zhenlu Chong, Tamarand L. Darling, Kuljeet Seehra, Youngmin Hwang, Ágata Lopes Ribeiro, Geovane Marques Ferreira, Laura Corredor, Jordana Grazziela Alves Coelho-dos-Reis, Yukiko Tsuji, Munemasa Mori, Adrianus C. M. Boon, Michael S. Diamond, Yaoxing Huang, David D. Ho
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Prophylactic vaccines for SARS-CoV-2 have lowered the incidence of severe COVID-19, but emergence of viral variants that are antigenically distinct from the vaccine strains are of concern and additional, broadly acting preventive approaches
Externí odkaz:
https://doaj.org/article/3c17b40c03bf443c9109bfca507c868b
Autor:
Biao Zhou, Runhong Zhou, Jasper Fuk-Woo Chan, Jianwei Zeng, Qi Zhang, Shuofeng Yuan, Li Liu, Rémy Robinot, Sisi Shan, Na Liu, Jiwan Ge, Hugo Yat-Hei Kwong, Dongyan Zhou, Haoran Xu, Chris Chung-Sing Chan, Vincent Kwok-Man Poon, Hin Chu, Ming Yue, Ka-Yi Kwan, Chun-Yin Chan, Chris Chun-Yiu Chan, Kenn Ka-Heng Chik, Zhenglong Du, Ka-Kit Au, Haode Huang, Hiu-On Man, Jianli Cao, Cun Li, Ziyi Wang, Jie Zhou, Youqiang Song, Man-Lung Yeung, Kelvin Kai-Wang To, David D. Ho, Lisa A. Chakrabarti, Xinquan Wang, Linqi Zhang, Kwok-Yung Yuen, Zhiwei Chen
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Prevention of robust severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in nasal turbinate (NT) requires in vivo evaluation of IgA neutralizing antibodies. Here, we report the efficacy of receptor binding domain (RBD)-specific mon
Externí odkaz:
https://doaj.org/article/06e5de52ccad4802879063fc0fd250b8