Zobrazeno 1 - 9
of 9
pro vyhledávání: '"David C. S. Wong"'
Autor:
Alessandra Stangherlin, Joseph L. Watson, David C. S. Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D. Beale, Edward A. Hayter, Alina Guna, Alison J. Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M. Voorhees, David A. Bechtold, Emmanuel Derivery, Rachel S. Edgar, Peter Newham, John S. O’Neill
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Osmotic compensation by electroneutral ion transport buffers TORC1-mediated changes in the cytosolic proteome, and maintains intracellular homeostasis and cell volume over the circadian cycle. Here, the authors find such ion content changes drive dai
Externí odkaz:
https://doaj.org/article/d608bbcc713a4841b6211ae27b0bfe88
Autor:
Alessandra Stangherlin, Joseph L. Watson, David C. S. Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D. Beale, Edward A. Hayter, Alina Guna, Alison J. Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M. Voorhees, David A. Bechtold, Emmanuel Derivery, Rachel S. Edgar, Peter Newham, John S. O’Neill
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/ce8210b5c1134255b82aa740bd07ccb6
Autor:
David C. S. Wong, Joshua P. Harvey, Neringa Jurkute, Sara M. Thomasy, Mariya Moosajee, Patrick Yu-Wai-Man, Michael J. Gilhooley
Publikováno v:
Journal of Neuro-Ophthalmology.
Autor:
John S. O’Neill, Christine T. Styles, Nina M Rzechorzek, Marrit Putker, Andrew D. Beale, Alessandra Stangherlin, Martin Reed, Aiwei Zeng, Jason Day, Sew Y. Peak-Chew, David C S Wong, Rachel S. Edgar, Estere Seinkmane
Publikováno v:
The EMBO Journal
Wong, D C S, Seinkmane, E, Zeng, A, Stangherlin, A, Rzechorzek, N, Beale, A D, Day, J, Reed, M, Peak-Chew, S Y, Styles, C T, Edgar, R S, Putker, M & O'Neill, J S 2021, ' CRYPTOCHROMES promote daily protein homeostasis ', EMBO Journal, vol. 41, no. 1, e108883 . https://doi.org/10.15252/embj.2021108883
Wong, D C S, Seinkmane, E, Zeng, A, Stangherlin, A, Rzechorzek, N, Beale, A D, Day, J, Reed, M, Peak-Chew, S Y, Styles, C T, Edgar, R S, Putker, M & O'Neill, J S 2021, ' CRYPTOCHROMES promote daily protein homeostasis ', EMBO Journal, vol. 41, no. 1, e108883 . https://doi.org/10.15252/embj.2021108883
The daily organisation of most mammalian cellular functions is attributed to circadian regulation of clock‐controlled protein expression, driven by daily cycles of CRYPTOCHROME‐dependent transcriptional feedback repression. To test this, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a757d2bf8d8f4257af1898e1cc167bc
https://www.repository.cam.ac.uk/handle/1810/331459
https://www.repository.cam.ac.uk/handle/1810/331459
Autor:
Rachel S. Edgar, Andrew D. Beale, Estere Seinkmane, Edward A. Hayter, Alison J. Inglis, Joseph L. Watson, Emmanuel Derivery, Thomas Pons, Sew Peak Chew, Stefan Matile, Aiwei Zeng, Jason Day, Alessandra Stangherlin, Nicolas Lequeux, Rebecca M. Voorhees, Gerben van Ooijen, Silvia Barbiero, John S. O’Neill, Peter Newham, David C S Wong, Marrit Putker, Eline Bartolami, Alina Guna, David A. Bechtold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Nature Communications
Nature Communications
Between 6-20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the daily variation in osmotic potential exerted by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0acfb0784324a2a1b275d73b8240e3
http://hdl.handle.net/10044/1/104009
http://hdl.handle.net/10044/1/104009
Autor:
Aziz Sancar, Michael Vanden Oever, Christopher P. Selby, John S. O’Neill, Rachel S. Edgar, Nathaniel P. Hoyle, Johanna E. Chesham, Estere Seinkmane, Nicolai Peschel, Aiwei Zeng, Kevin A. Feeney, David C S Wong, Robin Fischer, Mathew D. Edwards, Nina M Rzechorzek, Marrit Putker, Ko-Fan Chen
Publikováno v:
The EMBO Journal
Circadian rhythms are a pervasive property of mammalian cells, tissues and behaviour, ensuring physiological adaptation to solar time. Models of cellular timekeeping revolve around transcriptional feedback repression, whereby CLOCK and BMAL1 activate
Autor:
Emmanuel Derivery, Alison J. Inglis, Thomas Pons, Rachel S. Edgar, Joseph L. Watson, Sew Peak Chew, Estere Seinkmane, Aiwei Zeng, Jason Day, Alessandra Stangherlin, Silvia Barbiero, Nicolas Lequeux, Andrew D. Beale, Peter Newham, Stefan Matile, Gerben van Ooijen, Edward A. Hayter, John S. O’Neill, David C S Wong, Eline Bartolami, Alina Guna, David A. Bechtold, Rebecca M. Voorhees
Between 6-20% of the cellular proteome is under circadian control to tune cell function with cycles of environmental change. For cell viability, and to maintain volume within narrow limits, the osmotic pressure exerted by changes in the soluble prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef0a982c18a5abba57f5c0969abaf2fd
https://doi.org/10.1101/2020.05.28.118398
https://doi.org/10.1101/2020.05.28.118398
Autor:
Ko-Fan Chen, John S. O’Neill, Aziz Sancar, Nicolai Peschel, Nina M Rzechorzek, Marrit Putker, Robin Fischer, Nathaniel P. Hoyle, Aiwei Zeng, Johanna E. Chesham, Kevin A. Feeney, Estere Seinkmane, Mathew D. Edwards, Christopher P. Selby, David C S Wong
SummaryCircadian (approximately daily) rhythms are a pervasive property of mammalian cells, tissues, and behaviour, ensuring physiological and metabolic adaptation to solar time. Models of daily cellular timekeeping revolve around transcriptional fee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4a1d387385db7ef4c478c43da6f464
https://doi.org/10.1101/2020.05.14.095968
https://doi.org/10.1101/2020.05.14.095968
Autor:
John S. O’Neill, David C S Wong
Publikováno v:
Current Opinion in Physiology
Highlights • Transcriptional feedback is insufficient to account for circadian rhythm generation. • Post-translational regulators of daily cellular clocks are conserved among eukaryotes. • Eukaryotic circadian timekeeping may result from diverg