Zobrazeno 1 - 10
of 156
pro vyhledávání: '"David C.W. Lau"'
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 2, Pp 424-429 (2003)
Cyclooxygenase (COX) catalyses the rate-limiting step of prostanoid biosynthesis. Two COX isoforms have been identified, COX-1, the constitutive form, and COX-2, the inducible form. While COX-2 has been implicated in body fat regulation, the underlyi
Externí odkaz:
https://doaj.org/article/f17bdc057d0846749062e9089137a7e6
Autor:
Hongyun Yan, Edith Aziz, Gillian Shillabeer, Alex Wong, Deena Shanghavi, Abdenaim Kermouni, Mohammed Abdel-Hafez, David C.W. Lau
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 12, Pp 2123-2129 (2002)
The putative role of nitric oxide (3333333333333333335) in modulating adipogenesis was investigated in cultured preadipocytes derived from rat white adipose tissue. The NO releasing reagent, hydroxylamine (HA), and nitric oxide synthase (NOS) substra
Externí odkaz:
https://doaj.org/article/1b60fdcab5524cd98a4ca6379a01d3ff
Autor:
Rahul Jain, James A. Stone, Gina Agarwal, Jason G. Andrade, Simon L. Bacon, Harpreet S. Bajaj, Brian Baker, Gemma Cheng, David Dannenbaum, Mark Gelfer, Jeffrey Habert, John Hickey, Karim Keshavjee, Darlene Kitty, Patrice Lindsay, Mary R. L’Abbé, David C.W. Lau, Laurent Macle, Michael McDonald, Kara Nerenberg, Glen J. Pearson, Thuy Pham, Alexandre Y. Poppe, Doreen M. Rabi, Diana Sherifali, Peter Selby, Eric Smith, Sol Stern, George Thanassoulis, Kristin Terenzi, Karen Tu, Jacob Udell, Sean A. Virani, Richard A. Ward, Darren E.R. Warburton, Sean Wharton, Jennifer Zymantas, Diane Hua-Stewart, Peter P. Liu, Sheldon W. Tobe
Publikováno v:
Canadian Medical Association Journal. 195:E21-E42
Autor:
Rahul Jain, James A. Stone, Gina Agarwal, Jason G. Andrade, Simon L. Bacon, Harpreet S. Bajaj, Brian Baker, Gemma Cheng, David Dannenbaum, Mark Gelfer, Jeffrey Habert, John Hickey, Karim Keshavjee, Darlene Kitty, Patrice Lindsay, Mary R. L’Abbé, David C.W. Lau, Laurent Macle, Michael McDonald, Kara Nerenberg, Glen J. Pearson, Thuy Pham, Alexandre Y. Poppe, Doreen M. Rabi, Diana Sherifali, Peter Selby, Eric Smith, Sol Stern, George Thanassoulis, Kristin Terenzi, Karen Tu, Jacob Udell, Sean A. Virani, Richard A. Ward, Darren E.R. Warburton, Sean Wharton, Jennifer Zymantas, Diane Hua-Stewart, Peter P. Liu, Sheldon W. Tobe
Publikováno v:
CMAJ
Autor:
David C.W. Lau, Domenica Rubino, Kasper K Berthelsen, Michael T. Lund, Martin Kankam, Altynai Satylganova, Lone B Enebo
Publikováno v:
The Lancet. 397:1736-1748
Summary Background Cagrilintide, a long-acting amylin analogue, and semaglutide 2·4 mg, a glucagon-like peptide-1 analogue, are both being investigated as options for weight management. We aimed to determine the safety, tolerability, pharmacokinetic
Autor:
Leah Walker, Megha Poddar, Sanjeev Sockalingam, Christian F. Rueda-Clausen, Sean Wharton, Michael E. Green, Kristi B. Adamo, Sue Pedersen, Denis Prud’homme, Michel Gagner, Ian Patton, Angela S. Alberga, Dennis Hong, Laurie Twells, Raed Hawa, Marie-France Langlois, Ellen L. Toth, Mary Forhan, Ian Janssen, Marie-Philippe Morin, Cindy Grand, Dennis Divalentino, Carol Clarke, Margaret Hahn, Denise Campbell-Scherer, Carlene Johnson-Stoklossa, Priya Manjoo, Jennifer L. Kuk, John L. Sievenpiper, Leen Naji, Elaine Boyling, Pam Hung, Judy Shiau, Kara Nerenberg, David C.W. Lau, Scott Lear, Shelly Russell-Mayhew, Diana Sherifali, Jennifer Brown, Laurent Biertho, Leticia Pereira, Sonja Wicklum, Michael Vallis, Ashley McInnes, Richard Tytus, Rita Henderson, David Macklin, Yoni Freedhoff, Helena Piccinini-Vallis, Amy Kemp, Kristen Jacklin, Normand G. Boulé, Stephen Glazer, Ximena Ramos Salas, Shahebina Walji, Betty Calam, Arya M. Sharma, Rhonda Bell, Lindsay Crowshoe, Valerie H. Taylor, Paul Poirier, Sara F. L. Kirk
