Zobrazeno 1 - 10
of 93
pro vyhledávání: '"David Coelho"'
Autor:
Giulia M. Marchioro, David Coelho, Thibault Bouderlique, Daniel Abed-Navandi, Michael Schagerl, Cecilia D’Angelo, Luise Kruckenhauser, Igor Adameyko, Pedro R. Frade
Publikováno v:
Frontiers in Marine Science, Vol 11 (2024)
Reef-building corals have a variety of green fluorescent protein (GFP)-like proteins, also known as fluorescent proteins (FPs). These proteins have broad spectral properties covering most of the visible spectrum, with fluorophores fluorescing from cy
Externí odkaz:
https://doaj.org/article/ef8d49e28c63402da4f1419437934eef
Autor:
David Freitas, David Mota, David Coelho, Humberto Fontinele, Alexandre Coelho, Jarbas Silveira, Lirida Naviner, Joao Mota, Cesar Marcon
Publikováno v:
IEEE Access, Vol 12, Pp 131830-131841 (2024)
The diversity of nanosatellite applications is increasingly attracting the scientific community’s attention. The main component of these satellites is the OnBoard Computer (OBC), which is responsible for all control and processing. Also, OBC encomp
Externí odkaz:
https://doaj.org/article/84a0cbb491fe4fa884a21aa86d19abca
Autor:
Karim Matmat, Jean-Baptiste Conart, Paul-Henri Graindorge, Sandra El Kouche, Ziad Hassan, Youssef Siblini, Rémy Umoret, Ramia Safar, Okan Baspinar, Aurélie Robert, Jean-Marc Alberto, Abderrahim Oussalah, David Coelho, Jean-Louis Guéant, Rosa-Maria Guéant-Rodriguez
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-17 (2023)
Abstract Background MTR gene encodes the cytoplasmic enzyme methionine synthase, which plays a pivotal role in the methionine cycle of one-carbon metabolism. This cycle holds a significant importance in generating S-adenosylmethionine (SAM) and S-ade
Externí odkaz:
https://doaj.org/article/5befbbb86cbf45bca915fe1435c9c244
Autor:
Arnaud Wiedemann, Abderrahim Oussalah, Rosa-Maria Guéant Rodriguez, Elise Jeannesson, Marc Mertens, Irina Rotaru, Jean-Marc Alberto, Okan Baspinar, Charif Rashka, Ziad Hassan, Youssef Siblini, Karim Matmat, Manon Jeandel, Celine Chery, Aurélie Robert, Guillaume Chevreux, Laurent Lignières, Jean-Michel Camadro, François Feillet, David Coelho, Jean-Louis Guéant
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104911- (2024)
Summary: Background: The high variability in clinical and metabolic presentations of inborn errors of cobalamin (cbl) metabolism (IECM), such as the cblC/epicblC types with combined deficits in methylmalonyl-coA mutase (MUT) and methionine synthase (
Externí odkaz:
https://doaj.org/article/2d3ab102cea844078b893c2d92774c33
Autor:
Karim Matmat, Jean-Baptiste Conart, Paul-Henri Graindorge, Sandra El Kouche, Ziad Hassan, Youssef Siblini, Rémy Umoret, Ramia Safar, Okan Baspinar, Aurélie Robert, Jean-Marc Alberto, Abderrahim Oussalah, Sébastien Hergalant, David Coelho, Jean-Louis Guéant, Rosa-Maria Guéant-Rodriguez
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/90ae243dc7bf4338b25ff630391c4d92
Autor:
Ziad Hassan, David Coelho, Carine Bossenmeyer-Pourié, Karim Matmat, Carole Arnold, Aurélie Savladori, Jean-Marc Alberto, Rémy Umoret, Jean-Louis Guéant, Grégory Pourié
Publikováno v:
Cells, Vol 12, Iss 9, p 1267 (2023)
Impairment of one-carbon metabolism during pregnancy, either due to nutritional deficiencies in B9 or B12 vitamins or caused by specific genetic defects, is often associated with neurological defects, including cognitive dysfunction that persists eve
Externí odkaz:
https://doaj.org/article/4238e1b136d94a18b1cbbbcb39e748e3
Autor:
Jean-Louis Guéant, Céline Chéry, Abderrahim Oussalah, Javad Nadaf, David Coelho, Thomas Josse, Justine Flayac, Aurélie Robert, Isabelle Koscinski, Isabelle Gastin, Pierre Filhine-Tresarrieu, Mihaela Pupavac, Alison Brebner, David Watkins, Tomi Pastinen, Alexandre Montpetit, Fadi Hariri, David Tregouët, Benjamin A Raby, Wendy K. Chung, Pierre-Emmanuel Morange, D. Sean Froese, Matthias R. Baumgartner, Jean-François Benoist, Can Ficicioglu, Virginie Marchand, Yuri Motorin, Chrystèle Bonnemains, François Feillet, Jacek Majewski, David S. Rosenblatt
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Inborn errors of vitamin B12 metabolism of the cblC class are caused by mutations in the MMACHC gene. Here, Guéant et al. report epi-cblC, a class of cblC in which patients are compound heterozygous for a genetic mutation and a secondary epimutation
Externí odkaz:
https://doaj.org/article/cbd6be2fd8e245cb84a21aa02a029651
Autor:
Kristian K. Jensen, Marija Tadin-Strapps, Sheng-ping Wang, James Hubert, Yanqing Kan, Yong Ma, David G. McLaren, Stephen F. Previs, Kithsiri B. Herath, Ablatt Mahsut, Andy Liaw, Shubing Wang, Steven J. Stout, CarolAnn Keohan, Gail Forrest, David Coelho, Satya Yendluri, Stephanie Williams, Martin Koser, Steven Bartz, Karen O. Akinsanya, Shirly Pinto
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 12, Pp 2150-2162 (2016)
SREBP cleavage-activating protein (SCAP) is a key protein in the regulation of lipid metabolism and a potential target for treatment of dyslipidemia. SCAP is required for activation of the transcription factors SREBP-1 and -2. SREBPs regulate the exp
Externí odkaz:
https://doaj.org/article/bd0a1abbb701431196775362cf9f8457
Publikováno v:
Cells, Vol 9, Iss 8, p 1882 (2020)
Sirtuin1 (Sirt1) has a NAD (+) binding domain and modulates the acetylation status of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC1α) and Fork Head Box O1 transcription factor (Foxo1) according to the nutritional status. Sirt1
Externí odkaz:
https://doaj.org/article/61f5490dd81e49669933d6f8edbaec91
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2018)
In central nervous system, glycine receptor (GlyR) is mostly expressed in the spinal cord and brainstem, but glycinergic transmission related elements have also been identified in the brain. Astrocytes are active elements at the tripartite synapse, b
Externí odkaz:
https://doaj.org/article/c731c51a389341ddb13bd5f986c7996b