Zobrazeno 1 - 10
of 34
pro vyhledávání: '"David Catterick"'
Autor:
Michelle Gleeson, Mark Danese, Eduard Sidelnikov, Guillermo Villa, David Catterick, Mazhar Iqbal, Deborah Lubeck, Jeetesh Patel
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Objectives To compare treatment patterns, risk factors and cardiovascular disease (CVD) event rates in the UK from 2008 to 2017.Design Retrospective cohort study using the Clinical Practice Research Datalink.Setting UK primary care.Participants We se
Externí odkaz:
https://doaj.org/article/49c3dce06fd44dbfb87dbb86aab6c47f
Autor:
Mark Danese, Eduard Sidelnikov, Guillermo Villa, David Catterick, Mazhar Iqbal, Michelle Gleeson, Deborah Lubeck, Jeetesh Patel
Publikováno v:
BMJ open. 12(4)
ObjectivesTo compare treatment patterns, risk factors and cardiovascular disease (CVD) event rates in the UK from 2008 to 2017.DesignRetrospective cohort study using the Clinical Practice Research Datalink.SettingUK primary care.ParticipantsWe select
Autor:
Beverly J. Hunt, David Catterick
Publikováno v:
Blood Coagulation & Fibrinolysis
Venous thromboembolism (VTE) is a common and important cause of death in hospital patients. We therefore investigated possible associations between the introduction of the compulsory national VTE risk assessment tool in England in 2010 and patient ou
Autor:
David Catterick, Alec Simpson, Clive E. Mountain, Nick F. Wooster, Chris McCormick, Stuart G. Leach, Hugh Britton, Andrew H. Gordon, John Warren, Audrey Zilliox, Charles E. Wade, Michael W. J. Urquhart, David R. Stevens, Andrew Neil Dwyer
Publikováno v:
Organic Process Research & Development. 16:1607-1617
The discovery and development of an efficient and more sustainable manufacturing route to the anti-pneumocystic agent atovaquone (2-((1R,4R)-4-(4-chlorophenyl)cyclohexyl)-3-hydroxynaphthalene-1,4-dione) 1 is described. The existing commercial route t
Autor:
Mariola Gordo, Elena Sandoval, Jose M. Coteron, Jiri Gut, Beatriz Hernández Díaz, María J. Chaparro, Jennifer Legac, Santiago Ferrer, David Catterick, Julia Castro, Juan Miguel, Maria L. Marco, Pilar Ventosa, Philip J. Rosenthal, Vicente Muñoz, Jose M. Fiandor, José Ruiz, Juan C. de la Rosa, Francisco J. Gamo, Esther Porras, Esther Fernández, Laura Fernández de las Heras
Publikováno v:
Journal of Medicinal Chemistry. 53:6129-6152
Falcipain-2 and falcipain-3 are papain-family cysteine proteases of the malaria parasite Plasmodium falciparum that are responsible for host hemoglobin hydrolysis to provide amino acids for parasite protein synthesis. Different heteroarylnitrile deri
Autor:
Anthony G. M. Barrett, D. Christopher Braddock, Andrew J. P. White, Nathalie Bouloc, David Catterick, David J. Williams, David Chadwick
Publikováno v:
Tetrahedron. 58:3835-3840
Full experimental details are given for the preparation of highly active catalysts Yb[C(SO2C4F9)3]3, Yb[C(SO2C6F13)3]3, and Yb[C(SO2C6F13)2SO2C8F17]3.
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :668-679
The reaction of diamines and amidrazones with α-amino acid vicinal tricarbonyls has been shown to be a versatile route towards novel heterocyclic α-amino acids. This route is also applicable to parallel synthesis and has allowed the formation of a
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :299-302
A range of novel heterocyclic α-amino acids has been synthesised by the reaction of diamines and amidrazones with α-amino acid vicinal tricarbonyl reactive substrates.
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2311-2316
A series of novel non-proteinogenic heterocyclic substituted α-amino acids derived from L-aspartic acid have been synthesised using the alkynyl ketone functionality as a versatile building block. Condensation of (S)-2-tert-butoxycarbonylamino-4-oxoh
The synthesis of pyrimidin-4-yl substituted α-amino acids. A versatile approach from alkynyl ketones
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :855-866
The reaction of amidines with α-amino acid alkynyl ketones is shown to be a versatile route to pyrimidin-4-yl substituted α-amino acids. This route is also applicable to a parallel synthesis approach and has allowed the formation of a range of pyri