Publikováno v:
CMAJ
POINTS CLES L’obesite est une maladie chronique complexe dans laquelle la graisse corporelle anormale ou excessive (adiposite) nuit a la sante, augmente le risque de complications medicales a long terme et reduit la duree de vie[1][1]. Les etudes e
Autor:
Kristen Jacklin, Leah Walker, Michael E. Green, Stephen Glazer, Betty Calam, Kristi B. Adamo, Valerie H. Taylor, Denis Prud'homme, Lindsay Crowshoe, Richard Tytus, Michel Gagner, Paul Poirier, Angela S. Alberga, Jennifer L. Kuk, Elaine Boyling, Dennis Divalentino, Cindy Grand, Scott Lear, Laurie Twells, Raed Hawa, Carol Clarke, Judy Shiau, David Macklin, Yoni Freedhoff, Megha Poddar, Helena Piccinini-Vallis, Normand G. Boulé, Leticia Pereira, Priya Manjoo, Pam Hung, Sara F. L. Kirk, Ian Patton, Shelly Russell-Mayhew, Arya M. Sharma, Rhonda Bell, Diana Sherifali, Shahebina Walji, David C.W. Lau, Mary Forhan, Sonja Wicklum, Sanjeev Sockalingam, Sue Pedersen, Dennis Hong, Laurent Biertho, Marie-France Langlois, Ellen L. Toth, Kara Nerenberg, Michael Vallis, Ian Janssen, Ashley McInnes, Rita Henderson, Amy Kemp, Jennifer Brown, Ximena Ramos Salas, Margaret Hahn, Denise Campbell-Scherer, Leen Naji, Sean Wharton, John L. Sievenpiper, Marie-Philippe Morin, Christian F. Rueda-Clausen, Carlene Johnson-Stoklossa
Publikováno v:
CMAJ : Canadian Medical Association Journal
KEY POINTS Obesity is a complex chronic disease in which abnormal or excess body fat (adiposity) impairs health, increases the risk of long-term medical complications and reduces lifespan.[1][1] Epidemiologic studies define obesity using the body mas
Autor:
Stefan Kabisch, Dario Rahelić, Leanne Harris, Michael E. J. Lean, Sean Wharton, Arya M. Sharma, Zhila Semnani-Azad, Lawrence A. Leiter, Tauseef Khan, Hana Kahleova, David C.W. Lau, John L. Sievenpiper, Cyril W.C. Kendall, Jordi Salas-Salvadó
Publikováno v:
Curr Dev Nutr
OBJECTIVES: Intermittent fasting (IF) is a popular trending diet, yet there is limited evidence-based support considering its clinical impact on cardiometabolic outcomes. In an effort to inform the European Association for the Study of Diabetes (EASD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55067179eb08142779b5ef555ec547d
https://europepmc.org/articles/PMC8181501/
https://europepmc.org/articles/PMC8181501/
Autor:
Sue D. Pedersen, Kirsi H. Pietiläinen, Barbara McGowan, Rachel L. Batterham, Ann Marie Ocampo Francisco, Altynai Satylganova, Carel W. le Roux, David C.W. Lau, Domenica Rubino, Lars Erichsen
Publikováno v:
Lancet (London, England). 398(10317)
Summary Background Natural amylin is a pancreatic hormone that induces satiety. Cagrilintide is a long-acting amylin analogue under investigation for weight management. We assessed the dose–response relationship of cagrilintide regarding the effect
Autor:
Lone B Enebo, Martin Kankam, David C.W. Lau, Michael T. Lund, Kasper K Berthelsen, Domenica Rubino, Altynai Satylganova
Publikováno v:
Journal of the Endocrine Society
Background: Combining weight management medications with different modes of action may provide more effective treatment options for people with obesity. Subcutaneous (sc) AM833, a long-acting amylin analog, and sc semaglutide 2.4 mg, a glucagon-like