Zobrazeno 1 - 7
of 7
pro vyhledávání: '"David Collares Achê"'
Autor:
Fernanda Van Petten de Vasconcelos Azevedo, Daiana Silva Lopes, Lara Vecchi, Denise de Oliveira Guimarães, Patrícia Terra Alves, Veridiana M. Rodrigues, David Collares Achê, Luiz Ricardo Goulart, Renata Santos Rodrigues, Sarah Natalie Cirilo Gimenes, Kelly Aparecida Geraldo Yoneyama
Publikováno v:
International Journal of Biological Macromolecules. 82:671-677
This work shows the antitumoral effects of BnSP-6, a Lys 49 PLA2 isolated from Bothrops pauloensis venom, on human breast cancer MDA-MB-231 cells. BnSP-6 caused a dose-dependent cytotoxicity and inhibited cell adhesion. Interestingly, cytotoxic activ
Autor:
Eliane C. Arantesa, Cristiane Bregge-Silva, Karla de Castro Figueiredo Bordon, José César Rosa, Veridiana M. Rodrigues, Johara Boldrini-França, Wagner Ferreira dos Santos, Renata Santos Rodrigues, David Collares Achê, Tibério Gracco Kazuhiro Perini, Caroline M. Cremonez, Dayane Lorena Naves de Souza, Francielle Almeida Cordeiro
Publikováno v:
Protein & Peptide Letters. 22:816-827
Phospholipases A2 (PLA2s) are enzymes responsible for inflammatory effects, edema formation, myotoxicity, neurotoxicity and other manifestations from envenoming. In this paper we report the isolation and biochemical characterization of Lmr-PLA2, the
Autor:
Denise de Oliveira Guimarães, Luiz Ricardo Goulart, Mário Sérgio Rocha Gomes, Makswell Almeida Silva, Renata Santos Rodrigues, Fernanda Van Petten de Vasconcelos Azevedo, Sarah Natalie Cirilo Gimenes, Lara Vecchi, Veridiana M. Rodrigues, Kelly Aparecida Geraldo Yoneyama, David Collares Achê, Daiana Silva Lopes
Publikováno v:
International journal of biological macromolecules. 97
Breast cancer is a highly malignant carcinoma and remains the second leading cause of mortality among women. The antitumor effects of metalloproteinases and disintegrins from snake venom on various types of cancer cells have been investigated. In thi
Autor:
Fernanda Van Petten Vasconcelos, Azevedo, Daiana Silva, Lopes, Sarah Natalie, Cirilo Gimenes, David Collares, Achê, Lara, Vecchi, Patrícia Terra, Alves, Denise de Oliveira, Guimarães, Renata Santos, Rodrigues, Luiz Ricardo, Goulart, Veridiana de Melo, Rodrigues, Kelly Aparecida Geraldo, Yoneyama
Publikováno v:
International journal of biological macromolecules. 82
This work shows the antitumoral effects of BnSP-6, a Lys 49 PLA2 isolated from Bothrops pauloensis venom, on human breast cancer MDA-MB-231 cells. BnSP-6 caused a dose-dependent cytotoxicity and inhibited cell adhesion. Interestingly, cytotoxic activ
Autor:
Isabela Pacheco Borges, Veridiana M. Rodrigues, David Collares Achê, Renata Santos Rodrigues, Sarah Natalie Cirilo Gimenes, Kelly Aparecida Geraldo Yoneyama, Dayane Lorena Naves de Souza, Daiana Silva Lopes, Letícia Eulalio Castanheira
Publikováno v:
Current topics in medicinal chemistry. 15(7)
Snake venoms constitute a mixture of bioactive components that are involved not only in envenomation pathophysiology but also in the development of new drugs to treat many diseases. Different enzymatic and non-enzymatic proteins, such as phospholipas
Autor:
Mário Sérgio Rocha Gomes, Veridiana M. Rodrigues, Dayane Lorena Naves de Souza, Kelly Aparecida Geraldo Yoneyama, Makswell Almeida Silva, Maria Inês Homsi Brandeburgo, Daiana Silva Lopes, Márcia Helena Borges, Renata Santos Rodrigues, David Collares Achê
Publikováno v:
International journal of biological macromolecules. 72
In the present work, we demonstrate some biochemical and functional properties of a new PI snake venom metalloproteinase (SVMP) isolated from Bothrops pauloensis snake venom (BpMP-II), in addition we evaluated its capacity to inhibit endothelial cell
Autor:
Mário Sérgio Rocha Gomes, David Collares Achê, Renata Santos Rodrigues, Márcia Helena Borges, Francis Barbosa Ferreira, Dayane Lorena Naves de Souza, Michael K. Richardson, Veridiana M. Rodrigues
Publikováno v:
Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology. 161(2)
Snake Venom Metalloproteinases (SVMPs) are the most abundant components present in Viperidae venom. They are important in the induction of systemic alterations and local tissue damage after envenomation. In the present study, a metalloproteinase name