Zobrazeno 1 - 10
of 120
pro vyhledávání: '"David Czock"'
Autor:
Josefine Kappe, Felix Wittmann, Melanie Luppa, Maria Isabel Cardona, Solveign Weise, Stephan Fuchs, Robert Philipp Kosilek, Linda Sanftenberg, Christian Brettschneider, Juliane Döhring, Catharina Escales, David Czock, Birgitt Wiese, Jochen René Thyrian, Wolfgang Hoffmann, Thomas Frese, Jochen Gensichen, Hans-Helmut König, Hanna Kaduszkiewicz, Steffi Gerlinde Riedel-Heller
Publikováno v:
BMC Primary Care, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background General practitioners (GPs) play a crucial role in identifying cognitive impairment and dementia and providing post-diagnostic care. This study investigates (1) how promising GP consider lifestyle changes to maintain cognitive per
Externí odkaz:
https://doaj.org/article/a7b91def9aa847c0bed783bcd2b0c067
Autor:
Camilo Scherkl, Andreas D. Meid, Sven E. Cuntz, Laura Classen, Johanna Weiss, David Czock, Walter E. Haefeli
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract Individual sirolimus whole blood concentrations are highly variable, critically influenced by the concomitant use of cytochrome P450 (CYP) 3A inducers or inhibitors, and also modulated by food. Therapeutic drug monitoring is therefore recomm
Externí odkaz:
https://doaj.org/article/29aa79bdc38c451f872ab11996092463
Publikováno v:
Pharmaceuticals, Vol 17, Iss 8, p 1041 (2024)
Quantitative systems pharmacology (QSP) models are rarely applied prospectively for decision-making in clinical practice. We therefore aimed to operationalize a QSP model for potas-sium homeostasis to predict potassium trajectories based on spironola
Externí odkaz:
https://doaj.org/article/49f14d149fb54fafbac5098900fc5904
Autor:
Matthias Schaier, Christian Morath, Lei Wang, Christian Kleist, Gerhard Opelz, Thuong Hien Tran, Sabine Scherer, Lien Pham, Naruemol Ekpoom, Caner Süsal, Gerald Ponath, Florian Kälble, Claudius Speer, Louise Benning, Christian Nusshag, Christoph F. Mahler, Luiza Pego da Silva, Claudia Sommerer, Angela Hückelhoven-Krauss, David Czock, Arianeb Mehrabi, Constantin Schwab, Rüdiger Waldherr, Paul Schnitzler, Uta Merle, Vedat Schwenger, Markus Krautter, Stephan Kemmner, Michael Fischereder, Manfred Stangl, Ingeborg A. Hauser, Anna-Isabelle Kälsch, Bernhard K. Krämer, Georg A. Böhmig, Carsten Müller-Tidow, Jochen Reiser, Martin Zeier, Michael Schmitt, Peter Terness, Anita Schmitt, Volker Daniel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe administration of modified immune cells (MIC) before kidney transplantation led to specific immunosuppression against the allogeneic donor and a significant increase in regulatory B lymphocytes. We wondered how this approach affected th
Externí odkaz:
https://doaj.org/article/e8a3a583d0ee42d7b2d399e91afea0aa
Autor:
Vanessa Zhu, Jürgen Burhenne, Johanna Weiss, Mathias Haag, Ute Hofmann, Matthias Schwab, Stephan Urban, Gerd Mikus, David Czock, Walter E. Haefeli, Antje Blank
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Bulevirtide is a first-in-class antiviral drug to treat chronic hepatitis B/D. We investigated the drug-drug interaction potential and pharmacokinetics of high-dose subcutaneous bulevirtide (5 mg twice daily) with organic anion transpor
Externí odkaz:
https://doaj.org/article/9dadd7a5884e42199ebe15eb6e6fa246
Autor:
