Zobrazeno 1 - 10
of 10
pro vyhledávání: '"David Ciccone"'
Autor:
Scott Daigle, David Ciccone, Samantha Carreiro, Christine Loh, Neelu Kaila, Fu-Shan Kuo, Scott Boiko, Gene Yau, Esha A Gangolli, Denise Levasseur, Bhaskar Srivastava, Frank G Basile
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d7116d7f7b804a0885f65ce7d1bf0e25
Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses
Autor:
Giulia Monticone, Zhi Huang, Fred Csibi, Silvana Leit, David Ciccone, Ameya S. Champhekar, Jermaine E. Austin, Deniz A. Ucar, Fokhrul Hossain, Salome V. Ibba, A. Hamid Boulares, Nicholas Carpino, Keli Xu, Samarpan Majumder, Barbara A. Osborne, Christine Loh, Lucio Miele
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
A critical feature of cancer is the ability to induce immunosuppression and evade immune responses. Tumor-induced immunosuppression diminishes the effectiveness of endogenous immune responses and decreases the efficacy of cancer immunotherapy. In thi
Externí odkaz:
https://doaj.org/article/f8e940e37817407f8336c28c349fbf51
Autor:
David Ciccone, Vad Lazari, Ian Linney, Michael Briggs, Samantha Carreiro, Joshua McElwee, Ian Waddell, Chris Hill, Christine Loh, Peter Tummino, Alan Collis, Neelu Kaila
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/11f4cb29b7ee40dfb6994ec7c3098018
Autor:
Silvana Leit, David Ciccone
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Giulia Monticone, Fred Csibi, Silvana Leit, David Ciccone, Ameya S. Champhekar, Jermaine E. Austin, Deniz A. Ucar, Fokhrul Hossain, Zhi Huang, Salome V. Ibba, A. Hamid Boulares, Nicholas Carpino, Samarpan Majumder, Keli Xu, Barbara A. Osborne, Christine Loh, Lucio Miele
A critical feature of cancer is the ability to induce immunosuppression and evade immune responses. Tumor-induced immunosuppression diminishes the efficacy of endogenous immune responses and decreases the efficacy of cancer immunotherapy. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f1499160016e9fd40cbe8738775d92d
https://doi.org/10.1101/2022.03.15.484378
https://doi.org/10.1101/2022.03.15.484378
Autor:
Joshua McElwee, Vad Lazari, Peter Tummino, Chris Hill, Ian D. Waddell, Ian Linney, Neelu Kaila, Christine Loh, Alan Collis, David Ciccone, Samantha Carreiro, Michael Briggs
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background HPK1, a member of the MAP4K family of protein serine/threonine kinases, is involved in regulating signal transduction cascades in cells of hematopoietic origin. Recent data from HPK1 knockout animals and kinase-inactive knock-in animals un
Autor:
Neelu Kaila, Vad Lazari, Michael Briggs, Alan Collis, Ian Linney, Samantha Carreiro, Peter Tummino, Christine Loh, David Ciccone, Joshua J McElwee
Publikováno v:
Cancer Research. 81:1649-1649
Background: HPK1, a member of the MAP4K family of protein serine/threonine kinases, is involved in negatively regulating signal transduction cascades in cells of hematopoietic origin. Recent data generated using potent and highly selective HPK1 inhib
Autor:
David Ciccone, C. Loh, Samantha Carreiro, Alan Collis, Vad Lazari, Ian Linney, Peter Tummino, Neelu Kaila, Ian D. Waddell, Chris Hill, Michael Briggs
Publikováno v:
European Journal of Cancer. 138:S20
Autor:
John Montana, Neelu Kaila, Mark Ashwell, Michael Briggs, Jennifer Rocnik, David Ciccone, Vad Lazari, Peter Tummino, Ian Linney, Christine Loh, Alan Collis
Publikováno v:
Cancer Research. 80:942-942
Introduction: HPK1, a member of the MAP4K family of protein serine/threonine kinases, is involved in regulating signal transduction cascades in cells of hematopoietic lineage. Recent data from HPK1 knockout animals and kinase-inactive knock-in animal
Autor:
David, Ciccone, Marjorie, Oettinger
Publikováno v:
Novartis Foundation symposium. 259
Changes in chromatin structure play a key role in the regulation of the mammalian genome, governing diverse processes including transcription, replication and recombination. In the earliest stages of antigen receptor assembly, D and J segments of the