Pseudomonas aeruginosa MipA-MipB envelope proteins act as new sensors of polymyxins

Autor: Manon Janet-Maitre, Viviana Job, Maxime Bour, Mylène Robert-Genthon, Sabine Brugière, Pauline Triponney, David Cobessi, Yohann Couté, Katy Jeannot, Ina Attrée

Publikováno v: mBio, Vol 15, Iss 3 (2024)

ABSTRACT Due to the rising incidence of antibiotic-resistant infections, the last-line antibiotics, polymyxins, have resurged in the clinics in parallel with new bacterial strategies of escape. The Gram-negative opportunistic pathogen Pseudomonas aer

Externí odkaz: https://doaj.org/article/16a730f5b32f4089bc94e6f64358345a

Crystal Structure of the Chloroplastic Oxoene Reductase ceQORH from Arabidopsis thaliana

Autor: Sarah Mas y mas, Gilles Curien, Cécile Giustini, Norbert Rolland, Jean-Luc Ferrer, David Cobessi

Publikováno v: Frontiers in Plant Science, Vol 8 (2017)

Enzymatic and non-enzymatic peroxidation of polyunsaturated fatty acids give rise to accumulation of aldehydes, ketones, and α,β-unsaturated carbonyls of various lengths, known as oxylipins. Oxylipins with α,β-unsaturated carbonyls are reactive e

Externí odkaz: https://doaj.org/article/520dc6b06e194e22bb87d05f2815b735

Three-dimensional envelope and subunit interactions of the plastid-encoded RNA polymerase from Sinapis alba

Autor: Rémi Ruedas, Yohann Couté, Sylvie Kieffer-Jacquinod, Soumiya Sankari Muthukumar, François-Xavier Gillet, Daphna Fenel, Grégory Effantin, Thomas Pfannschmidt, Robert Blanvillain, David Cobessi

RNA polymerases (RNAPs) involved in gene transcription are found in all living organisms with degrees of complexity ranging from single polypeptide chains to multimeric enzymes. In the chloroplasts, the nuclear-encoded RNA polymerase and the plastid-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89e482f9b20850c9662571e731cf459d
https://doi.org/10.1101/2022.05.04.490580

The Plastid-Encoded RNA Polymerase-Associated Protein PAP9 Is a Superoxide Dismutase With Unusual Structural Features

Autor: Elisabetta Boeri Erba, David Cobessi, Robert Blanvillain, Luca Signor, Soumiya Sankari Muthukumar, Thomas Pfannschmidt, Pierre Gans, Adrien Favier

Publikováno v: Frontiers in Plant Science
Frontiers in Plant Science, Frontiers, 2021, 12, pp.668897. ⟨10.3389/fpls.2021.668897⟩
'Frontiers in Plant Science ', vol: 12, pages: 668897-1-668897-15 (2021)
Frontiers in Plant Science, 2021, 12, pp.668897. ⟨10.3389/fpls.2021.668897⟩
Frontiers in Plant Science, Vol 12 (2021)

In Angiosperms, the plastid-encoded RNA polymerase (PEP) is a multimeric enzyme, essential for the proper expression of the plastid genome during chloroplast biogenesis. It is especially required for the light initiated expression of photosynthesis g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6107e25e7842463741d2a659c4656e
https://hal.archives-ouvertes.fr/hal-03313484/document

Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1β aspartate aminotransferase

Autor: Gilles Curien, Cécile Giustini, Matthieu Graindorge, David Cobessi, Michel Matringe, Adeline Robin, Serge Crouzy

Publikováno v: FEBS Journal
FEBS Journal, Wiley, 2019, 286 (11), pp.2118-2134. ⟨10.1111/febs.14789⟩
FEBS Journal, 2019, 286 (11), pp.2118-2134. ⟨10.1111/febs.14789⟩

International audience; Alternative routes for the post-chorismate branch of the biosynthetic pathway leading to tyrosine exist, the 4-hydroxyphenylpyruvate or the arogenate route. The arogenate route involves the transamination of prephenate into ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::053b0ac2aacf3907ab1a975b574d97ec
https://hal.archives-ouvertes.fr/hal-02093098