Zobrazeno 1 - 10
of 54
pro vyhledávání: '"David C. Stump"'
Publikováno v:
Transfusion. 42:27-36
HES solutions provide a sterile, alternative colloidal fluid to albumin solutions and/or plasma in the management of patients who need plasma volume expansion. Solutions of HES are widely accepted internationally but are used only modestly in the Uni
Publikováno v:
American Heart Journal. 141:542-547
The Data and Safety Monitoring Committee (DSMC) constitutes one of the most complex elements of a clinical trial. For this reason, it is critical that all participants in and contributors to a trial understand the functions and responsibilities of th
Autor:
Erich Bluhmki, Christopher P. Cannon, C. Michael Gibson, NL Fox, S Berioli, Frans Van de Werf, Eugene Braunwald, F Wang-Clow, Thierry Danays, David C. Stump
Publikováno v:
American Heart Journal. 141:33-40
TNK-tissue plasminogen activator (TNK-tPA) is a potent new thrombolytic agent for treatment of acute myocardial infarction. TNK-tPA was evaluated in 4214 patients in two dose-ranging trials (Thrombolysis in Myocardial Infarction [TIMI] 10B and Assess
Publikováno v:
American Heart Journal. 137:S90-S93
Autor:
George Sopko, Barry L. Zaret, Christopher P. Cannon, Kenneth G. Mann, Edward F. Mahan, David C. Stump, David O. Williams, Bruce Thompson, Russell P. Tracy, William J. Rogers, Neal S. Kleiman, Desire Collen, Edwin G. Bovill, R.Greg Brown
Publikováno v:
American Heart Journal. 135:29-37
Current protocols for use of tissue-type plasminogen activator in acute myocardial infarction include heparin estimated by the activated partial thromboplastin time (aPTT). Recent reports indicate a risk of recurrent ischemic events with long aPTT va
Publikováno v:
Research-Technology Management. 36:27-35
Eastman Chemical Company (ECC) has long recognized the importance of innovating products and processes in a manufacturing environment (1). However, as a direct result of our quality effort that began in the early 1980s, we became increasingly concern
Autor:
Edwin G. Bovill, Wendy Werner, Frank W. Torres, Harry D. Garabedian, Agha Khan, John B. Newell, Robert C. Leinbach, David C. Stump, Herman K. Gold, J.Nathan Hagstrom, Tsunehiro Yasuda, Ik-Kyung Jang, Desire Collen
Publikováno v:
Journal of the American College of Cardiology. 21(5):1039-1047
Objectives. In a Phase I clinical trial, we studied the antithrombotic and clinical effects of the synthetic competitive thrombin inhibitor, argatroban, in 43 patients with unstable angina pectoris. Background. Thrombin has a pivotal rote in platelet
Autor:
Stephen G. Ellis, Eric J. Topol, Kristina N. Sigmon, David C. Stump, Dean J. Kereiakes, Thomas C. Wall, Richard S. Stack, Robert M. Califf, Joseph Samaha, David C. Sane, Barry S. George
Publikováno v:
Journal of the American College of Cardiology. 21:597-603
Objectives. The aim of this study was to assess the hemorrhagic risk associated with fibrin-specific thrombolytic therapy and invasive procedures with acute myocardial infarction.Background. Successful coronary artery reperfusion has important progno
Autor:
Stephen G. Ellis, Kristina N. Sigmon, Dean J. Kereiakes, Thomas C. Wall, Eric J. Topol, Robert M. Califf, Lynn H. Woodlief, Jeffrey L. Anderson, Jeffrey J. Popma, Joseph Samaha, Barry S. George, David C. Stump, Seth J. Worley
Publikováno v:
Journal of the American College of Cardiology. 20(6):1305-1312
Objectives. The goal of this study was to lend insight into the mechanisms responsible for the beneficial effects of combination thrombolytic therapy. Background. Combination thrombolytic therapy for acute myocardial infarction bas been associated wi
Autor:
Desire Collen, Jacqueline M. Doherty, J C Hoak, Marie A. Shatos, David C. Stump, Thomas Orfeo
Publikováno v:
Journal of Biological Chemistry. 267:597-601
Clinical and experimental data indicate that activated oxygen species interfere with vascular endothelial cell function. Here, the impact of extracellular oxidant injury on the fibrinolytic response of cultured human umbilical vein endothelial (HUVE)