Zobrazeno 1 - 10
of 398
pro vyhledávání: '"David Clayton"'
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/10f6c870977448e680772a0233d88b71
Autor:
Arlene Astell, David Clayton
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
This community case study examined the potential benefits of smart speakers to tackle loneliness in the oldest old adults living in supported accommodation. The program was established as a collaboration between the supported accommodation provider a
Externí odkaz:
https://doaj.org/article/ea029fff7c214525b4d866f51e70de06
Autor:
Anitha Priya Krishnan, Zhuang Song, David Clayton, Xiaoming Jia, Alex de Crespigny, Richard A. D. Carano
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract T2 lesion quantification plays a crucial role in monitoring disease progression and evaluating treatment response in multiple sclerosis (MS). We developed a 3D, multi-arm U-Net for T2 lesion segmentation, which was trained on a large, multic
Externí odkaz:
https://doaj.org/article/61222861b5b4417f977122a410927cd6
Myelin water imaging in relapsing multiple sclerosis treated with ocrelizumab and interferon beta-1a
Autor:
Shannon Kolind, Shawna Abel, Carolyn Taylor, Roger Tam, Cornelia Laule, David K.B. Li, Hideki Garren, Laura Gaetano, Corrado Bernasconi, David Clayton, Irene Vavasour, Anthony Traboulsee
Publikováno v:
NeuroImage: Clinical, Vol 35, Iss , Pp 103109- (2022)
Background: Myelin water imaging is a magnetic resonance imaging (MRI) technique that quantifies myelin damage and repair in multiple sclerosis (MS) via the myelin water fraction (MWF). Objective: In this substudy of a phase 3 therapeutic trial, OPER
Externí odkaz:
https://doaj.org/article/be50f8ccff20491dac691d5ad23af4ff
Autor:
Zhuang Song, Anithapriya Krishnan, Laura Gaetano, Nicholas J. Tustison, David Clayton, Alex de Crespigny, Thomas Bengtsson, Xiaoming Jia, Richard A.D. Carano
Publikováno v:
NeuroImage: Clinical, Vol 34, Iss , Pp 102959- (2022)
Background: Despite advancements in treatments for multiple sclerosis, insidious disease progression remains an area of unmet medical need, for which atrophy-based biomarkers may help better characterize the progressive biology. Methods: We developed
Externí odkaz:
https://doaj.org/article/f33d9eb048974392882708206b4b1e98
Publikováno v:
Frontiers in Psychology, Vol 12 (2021)
Methods to facilitate co-production in mental health are important for engaging end users. As part of the Technology for Healthy Aging and Wellbeing (THAW) initiative we organized two interactive co-production workshops, to bring together older adult
Externí odkaz:
https://doaj.org/article/9c957ed49b2e4e43bae4f0aa161c6adf
Autor:
David Clayton, Alexandre Coimbra, Farshid Faraji, Thomas Bengtsson, Lee Honigberg, William Cho, Robert Paul, Alex de Crespigny
Publikováno v:
Neuroimage: Reports, Vol 1, Iss 4, Pp 100055- (2021)
Resting-state functional connectivity has been used to study Alzheimer's disease, revealing underlying differences between groups of individuals at different levels of cognitive impairment, or groupwise changes over time. Most of these studies have e
Externí odkaz:
https://doaj.org/article/0385cf08fb4d43de8c03a5d982256ba0
Autor:
Valentina Ghisays, Francisco Lopera, Dhruman D. Goradia, Hillary D. Protas, Michael H. Malek-Ahmadi, Yinghua Chen, Vivek Devadas, Ji Luo, Wendy Lee, Ana Baena, Yamile Bocanegra, Edmarie Guzmán-Vélez, Enmanuelle Pardilla-Delgado, Clara Vila-Castelar, Joshua T. Fox-Fuller, Nan Hu, David Clayton, Ronald G. Thomas, Sergio Alvarez, Alejandro Espinosa, Natalia Acosta-Baena, Margarita M. Giraldo, Silvia Rios-Romenets, Jessica B. Langbaum, Kewei Chen, Yi Su, Pierre N. Tariot, Yakeel T. Quiroz, Eric M. Reiman
Publikováno v:
NeuroImage: Clinical, Vol 31, Iss , Pp 102749- (2021)
Background: In contrast to sporadic Alzheimer’s disease, autosomal dominant Alzheimer’s disease (ADAD) is associated with greater neuropathological evidence of cerebellar amyloid plaque (Aβ) deposition. In this study, we used positron emission t
Externí odkaz:
https://doaj.org/article/ca4232c78c6242d88233825d2f292caa
Autor:
Stephen Salloway, Lee A. Honigberg, William Cho, Michael Ward, Michel Friesenhahn, Flavia Brunstein, Angelica Quartino, David Clayton, Deborah Mortensen, Tobias Bittner, Carole Ho, Christina Rabe, Stephen P. Schauer, Kristin R. Wildsmith, Reina N. Fuji, Shehnaaz Suliman, Eric M. Reiman, Kewei Chen, Robert Paul
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2018)
Abstract Background We investigated the effect of crenezumab, a humanized anti-amyloid-beta (Aβ) immunoglobulin (Ig)G4 monoclonal antibody, on biomarkers of amyloid pathology, neurodegeneration, and disease progression in patients with mild-to-moder
Externí odkaz:
https://doaj.org/article/a311ee7ca9264e6696bffa8520f93ab9