Zobrazeno 1 - 10
of 76
pro vyhledávání: '"David Clicq"'
Publikováno v:
Journal of chromatography. A. 1526
A supercritical chromatographic method for the separation of a drug and its impurities has been developed and optimized applying an experimental design approach and chromatogram simulations. Stationary phase screening was followed by optimization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a972242983c1f30968b66714e741be25
https://pubmed.ncbi.nlm.nih.gov/29054437
https://pubmed.ncbi.nlm.nih.gov/29054437
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 83:194-201
The final step of an active pharmaceutical ingredient (API) manufacturing synthesis process consists of a crystallization during which the API and residual solvent contents have to be quantified precisely in order to reach a predefined seeding point.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f8092e2a55cf9cea2a5820c635a7ec
https://doi.org/10.1016/j.jpba.2013.05.015
https://doi.org/10.1016/j.jpba.2013.05.015
Publikováno v:
Analytical Chemistry. 83:966-975
A variable length method development (or VL-MD)strategy, exploiting the potential of an automatic column coupling system, is proposed and has been applied to a number of different pharmaceutical and environmental samples with a varying degree of comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70ef67ab67ce6a3614c2c32cc920e4d
https://doi.org/10.1021/ac102508h
https://doi.org/10.1021/ac102508h
Publikováno v:
Journal of Chromatography A. 1203:124-136
The use of ultra-high pressure liquid chromatography (UHPLC) with pressures up to 1000 bar and columns packed with sub-2-microm particles combined with high-temperature mobile phase conditions (up to 90 degrees C) is assessed according to the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc926cf88645eec46c9b202037a78141
https://doi.org/10.1016/j.chroma.2008.07.039
https://doi.org/10.1016/j.chroma.2008.07.039
Publikováno v:
Vrije Universiteit Brussel
Analytical chemistry, 79(2007), 5915-5926. American Chemical Society
Analytical chemistry, 79(2007), 5915-5926. American Chemical Society
Building upon the micromachined column idea proposed by the group of Regnier in 1998, we report on the first high-resolution reversed-phase separations in micromachined pillar array columns under pressure-driven LC conditions. A three component mixtu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435403663333be39af0aeac5fa32dc75
https://doi.org/10.1021/ac070352p
https://doi.org/10.1021/ac070352p
Publikováno v:
Journal of Chromatography A. 1146:193-201
Using a set of experimentally determined plate height data obtained on three commercial high-temperature HPLC supports, and evaluating their isocratic separation speed potential under the application of a set of instrumental constraints, a qualitativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::103b9fea34525089bb2f60ed7e42a453
https://doi.org/10.1016/j.chroma.2007.02.042
https://doi.org/10.1016/j.chroma.2007.02.042
Publikováno v:
Journal of Chromatography A. 1143:121-133
The present study aimed at mapping the separation speed potential of a critical pair on commercial high-temperature HPLC (HT-HPLC) supports at elevated temperatures. For this purpose, band broadening and pressure drop measurements were conducted on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60f4f27494118649f725346dddbca8b0
https://doi.org/10.1016/j.chroma.2006.12.101
https://doi.org/10.1016/j.chroma.2006.12.101
Publikováno v:
Journal of chromatography A, 1149(1), 2-11. Elsevier
The present paper reports on the experimental difficulties encountered when trying to realize the full potential of shear-driven chromatography in nanochannels. While it theoretically offers the possibility to yield over 10,000 plates per centimetre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7b0a7560c1de4ddf1394a5aaee72b9
https://doi.org/10.1016/j.chroma.2007.01.120
https://doi.org/10.1016/j.chroma.2007.01.120
Publikováno v:
Journal of chromatography A, 1130(1), 151-157. Elsevier
The present paper reports on an experimental study of the possibility to use a micro-machined detection groove to enhance the detection sensitivity in flat-rectangular nano-channels for ultra-rapid liquid chromatography separations. Transversally run
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222ecdbbf76165ae55bd4328b87e3d1a
https://doi.org/10.1016/j.chroma.2006.05.087
https://doi.org/10.1016/j.chroma.2006.05.087
Autor:
Johannes G.E. Gardeniers, David Clicq, H. Eghbati, D.M.W. De Malsche, Veronika Fekete, Gert Desmet
Publikováno v:
Lab on a chip, 6(10/10):10.1039/b607683a, 1322-1327. Royal Society of Chemistry
This paper describes a method to automatically and reproducibly inject sharply delimited sample plugs in the shallow (i.e., sub-micron) channels typically used in shear driven chromatography. The formation of asymmetric plugs, which typically occurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc29a7049a20d1249ee7408fe2d6796b
https://doi.org/10.1039/b607683a
https://doi.org/10.1039/b607683a