Timolaos Rizos, Andreas D. Meid, Andrea Huppertz, Chris Dumschat, Jan Purrucker, Kathrin I. Foerster, Jürgen Burhenne, David Czock, Ekkehart Jenetzky, Peter A. Ringleb, Walter E. Haefeli
Publikováno v:
Journal of Stroke, Vol 24, Iss 1, Pp 88-97 (2022)
Background and purpose In acute stroke patients, plasma concentrations of direct oral anticoagulants (DOAC) at hospital admission only poorly mirror DOAC exposure or the coagulation status at the time of the event. Here, we evaluated whether DOAC exp
Externí odkaz:
https://doaj.org/article/86edab435408461b9a19d53330cd6373
Autor:
Andrea E. Zülke, Melanie Luppa, Susanne Röhr, Marina Weißenborn, Alexander Bauer, Franziska-Antonia Zora Samos, Flora Kühne, Isabel Zöllinger, Juliane Döhring, Christian Brettschneider, Anke Oey, David Czock, Thomas Frese, Jochen Gensichen, Walter E. Haefeli, Wolfgang Hoffmann, Hanna Kaduszkiewicz, Hans-Helmut König, Jochen René Thyrian, Birgitt Wiese, Steffi G. Riedel-Heller
Publikováno v:
BMC Geriatrics, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Objectives Growing evidence suggests a protective effect of high mental demands at work on cognitive function in later life. However, evidence on corresponding associations in older adults at increased risk for dementia is currently lacking.
Externí odkaz:
https://doaj.org/article/3d9e3b3c032a476abcfacf8ede479d39
Autor:
Lei Wang, Arianeb Mehrabi, Maria-Luisa Schubert, Anita Schmitt, Brigitte Neuber, Alexander Kunz, Angela Hückelhoven-Krauss, Carsten Müller-Tidow, Michael Schmitt, Christian Morath, Martin Zeier, Constantin Schwab, Anja Sander, Sabine Scherer, Claudius Speer, Christian Kleist, Claudia Sommerer, Florian Kälble, Christian Nusshag, Matthias Schaier, Louise Benning, Vedat Schwenger, Caner Süsal, Gerhard Opelz, T. Hien Tran, Stephan Kemmner, Michael Fischereder, Manfred Stangl, Ingeborg A. Hauser, Christian Bischofs, Sandra Sauer, Rüdiger Waldherr, Christopher Büsch, David Czock, Georg A Böhmig, Jochen Reiser, Axel Roers, Peter Terness, Volker Daniel
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction Donor-derived modified immune cells (MIC) induced long-term specific immunosuppression against the allogeneic donor in preclinical models of transplantation. In a phase I clinical trial (TOL-1 Study), MIC treatment resulted in a cellular
Externí odkaz:
https://doaj.org/article/6362680b60bd43139a9d0cb0059a65b3
Autor:
Ben Schöttker, Sabine Kuznia, Dana Clarissa Laetsch, David Czock, Annette Kopp-Schneider, Reiner Caspari, Hermann Brenner
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-16 (2020)
Abstract Background Cancer-related fatigue represents one major cause of reduced quality of life in cancer patients and can seriously affect the physical, emotional, and cognitive functioning impeding coping with the disease. Options for effective tr
Externí odkaz:
https://doaj.org/article/ca4784f5ef484b969697daf7ce6ce7f3
Autor:
Sabine Kuznia, David Czock, Annette Kopp-Schneider, Reiner Caspari, Harald Fischer, Dana Clarissa Laetsch, Marija Slavic, Hermann Brenner, Ben Schöttker
Publikováno v:
Nutrients, Vol 14, Iss 21, p 4546 (2022)
A personalized vitamin D3 loading dose has not yet been tested in cancer patients. This interim analysis of the randomized, placebo-controlled VICTORIA trial analyzed the first recruited 74 German adults with nonmetastatic colorectal cancer, a tumor
Externí odkaz:
https://doaj.org/article/835cb6dd73954dfd9d9fb5a75c27dc3d